14/04/2016

Patobiologi Keganasan saraf

Abu bakar

Adaptasi sel

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14/04/2016

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 14/04/2016

Brain Facts
Primary brain tumors compose a heterogeneous group of neoplasms that
vary widely by site of origin, morphologic features, growth potential, extent
of potential invasiveness and tendency for progression, and recurrence and
treatment response.
Types:
Benign brain tumor- slow-growing cells, distinct borders, rarely spreads, may be life threatening
because of its location in the brain, often needs only a craniotomy resection
Malignant brain tumor- fast-growing cells, invasive of surrounding tissues, often spreads to other
places in the CNS, very life-threatening, requires many therapy treatments like a craniotomy,
radiation & chemotherapy
Anatomical Locations:
Brain, cranial nerves spinal cord, meninges, ventricle, cerebellum, pituitary, pineal, nasal cavity,
other CNS,
Classifications:
Tumors of neuroepithelial tissue (i.e., astrocytic tumors, oligodendroglial
tumors, ependymal tumors, glioblastoma multiforme tumor)
Tumors of the meninges (i.e., meningioma)
Tumors of cranial and spinal nerves (i.e., schwannoma, neurofibroma)
Hematopoietic neoplasms (i.e., malignant lymphoma)
Germ cell tumors (i.e., teratoma)
Cysts and tumors such as lesions (i.e., Rathke cleft cyst, epidermoid cyst)
Tumors of the sellar region (i.e., pituitary adenoma)
Local extensions from regional tumors (i.e., paraganglioma, chordoma)
Metastatic tumors