ASSIGNMENT #3

NAME: GALES, MA. ROCHELLE MAJHAL C.

Section: PH 3B

LINCOMYCINS

MODE OF
NAME OF DRUG SPECTRUM OF ACTIVITY SIDE EFFECTS
ADMINISTRATION
Pseudomembranous
colitis
Streptococci
Nausea and vomiting
Staphylococci
CLINDAMYCIN Oral Diarrhea
Pneumococci
HCL Heartburn
Non-spore-forming anaerobic
Joint pain/swelling
bacteria (Bacteroides spp.)
Yellowing eyes/skin,
dark urine
Active against
Nausea and vomiting
Bacteroidesfragilis,
CLINDAMYCIN Upset stomach
Oral P. jiroveci,
PALMITATE Mild diarrhea
T. gondii,
HCL
T. clostridium,
Corynebacterium
Effective for infections due to
anaerobes
(particularly Bacteroidesspp,
including B. fragilis),
community-acquired
methicillin-
resistant Staphylococcus Burning
aureus, and macrolide- Itching
CLINDAMYCIN
resistant, clindamycin- Dryness
PHOSPHATE Topical
susceptible Streptococcus Redness
(GEL)
pneumoniae Oily skin
Not reliably active against Skin peeling
mycoplasmas,
chlamydiae, Chlamydophila
o spp, and legionellae
Aerobic gram-negative bacilli
and enterococci are resistant.
 ASSIGNMENT #3
NAME: GALES, MA. ROCHELLE MAJHAL C.
Section: PH 3B

POLYPEPTIDES

MODE OF
NAME OF
ADMINISTRATIO SPECTRUM OF ACTIVITY SIDE EFFECTS
DRUG
N
Not active against
Skin rash
Itching
Proteus, Providencia, Burkhold
Red, swollen,
eria, and Serratia spp and some
BACITRACIN Topical blistered or peeling
obligate anaerobes,
skin
including Bacteroides
Wheezing
fragilis and gram-positive
bacteria.
Have rapid concentration-
dependent bactericidal activity
against: Temporary eye
Most facultative and aerobic stinging/blurring/r
POLYMYXIN B Ophthalmic gram-negative bacilli, edness/itchiness
including Pseudomonas Temporary blurred
aeruginosa and Acinetobacter vision
o spp

Active against:
Most gram-positive cocci and
bacilli, including almost
all Staphylococcus aureus and
coagulase-negative
staphylococcal strains that are
Stomach upset
VANCOMYCIN resistant to penicillins and
Oral Itching
HCL cephalosporins
Many strains of enterococci (via
a bacteriostatic mechanism)
However, many strains of
enterococci and some strains
of S. aureus are resistant.
 ASSIGNMENT #3
NAME: GALES, MA. ROCHELLE MAJHAL C.
Section: PH 3B

UNCLASSIFIED ANITBIOTICS

MODE OF
NAME OF DRUG ADMINISTRAT SPECTRUM OF ACTIVITY SIDE EFFECTS
ION
Wide spectrum of
activity against: Diarrhea
Gram-positive and gram- Nausea and vomiting
negative cocci and bacilli Bone marrow
CHLORAMPHENICOL Oral (including anaerobes) depression
Rickettsia, Mycoplasma, Chl Gray baby syndrome (in
amydia, neonates)
and Chlamydophila spp

Gram (+) and gram (-)

cocci, including
staphylococci, streptococci,
Neisseria spp., and M.
Burning
Catarrhalis
Stinging
Not effective against
MUPIROCIN Topical Pain
enterococci or anaerobic
Itching
bacteria
Rash
Poor activity against most
gram (-) and gram (+) bacilli
except H. Influenza