Understanding the risk for relapse is important because there
are large differences between the treatments for low-risk, intermediate-risk and high-risk disease. In general, high-risk neuroblastomas are more likely to come back and therefore require stronger treatment than low- or intermediate-risk disease. Stronger treatment selected for high-risk disease has been shown to benefit patients; however, it also has more side effects. Therefore, risk assessment is an essential step in determining appropriate treatment. International teams of neuroblastoma specialists have developed current treatment plans over several decades to carefully balance the benefits and risks of treatment and the chance that treatment will not be successful. Once your doctor has completed all the necessary tests and has assigned a risk category for your child, focus your attention on that particular risk groups treatment section.