LEVETIRACETAM

M 500 mg/INJ

Anticonvulsant
CrCl>80 500-1,500 mg
mL/min/1.73 m2 q 12 hrs
CrCl 50-80 500-1,000 mg
100 ml NSS, LR mL/min/1.73 m2 q 12 hrs
D5W CrCl 30-50 250-750 mg q
mL/min/1.73 m2 12 hrs
CrCl<30 250-500 mg q
100 ml mL/min/1.73 m2 12 hrs
ESRD requiring Dialyzable
hemodialysis (50%);
500-1,000 mg

24 q 24 hrs
hrs supplemental
dose 250-500
mg post-HD
Peritoneal dialysis 500-1,000 mg
IV infusion 15 (PD) q 24 hrs
IV push CRRT 250-750 mg q
12 hrs

:



Agent
A Agent B
Effect
Levetiracetam Alcohol Level of
,
Alcohol
SSRIs Level of SSRIs

Drug Interaction
Hydroxyzine, Level of
MgSO4 Levetiracetam