GN4II NAME. EXAM 1 Fall 2000 Seat Number Student ID__ DIRECTIONS: Read each question carefully at the beginning of the exam period, Ask for help if the question is unclear. The number in parentheses by each question is the points for that question, Enough space is given by each question for a complete answer. Partial credit is given for partial answers. Please fill in your name and student ID on each page now!! ‘You may need the following section of the Chi-square table for p=0.08. dere eee sea| seed esea ere Ga aeOeal iO iadt Chi-Square | 3.84 | 5.99 | 7.82 | 9.49 [11.07 [12.59 [14.07 | 15.51 | 16.92 | 18.31 | 19.68 1. (20) Short Answer. Answer each of the following questions in the space provided. You will be counted off for explanations that are not succinct. a) Give the chromosomal nomenclature for Turner Syndrome an: Geserity two symptoms. 4S, X lar 1X0) oa Slot ches vapobl Bred Shon cba lag et Te Welles af Mack SeHicf Frblrns b) Describe what is meant by the phrase, "He is hemizygous for hemophilia." For wales, Hig co om be hemisggms, os tug onl ba oe cry Ha pe 47, ©) What is ae Li ts i we 7 xX pect vate ae , BAe i ete te (a0 2 d) What is meant by the phrase “equgtional —) Divisio, vl 4 Num & a f ch towns erates re mawty sed 7 7 as is Ht weno! diyiss divs iay we Mtodiis [24Genetics 411, Exam 1, Fall 2000 2. (15) Page 2 of 5. NAME ‘Finite Taney ‘The following is a pedigree for a Simple Recessive Trait, Assume individuals entering the pedigree do not carry the allele for this trait unless there is evidence to the contrary. 1 A on Ox 4 aa on fa I 2Y, Fas 1 2 3 FE} Tl Aa 4A4 the 1 fe ane ZA te IV bl i del | waa a) Write the genotypes for all individuals in Generations I - III. Give probabilities for the genotypes when you can, and a dash (~) when you cannot. b) The probability the indicated individual in Generation IV will have the characteristic is $ : 3. © __Foreach of the following human pedigrees, CIRCLE those modes of inheritance which ean be excluded. ae Autosomal Autosomal Recessive Recessive X-Linked X-Linked Recessive Recessive X-Linked X-Linked Dominant Dominant None can be None can be excluded excluded LidGeneties 411, Exam 1, Fall 2000 Page 3 of5 NAME FatRaney aay 4, (10) Researchers are interested in several attributes of wild daisies, We have done a large experiment to determine the linkage of three of these traits, Petal Size, Plant Size, and Petal Color. ‘The results from a typical testcross of the Fy are: Petal Size Plant Size Petal Color Number Observed Long Tall White 2 Short Tall White 1,435 Short Dwarf Pink 4 Long, Dwarf Pink 1,372 Long Dwarf White 139 Short Tall Pink 178 Long Tall Pink 156 Short Dwarf White 184 Total 3,470 ‘We have determined the order on the chromosome to be: Plant Size, Petal Size, Petal Color, a) Write the F; with the loci in the correct order Duet Long Ki kh she? Who ») 9.30 SoM Compute the A ect ou Size and Ges Oh bony wlsty 15 (394/791 L+9 BET WS aa ise + D6e.(%4) 3470 TM Shp ©) 0.5764 _ Regardtess of your answer to b), assume the map distance between Petal Size and Peial Color is 6 and between Petal Color and Plant Size is 5. Compute the Coefficient of Coincidence. Obs, 0CO bid | Exp 000 * (oekoii = OST64 5. (8) Circle the phenotypic sex of individuals with the given chromosomal arrangements. Organism | Sex Chromosomes Ploid; Sex (Circle ONE) Drosophila XXXYY Triploid Male Gemals) Intersex Drosophila x |__ Diploid fale) Female Intersex Human XXYY Diploid (ald Female Intersex Human XYY Diploid (Male) Female IntersexGenetics 411, Exam 1, Fall 2000 Page 4of5 NAME army aay 6. (4) — Give the name of the type of epistatic interaction for each of the following traits, based on the phenotypic ratios from a dihybrid cross, ("Type of Epistasis Ratio from Dihybrid ce Duplicate Dow vot Baitesis re Singh Keceasie Goritas/s on 7. (10) We are interested in determining whether Scale Color for a variety of snake shows Partial Dominance. The following are the data collected from a Monohybrid cross. [Phenotype Observations —_| Expected Chi-Square_ 150.5 1.5963 Red 135, 150.5 0.015 Green 152 aaesdeiassiecetiaiet HHHEeeee ee 301 0.6512 Orange 315 | 602 2.2625 [ Total 602_ 2) Complete the Table, (one) b) State the hypothesis for this experiment. Seale color ty i lerihll AA Pachel Dorm nF Maig note ©) What are the degrees of freedom for this experiment? 4d) The statistical conclusion is (circle one) Reject the Hypothesis (Kail to Reject the Hypothesis ¢) State your conclusion of this test in terms of the genetics involved for this experiment, Be carefil how you word your conclusion. Tho bth. Lyre cons hit ith sccle, Cole shading patil Gent rhe Aan CO,Genetics 411, Exam 1, Fall 2000 Page 5of5 NAME oo) Tay 8, (18) _In order to improve the Technician and to save money, monkeys are being bred to retype articles, from reporters. After several semesters, some Undergraduate Genetics Minors have identified three traits of interest and mapped them as given below ‘Typing Skill Editing Ability Personality Good Average ‘Aggressive Dominant Poor Excellent Nonaperessve Recessive 9 5 C=06 A true breeding strain of monkeys who have Good typing skills, Excellent editing ability and are Aggressive is crossed with a true breeding strain who have Poor typing skills, Average editing ability and are Nonaggressive, The F; is testerossed. Answer each question concerning the expected frequency of the testeross offspring, (Give at least 5 decimal places accuragy). os : ner Ayre : OLE Give the frequetey of Monkeys with Excellent euighe ability whe mokionensssdeeve, £ ¢ Os i) 5 GOL O.OFS Give the frequency of Monkeys with Excellent editing ability and Poor typing skill. t EC 09 j= OPI B.001 3.5 Give the frequency of aes ei ad ie & Averages editing, who are Aggressive. DLE = CPS \a)= 00d Lap hel) G00 3- 2.2673 Give the frequency of Monkeys with Good typing who are Nonaggressive. oo! Eralhct Kenagzressit EC 08 — 0007) Goo! Auer. Um ©9908 He ECOG = 20d) 0.06130 i 9. (9) Hemophilia is an X-linked recessive trait. A woman who is a carrier for hemophilia mates with a man who comes from a family with no history of hemophilia. Uh, x H Y a) ___C?___ whatis the chance that a female offspring will have hemophilia? _1 y a Sh fina fede ») L ‘What is the chance that a male offspring will have hemophilia? ° One of the female offspring mates with a male from a family with no history of emophiia, What i the chance a male offspring wll have hemophilia? (Wye LH) He %yy ¥ MX a