FN Thomson Reuters Web of Science

VR 1.0
PT J
AU Zhang, CS
Xie, L
Fan, ZJ
Wang, H
Chen, XP
Li, J
Sun, GA
AF Zhang, Changsheng
Xie, Lei
Fan, Zhijian
Wang, Hong
Chen, Xiping
Li, Jian
Sun, Guangai
TI Straightforward understanding of the structures of metastable alpha ''
and possible ordered phases in uranium-niobium alloys from
crystallographic simulation
SO JOURNAL OF ALLOYS AND COMPOUNDS
AB Crystallographic simulation is carried out in the present work to understand the
respective structure of metastable alpha '' and possible ordered phases, which
could be the prerequisite for revealing the low-temperature aging mechanism
underlying the alpha '' phase in U-Nb alloys. The space group of No. 11 with C-type
lattice is found to describe the structure of alpha '' phase in a straightforward
way, avoiding the mistaken or indirect indexation and analysis of structural data.
The obtained theoretical diffraction pattern of alpha '' phase shows clearly the
phenomenon of peak splitting, in which the Bragg positions also agree well with the
experimental observation. Additional peaks are observed at the low diffraction
angles for the possible ordered phases in U-Nb alloys through simulation on the
proposed two types of structures, which need to be carefully detected by the
uniting of multiprobe diffraction. The correlation between ordered structures and
stress-strain response is also deduced and discussed. The present work would
provide some enlighten to the integrity of the phase diagram and the understanding
of low-temperature aging mechanism in UeNb alloys. (C) 2015 Elsevier B.V. All
rights reserved.
SN 0925-8388
EI 1873-4669
PD NOV 5
PY 2015
VL 648
BP 389
EP 396
DI 10.1016/j.jallcom.2015.06.271
UT WOS:000361158300060
ER

PT J
AU Luo, Q
Lin, TY
Zhang, CY
Zhu, TT
Wang, L
Ji, ZJ
Jia, BY
Ge, T
Peng, DY
Chen, WD
AF Luo, Qing
Lin, Tongyuan
Zhang, Cai Yuan
Zhu, Tingting
Wang, Lei
Ji, Zhaojie
Jia, Buyun
Ge, Tao
Peng, Daiyin
Chen, Weidong
TI A novel glyceryl monoolein-bearing cubosomes for gambogenic acid:
Preparation, cytotoxicity and intracellular uptake
SO INTERNATIONAL JOURNAL OF PHARMACEUTICS
AB Lyotropic cubic liquid crystalline nanoparticles, also known as 'cubosomes',
have been tested as effective carriers for a variety of drugs due to their ability
to enhance delivery efficiency and reduced drug side effects. Cubosomes are
colloidal carriers composed of biodegradable Glyceryl monooleate and F127. Being
composed of well tolerable and physiological materials, these carriers are well
tolerated, compatible and non-toxic. In this study, therefore, we developed a
novel, water-soluble, glyceryl monooleate and F127 based multiblock copolymer for
Gambogenic acid (GNA) by emulsion-evaporation and low temperature-solidification
technique. Physicochemical properties, in vitro cytotoxicity, cellular uptake and
in vivo pharmacokinetic of GNA-loaded cubosomes (GNA-Cubs) were investigated. The
results revealed that GNA-Cubs were spherical or ellipsoidal monocellular by
dynamic light scattering, meanwhile, 150-250 nm in mean size with narrow
polydispersity indexas determined by transmission electron microscopy. Small angle
X-ray scattering indicated that GNA-Cubs retain the Pn3m cubic symmetry. Compared
with GNA solution, GNA-Cubs exhibited markedly prolonged inhibitory activity in
SMMC-7721 cells, as well as time-dependent increases in intra-cellular uptake.
Furthermore, in vivo pharmacokinetic study showed that the C-max values and the AUC
of GNA-Cubs were higher than GNA solution approximately 1.2-fold and 9.1-fold,
respectively. In conclusion, the results showed that the cubic liquid crystalline
nanoparticles could be a potentially nanocarrier in the delivery of GNA for cancer
therapy. (C) 2015 Elsevier B.V. All rights reserved.
SN 0378-5173
EI 1873-3476
PD SEP 30
PY 2015
VL 493
IS 1-2
BP 30
EP 39
DI 10.1016/j.ijpharm.2015.07.036
UT WOS:000360492000004
PM 26209071
ER

PT J
AU Schongart, J
Gribel, R
da Fonseca, SF
Haugaasen, T
AF Schoengart, Jochen
Gribel, Rogerio
da Fonseca-Junior, Sinomar Ferreira
Haugaasen, Torbjorn
TI Age and Growth Patterns of Brazil Nut Trees (Bertholletia excelsa
Bonpl.) in Amazonia, Brazil
SO BIOTROPICA
AB Various techniques have been used to estimate the age of Brazil nut trees
(Bertholletia excelsa Bonpl.), but these techniques produce large discrepancies.
Here, we first verified that two individuals of known ages from a plantation in
central Amazonia, Brazil, have a congruent number of growth rings. The indexed
average tree-ring curve was significantly correlated with total precipitation
during the rainy season (November-June) over a 50-yr period, confirming the annual
nature of the tree rings. Second, we analyzed Brazil nut trees from two populations
in the Trombetas (eastern Amazon) and Purus (central Amazon) regions, performing
tree-ring analysis to estimate tree age and diameter increment rates. We compared
age-diameter relationships, mean passage time through 10-cm diameter size classes,
and growth trajectories of individual trees. The maximum age of Brazil nut trees
analyzed was 361yr in the Purus and 401yr in the Trombetas. Trees at the Purus site
had higher mean diameter increment rates and showed more variation compared to
trees at the Trombetas site. Individual growth trajectories show that the majority
of trees attained the canopy by direct growth, while a smaller number passed
through one release or one suppression event before becoming established in the
canopy. None of the trees passed through multiple release and suppression events.
The age estimations presented here are comparable to previous tree-ring analyses
for the species, and the observed growth patterns support earlier work indicating
B.excelsa as a gap-dependent tree species.
Resumo Varias tecnicas vem sido utilizadas para se estimar a idade de
Castanheiras-do-Para (Bertholletia excelsa Bonpl.). Entretanto, diferentes metodos
apresentaram grande discrepancias em relacAo as estimativas das idades. No presente
estudo, primeiramente verificamos um numero congruente de aneis de crescimento de
dois individuos com idades conhecidas pertencentes a uma plantacAo na Amazonia
Central, Brasil. A curva media indexada dos aneis de crescimento apresentou uma
relacAo significativa com a precipitacAo total durante a estacAo chuvosa (novembro
a junho) ao longo de um periodo de 50 anos, confirmando a natureza anual dos aneis
das arvores. Posteriormente, analisamos os aneis de crescimento a fim de estimar a
idade das arvores da Castanheiras-do-Para e as taxas de incremento de madeira em
duas populacoes: uma na regiAo do rio Trombetas (Amazonia Oriental) e outra no rio
Purus (Amazonia Central). Nestes dois locais, avaliamos as relacoes entre idade e
diametro, o tempo medio para avancarem pelas classes de tamanho de 10cm de diametro
e as trajetorias de crescimento individual das arvores. A idade maxima das
Castanheiras-do-Para analisadas foi de 361 anos no Purus, e de 401 anos no
Trombetas. As taxas de incremento diametrico medio foram altas e mais variaveis no
Purus do que no Trombetas. As trajetorias de crescimento individual mostraram que a
maioria das arvores atingiu o dossel por crescimento direto, enquanto um numero
menor passou por um evento de liberacAo ou supressAo antes de se estabelecer no
dossel. Nenhuma das arvores passou por eventos multiplos de liberacAo ou supressAo.
As estimativas de idade apresentadas aqui sAo comparaveis as analises anteriores de
aneis de crescimento para a especie e os padroes de crescimento observados
corroboram estudos anteriores indicando que a Castanheira-do-Para e uma especie
arborea dependente de clareiras.
SN 0006-3606
EI 1744-7429
PD SEP
PY 2015
VL 47
IS 5
BP 550
EP 558
DI 10.1111/btp.12243
UT WOS:000361470100006
ER

PT J
AU Acocella, N
Di Bartolomeo, G
 Tirelli, P
AF Acocella, Nicola
Di Bartolomeo, Giovanni
Tirelli, Patrizio
TI US TREND INFLATION REINTERPRETED: THE ROLE OF FISCAL POLICIES AND
TIME-VARYING NOMINAL RIGIDITIES
SO MACROECONOMIC DYNAMICS
AB This paper offers a reinterpretation of the Fed's time-varying implicit
inflation target, based on two considerations. The first is that the need to
alleviate the burden of distortionary taxation may justify the choice of a positive
inflation rate. The second is based on compelling evidence that the degree of price
and wage indexation falls with trend inflation. In fact, we find that a proper
characterization of the joint evolution of fiscal variables and nominal rigidities
has a strong impact on the Ramsey optimal policies, implying optimal inflation
dynamics that are consistent with the observed evolution of U.S. trend inflation.
By contrast, tax policies have been too lax, especially at the time of the
controversial Bush tax cuts.
SN 1365-1005
EI 1469-8056
PD SEP
PY 2015
VL 19
IS 6
SI SI
BP 1294
EP 1308
DI 10.1017/S1365100513000837
UT WOS:000361056300007
ER

PT J
AU Mettela, G
Kulkarni, GU
AF Mettela, Gangaiah
Kulkarni, Giridhar U.
TI Facet selective etching of Au microcrystallites
SO NANO RESEARCH
AB High-symmetry crystals exhibit isotropic properties. Inducing anisotropy, e.g.,
by facet selective etching, is considered implausible in face-centered cubic (FCC)
metals, particularly gold, which, in addition to being an FCC, is noble. We report
for the first time the facet selective etching of Au microcrystals obtained in the
form of cuboctahedra and pentagonal rods from the thermolysis of a goldorganic
precursor. The selective etching of {111} and {100} facets was achieved using a
capping method in which tetraoctylammonium cations selectively cap the {111} facets
while Br- ions protect the {100} facets. The exposed facets are oxidized by O-
2/Cl-, yielding a variety of interesting geometries. The facet selective etching of
the Au microcrystallites is governed only by the nature of the facets; the geometry
of the microcystallite does not appear to play a significant role. The etched
surfaces appear rough, but a closer examination reveals well-defined corrugations
that are indexable to high hkl values. Such surfaces exhibit enhanced Raman
activity.
SN 1998-0124
EI 1998-0000
PD SEP
PY 2015
VL 8
IS 9
BP 2925
EP 2934
DI 10.1007/s12274-015-0797-8
UT WOS:000361057000014
ER

PT J
AU Ascari, G
Branzoli, N
AF Ascari, Guido
Branzoli, Nicola
TI INFLATION PERSISTENCE, PRICE INDEXATION AND OPTIMAL SIMPLE INTEREST RATE
RULES
SO MANCHESTER SCHOOL
AB We study the properties of the optimal interest rate rule under different
sources of inflation persistence. In our model, the optimal policy minimizes price
dispersion, which depends on the degree of price indexation. When indexation is
zero, inflation persistence depends only on the level of trend inflation, the
inflation gap is purely forward-looking and the optimal policy targets inflation
stability. Full indexation makes the inflation gap persistent, eliminates the
effects of trend inflation and makes the optimal policy target the real interest
rate. We compare our results with empirical estimates of the FED's policy in the
post-WWII era.
SN 1463-6786
EI 1467-9957
PD SEP
PY 2015
VL 83
SU 3
SI SI
BP 1
EP 30
DI 10.1111/manc.12117
UT WOS:000360310900001
ER

PT J
AU Sene, A
Kamsu-Foguem, B
Rumeau, P
AF Sene, A.
Kamsu-Foguem, B.
Rumeau, P.
TI Telemedicine framework using case-based reasoning with evidences
SO COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
AB Telemedicine is the medical practice of information exchanged from one location
to another through electronic communications to improve the delivery of health care
services. This research article describes a telemedicine framework with knowledge
engineering using taxonomic reasoning of ontology modeling and semantic similarity.
In addition to being a precious support in the procedure of medical decision-
making, this framework can be used to strengthen significant collaborations and
traceability that are important for the development of official deployment of
telemedicine applications. Adequate mechanisms for information management with
traceability of the reasoning process are also essential in the fields of
epidemiology and public health. In this paper we enrich the case-based reasoning
process by taking into account former evidence-based knowledge. We use the regular
four steps approach and implement an additional (iii) step: (i) establish
diagnosis, (ii) retrieve treatment, (iii) apply evidence, (iv) adaptation, (v)
retain. Each step is performed using tools from knowledge engineering and
information processing (natural language processing, ontology, indexation,
algorithm, etc.). The case representation is done by the taxonomy component of a
medical ontology model. The proposed approach is illustrated with an example from
the oncology domain. Medical ontology allows a good and efficient modeling of the
patient and his treatment. We are pointing up the role of evidences and
specialist's opinions in effectiveness and safety of care. (C) 2015 Elsevier
Ireland Ltd. All rights reserved.
SN 0169-2607
EI 1872-7565
PD AUG
PY 2015
VL 121
IS 1
BP 21
EP 35
DI 10.1016/j.cmpb.2015.04.012
UT WOS:000356644200003
PM 26001421
ER

PT J
AU Agbo, M
AF Agbo, Maxime
TI A perpetual search for talents across overlapping generations: A
learning process
SO MATHEMATICAL SOCIAL SCIENCES
AB We consider a class of multi-armed bandit problems which is at the same time an
arm-acquiring, restless and mortal bandit, and where the rewards follow any
distribution. This is the case for a committee whose mission is to select the best
element of a set of talents who live for K periods, and who have different
seniorities. In each period, new young talents enter the set. We find that if K is
infinite the problem is indexable. However, the index we find is different from
that of Gittins, and is easier to be implemented. If K is finite the problem is not
indexable. In that case, we solve partially the problem. Under some condition, we
develop a criterion to compare two talents. We also find that the solution we
propose is still optimal in case of multiple plays. (C) 2015 Elsevier B.V. All
rights reserved.
SN 0165-4896
EI 1879-3118
PD JUL
PY 2015
VL 76
BP 131
EP 145
DI 10.1016/j.mathsocsci.2015.05.002
UT WOS:000358268500015
ER

PT J
AU Bruni, R
Cesarone, F
Scozzari, A
Tardella, F
AF Bruni, Renato
Cesarone, Francesco
Scozzari, Andrea
Tardella, Fabio
TI A linear risk-return model for enhanced indexation in portfolio
optimization
SO OR SPECTRUM
AB Enhanced indexation (EI) is the problem of selecting a portfolio that should
produce excess return with respect to a given benchmark index. In this work, we
propose a linear bi-objective optimization approach to EI that maximizes average
excess return and minimizes underperformance over a learning period. Our model can
be efficiently solved to optimality by means of standard linear programming
techniques. On the theoretical side, we investigate conditions that guarantee or
forbid the existence of a portfolio strictly outperforming the index. On the
practical side, we support our model with extensive empirical analysis on publicly
available real-world financial datasets, including comparison with previous
studies, performance and diversification analysis, and verification of some of the
proposed theoretical results on real data.
OI SCOZZARI, Andrea/0000-0003-3038-3957
SN 0171-6468
EI 1436-6304
PD JUL
PY 2015
VL 37
IS 3
SI SI
BP 735
EP 759
DI 10.1007/s00291-014-0383-6
UT WOS:000356732400008
ER

PT J
AU Chen, D
Dempsey, M
Lajbcygier, P
AF Chen, Doris
Dempsey, Michael
Lajbcygier, Paul
TI Is Fundamental Indexation able to time the market? Evidence from the Dow
Jones Industrial Average and the Russell 1000
SO JOURNAL OF INTERNATIONAL FINANCIAL MARKETS INSTITUTIONS & MONEY
AB Fundamental Indexation weights stock according to a firm's economic size, not
stock price or market capitalization. This means that at least in theory, unlike
traditional market capitalization weighted indexes, it prevents overinvestment in
overpriced stock and vice versa. It should therefore effectively time the market by
avoiding incorrect investment in cyclically mispriced stock. We ascertain if
Fundamental Indexation outperforms traditional indexing and whether any
outperformance can be attributed to market timing. Using almost fifty years of Dow
Jones Industrial Average index and Russell 1000 index returns, we find some
evidence of limited market timing but no evidence of overall positive abnormal
performance. Crown Copyright (C) 2015 Published by Elsevier B.V. All rights
reserved.
SN 1042-4431
PD JUL
PY 2015
VL 37
BP 162
EP 177
DI 10.1016/j.intfin.2015.02.001
UT WOS:000356599300011
ER

EF