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Autosomal Recessive Inheritance

Important features that distinguish autosomal recessive inheritance:


Because autosomal recessive alleles are clinically expressed only in the
homozygous state, the offspring must inherit one copy of the diseasecausing
allele from each parent.
In contrast to autosomal dominant diseases, autosomal recessive
diseases are typically seen in only one generation of a pedigree (see
Figure II-1-4).
Because these genes are located on autosomes,

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