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Part 3 derma Dr. Tarek ...... .......

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Syphilis
specific test non specific test
syphilis

Non specific diagnosis


positive specific tests

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Part 3 derma Dr. Tarek ...... .......

follow up treatment

tests non specific diagnostic test


follow up test

: specific tests
treponema pallidum immobilization test
serum trepenoma pallidum
specific anti bodies
,,
,, Immobilization arrest Movement
,,
treponema pallidum
syphilis

specific anti body syphilis Organism


,,
treponema

test ,, fluorescence treponema pallidum anti body titer


tests
fluorescent treponemal antibody absortbed test

treponema hem agglutination test

specific test

,, specific Non specific
specific more specific

non specific : Wasserman venereal disease research lab


follow up
positive
specific test

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Part 3 derma Dr. Tarek ...... .......

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stages of syphilis
acquired congenital

acquired syphilis ,, early Late


: early
Primary chancre
secondary
early latent

: Late
late latent
tertiary
Cardio vascular C.N.S.

congenital transplacental
Early
Late
Stigmata

,, Primary ,, secondary tertiary


latent
Primary syphilis secondary syphilis
latent

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Latent


,, early latent first two years secondary stage
,, late latent secondary stage

tertiary
,, characterized by gumma

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Part 3 derma Dr. Tarek ...... .......

C.N.S cardio vascular


tertiary syphilis

tertiary syphilis
C.N.S. cardiovascular
gumma
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C.N.S. cardiovascular
gumma skin cardio vascular gumma

C.N.S.
skin ,, gumma C.N.S. gumma

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Modification tertiary

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,, clinical pictures
primary syphilis
chancre
syphilis ,, stage

Primary syphilis chancre


chancre
papule ,, well demarcated ,, Rounded patch
edge ,, raised
painless

chancre well demarcated ,, rounded


,, Elevated raised border sloping center
painless


Genital

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Part 3 derma Dr. Tarek ...... .......

extra genital

Genital ,, Male ,, glans of the penis shaft penis


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female
Labia minora ,, labia major ,, forchette

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extra genital
fingers ,, Hand ,, tonsils ,, lips Nipples
classical chancre
first stage

abnormal types
,, even chancre adherent
chancre chancroid painful
condom chancre condom ,, Intercourse
concealed ,, concealed chancre ,, ,,
Intra meatal uretheral meatus
,, Intra renal renal canal

andrology : chancre ,, renal


,, canal ,, uretheral meatus abnormal forms

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chancre

specific test

differential diagnosis
,, genital genital chancre genital lesion
,, scabies ,, herps genitalis Lymph granuloma inguinal
,, venerum
chancre

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Part 3 derma Dr. Tarek ...... .......

,, extra genital
,, T.B. ,, psoriasis Leprosy
primary syphilis

chancre
chancre abnormal forms
: chancre
rounded oval raised border ,,
genital area
,, extra genital Nipple fingers

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other forms
,, ,, condom chancre chancre chancroid Painful condition

Primary syphilis
: chancre abnormal forms


secondary syphilis
,, secondary syphilis form
,, skin rash
condyloma lata ,,
Lymph nodes ,,
mucous membrane lesion ,,
Others ,,

,, secondary syphilis : secondary syphilis


skin rash : ,, polymorphic
skin lesion
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Never

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Part 3 derma Dr. Tarek ...... .......




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