Sản Xuất Acid Glutamic 25850L 1 Ngày

n tt nghip 0 GVHD: PGS.TS.
Trng Th Minh Hnh
LUN VN TT NGHIP
TI: Thit k nh my sn xut

axit glutamic
GVHD: PGS.TS. Trng Th Minh Hnh
Thit k nh my sn xut axit glutamic

n tt nghip 1 GVHD: PGS.TS. Trng Th Minh Hnh
MC LC
M U ................................................................................................................ 0
CHNG I LP LUN KINH T K THUT ................................................... 4
1.1.c im t nhin ca tnh Qung Nam ........................................................ 5
1.2. Vng nguyn liu .......................................................................................... 5
1.3. Hp tc ha ................................................................................................... 5
1.4. Ngun cung cp in, hi v nhin liu ........................................................ 5
1.5. Ngun cung cp nc v vn x l nc .................................................. 6
1.6.Giao thng vn ti: ......................................................................................... 6
1.7. Nhn cng v th trng tiu th ................................................................... 6
1.8. Ngun tiu th sn phm ............................................................................... 6
CHNG II TNG QUAN TI LIU .................................................................. 8
2.1.Tinh bt sn ................................................................................................... 8
2.2.M chnh v axit glutamic ............................................................................... 8
2.3. Phng php sn xut axit glutamic: ........................................................... 10
2.4.Chng vi sinh ............................................................................................... 11
2.5.Nhng yu t nh hng n qu trnh ln men .......................................... 13
CHNG III CHN V THUYT MINH DY CHUYN CNG NGH ....... 15
3.1.Chn phng php sn xut ........................................................................ 15
3.2.Quy trnh sn xut axit glutamic t tinh bt sn .......................................... 16
3.3 Thuyt minh quy trnh sn xut .................................................................... 17
CHNG IV CN BNG VT CHT .............................................................. 29
4.1 Chn cc s liu ban u .............................................................................. 29
4.2. Biu sn xut .......................................................................................... 29
4.3 Cn bng vt liu ......................................................................................... 30
4.4. Tng kt ...................................................................................................... 35
CHNG V TNH V CHN THIT B ........................................................... 36
5.1. Xylo cha tinh bt: ..................................................................................... 36
5.2. Thit b ha tan............................................................................................ 37
5.3. Thit b dch ha........................................................................................... 38
5.4. Thit b ng ha ....................................................................................... 39
5.5. Thng pha ch dch ln men:....................................................................... 39
5.6. Thit b thanh trng v lm ngui: ................................................................. 41
5.7.Thit b nhn ging cp I:............................................................................. 41
5.8. Thit b nhn ging cp II: .......................................................................... 42
5.9.Thit b nhn ging cp III ........................................................................... 43
5.10. Thit b ln men ........................................................................................ 43
5.11. Thit b lc ra .......................................................................................... 44
5.12.Thit b c c............................................................................................ 45
5.13. Thit b ty mu: ....................................................................................... 45
5.14. Thit b kt tinh: ........................................................................................ 46

5.15.Thit b ly tm ............................................................................................ 47
5.16. Thit b lc ................................................................................................ 48
5.17. Sy rung tng si ....................................................................................... 48
5.18.Thit b phn loi......................................................................................... 49
5.19. Thit b ng gi ....................................................................................... 50
5.20. Chn gu ti .............................................................................................. 50
5.21. Chn bm ................................................................................................. 51
5.22.Thng cha ................................................................................................ 53
CHNG VI TNH T CHC V XY DNG ............................................... 55
6.1.Tnh t chc: ................................................................................................ 55
6.2. Tnh xy dng nh my: .............................................................................. 59
6.3. Qui cch xy dng nh my: ....................................................................... 65
CHNG VII TNH HI NC ..................................................................... 69
7.1. Tnh hi. ..................................................................................................... 69
7.2. Tnh nc.................................................................................................... 79
CHNG VIII KIM TRA SN XUT V NH GI CHT LNG SN
PHM ................................................................................................................... 80
8.1. Kim tra u vo ca nguyn liu ............................................................... 80
8.2. Kim tra cc cng on sn xut ................................................................. 80
8.3. Kim tra cht lng sn phm ..................................................................... 81
CHNG IX AN TON LAO NG ................................................................ 82
9.1. Cc nguyn nhn gy tai nn lao ng: ...................................................... 82
9.2. Nhng bin php hn ch tai nn lao ng: ................................................. 82
9.3. Nhng yu cu c th v an ton lao ng: ................................................. 83
KT LUN ........................................................................................................... 85
TI LIU THAM KHO ..................................................................................... 86

M U
Nc ta c ngun sn di do nht, chng c trng khp c ba min t
nc. Vi c tnh d trng, sn lng cao, u t t nn tinh bt sn tng i r
so vi cc loi tinh bt khc. V vy tinh bt sn thch hp lm nguyn liu sn
xut ra cc sn phm phc v cho cng nghip thc phm.
Trong cng ngh sn xut v ch bin thc phm, bt ngt (m chnh) l cht
ph gia thc phm c s dng kh rng ri. M chnh l mui mononatri ca axit
glutamic. Hin nay nc ta vn cn t cc nh my sn xut axit glutamic, m
phn ln l nhp t nc ngoi, y l li th xy dng nh my sn xut axit
glutamic cung cp cho th trng trong nc.
Axit glutamic thuc loi axit amin thay th nhng c vai tr quan trng trong
qu trnh trao i cht c th ngi v ng vt.
Axit glutamic tham gia cu to nn cht xm v cht trng ca no, kch
thch cc phn ng oxi ho ca no.
Khi vo c th, axit glutamic chuyn ha di dng glutamat. Mi ngy, c
th cn khong 10 gam glutamat, ring no cn khong 2,3 gam glutamat.
Axit glutamic tham gia vo vic to thnh protein v hng lot cc axit amin
khc nh: alanin, propin, xystin.V vy, trong y hc, axit glutamic c xem l cht
b no, cha cc bnh thn kinh phn lp, bnh chm pht trin v tr no, v tim
mch, cc bnh v c bp tht.
Ngoi ra, axit glutamic l ngun nguyn liu ch yu sn xut bt ngt v
mt s cht iu v khc, mc ch ca n l to hng v, lm thc n thm ngon
hn.
Axit glutamic cn l ngun nguyn liu khi u cho vic tng hp mt s
ho cht quan trng.
Vic sn xut axit glutamic l mt vic cn thit, l ngnh cng nghip quan
trng cho cng nghip ch bin thc phm, dc phm ni ring v ngnh cng
nghip ni chung.

C nhiu phng php sn xut song c 4 phng php c bn: tng hp ho hc,
thu phn protit, ln men v kt hp. Song phng php ln men c nhiu u im
hn: khng s dng nguyn liu protit, khng cn s dng nhiu ho cht v thit b
chu n mn, hiu sut cao, gi thnh h, to ra axit glutamic dng L, c hot tnh
sinh hc cao.
V vy, p ng nhu cu trong nc v tin ti xut khu, nn em c
giao ti thit k nh my sn xut axit glutamic vi nng sut 4570 tn sn
phm/nm.
CHNG I
LP LUN KINH T - K THUT
Khu vc min Trung cha c nh my sn xut axit glutamic trong khi
ngun nguyn liu phc v sn xut ca khu vc cng rt phong ph. y l mt
iu kin rt thun li chng ta tin hnh sn xut loi sn phm ny nhm cung

cp cho th trng rng ln v tin n xut khu. Vi nhng u im nh vy nn

vic xy dng mt nh my sn xut axit glutamic Qung Nam l vic lm hp l
v s mang li hiu qu kinh t cao trong qu trnh hot ng.
1.1.c im t nhin ca tnh Qung Nam [16]
Qung Nam nm trung ca Vit Nam, pha Bc gip Hu v Nng,
pha Nam gip tnh Qung Ngi, pha Ty gip CHDCND Lo v tnh KonTum,
pha ng gip bin ng.
Kh hu nhit i gi ma; m khng kh trung bnh 84%; gi ng Bc
t thng 10 n thng 3 nm sau ( vn tc gi trung bnh 6-10m/s); gi Nam, ng
Nam, Ty Nam t thng 5 n thng 8 (vn tc gi trung bnh-6 m/s). Nhit
trung bnh:25,4oC. Ma ng dao ng t 29-24oC. Lng ma trung bnh hng
nm: 2580mm, tp trung trong cc thng 9,10,11( chim 85% lng ma c nm).
1.2. Vng nguyn liu
Qung Nam c nh my tinh bt sn FOCOCEV, ng thi tnh Qung
Nam cn gip vi tnh Qung Ngi, Bnh nh s l ngun cung cp nguyn liu
cho nh my rt thun li.
1.3. Hp tc ha
thun li cho vic thu mua nguyn liu cng nh tiu th sn phm, ph
phm trong qu trnh sn xut, nh my cn hp tc ha vi cc nh my khc trong
v ngoi tnh nh nh my ng, nh my tinh bt sn, nh my thc n gia
sccng nh c s dng nhng cng trnh chung nh: in, nc, giao thng,
nc thi,.. gim bt vn u t xy dng, rt ngn thi gian hon vn, h gi
thnh sn phm.
1.4. Ngun cung cp in, hi v nhin liu [34]
S dng t h thng li in quc gia 500KV truyn ti v KCN bng ng
dy 110KV. Ti chn KCN c Trm bin p 40 MVA (110/22), mng 22 KV trong
KCN.

Lng hi t cung cp cho cc phn xng ly t l hi ring ca nh my.

Nhin liu dng cho l hi l du DO c cung cp t cc trm xng du trong
tnh.
1.5. Ngun cung cp nc v vn x l nc [34]
Trong KCN c Nh my nc cng sut 5.000 m3/ngy m cung cp cho cc
Nh my. H thng thot nc v x l nc thi hon chnh
1.6.Giao thng vn ti:
Nm gn Nng, l u mi giao thng quan trng ca hai min Nam Bc.
Cch cng Tin Sa 29km v pha Bc Ngoi ra cn c tuyn quc l 14B ni
Nng vi Ty Nguyn v Lo, Thi Lan. Do thun li cho vic vn chuyn
nguyn liu v sn phm. Knh vn chuyn a dng vi ng st, ng b,
ng thu, ng hng khng l nhng iu kin thun li v giao thng.
1.7. Nhn cng v th trng tiu th
Ngun nhn cng s c tuyn t ngun lao ng ca a phng v cc
vng ln cn, lng lao ng vn lai cng di do t c th thu nhn cng vi
gi r.
Th trng tiu th c chn l th trng ca c nc v hng n xut
khu sang cc nc trong khu vc, c bit l khu vc ng Nam .
1.8. Ngun tiu th sn phm
Ngun tiu th sn phm ch yu ca cng ty l hng vo cng ty Dc
Bnh nh Bidiphar, cc cng ty ch bin thc n gia sc, gia cm trong khu vc v
y l cc cng ty cn mt lng ln axit glutamic phc v cho sn xut hng
nm. Ngoi ra, cc ph phm trong qu trnh sn xut cng lm nguyn liu cho nh
my phn bn phc v cho trng trt.
Bn cnh xut khu sn phm sang cc nc Lo v Campuchia cng l th
trng cn c hng ti trong qu trnh hot ng ca nh my.
Kt lun: Vi nhng iu kin thun li trn l hon ton c th xy dng
v m bo cho s hot ng ca mt nh my sn xut axit glutamic ti tnh
Qung Nam.


CHNG II
TNG QUAN V TI LIU
2.1.Tinh bt sn [1],[5]
Tinh bt sn c sn xut trong qu trnh ch bin c sn. C hai loi sn:
sn ng v sn ngt khc nhau v hm lng tinh bt v xianua. Sn ng c nhiu
tinh bt hn nhng ng thi cng c nhiu axit xyanhydric, khong 200 300
mg/kg. Sn ngt c t axit xianhydric (HCN) v c dng lm lng thc, thc
phm. Sn trng cc tnh pha Bc ch yu l sn ngt v tinh bt thu c khng
c HCN.
Thnh phn ho hc ca tinh bt sn ph thuc ch yu vo trnh k thut
ch bin sn. Trong tinh bt sn thng c cc thnh phn sau:
Tinh bt : 83 88% [5]
Nc : 10,6 14,4%
Xenluloza : 0,1 0,3%
m : 0,1 0,4%
Cht khong : 0,1 0,6%
Hnh 2.1 Tinh bt sn [17] Cht ho tan : 0,1 1,3%

Tinh bt sn c kch thc x dch trong khong kh rng 5 40 m. Di
knh hin vi ta thy tinh bt sn c nhiu hnh dng khc nhau t hnh trn n hnh
bu dc tng t tinh bt khoai ty nhng khc tinh bt ng v tinh bt go ch
khng c hnh a gic.
Cng nh cc loi tinh bt khc tinh bt sn gm cc mch amilopectin v
amiloza, t l amilopectin v amiloza l 4:1. Nhit h ho ca tinh bt sn nm
trong khong 60 800C.
2.2. M chnh v axit glutamic
2.2.1 Tnh cht vt l [6]

Bt ngt (cn gi l m chnh) l mui mononatri ca axit glutamic hay nari

glutamat. d tan trong nc, thng gi l m chnh (bt ngt) c dng lm gia
v.
Axit glutamic thuc loi axit amin c cha mt nhm amin v hai nhm
cacboxyl. iu ch bng cch tng hp hoc ln men gluxit.
Axit L (+) - glutamic (thng gi axit glutamic) l nhng tinh th khng

mu, tonc = 247 - 249oC (phn hu), thng hoa 200oC, quay cc ring vi tia D
22oC: 31o. t tan trong nc, etanol; khng tan trong ete, axeton. ng vai tr
quan trng trong vic trao i m. Dng trong y hc, trong nghin cu sinh ho,
b sung vo khu phn thc n. Axit L (+) - glutamic c v ngt ca tht, cn axit D
() - glutamic khng c v .
Hnh 2.2 Cu trc phn t axit glutamic[18]

2.2.2.Vai tr ca axit glutamic [7]
Axit glutamic (cn gi l axit aminoglutaric) l hp cht ph bin nht
trong cc protein ca cc loi ht ng cc, nh trong prolamin ca cc ht u cha
43-46% axit ny. Axit glutamic ng vai r rt quan trng trong vic trao i cht
ca c th ng vt, nht l cc c quan no b, gan v c nng cho kh nng hot
ng ca c th. Axit glutamic tham gia phn ng thi loi amoniac, mt cht c
vi h thn kinh. Amoniac l cht thi trong qu trnh trao i cht. Axit glutamic

phn ng vi amoniac cho aminoaxit mi l glutamin. Trong y hc, axit glutamic

c dng nh thuc cha bnh yu c v chong.
2.3. Phng php sn xut axit glutamic:
C nhiu phng php sn xut axit glutamic, t cc ngun nguyn liu

khc nhau. Hin nay, trn th gii c bn phng php c bn
+ Phng php ho hc. [5, trang13]
Phng php ny ng dng cc phn ng tng hp ha hc tng hp nn

axit glutamic v cc amino axit khc t cc kh thi ca cng nghip du m hay
cc ngnh khc. Tuy nhin phng php ny yu cu k thut cao, vic tch L-axit
glutamic rt kh khn nn gi thnh sn phm cao.
+ Phng php thu phn. [5, trang 13]
Phng php ny s dng cc tc nhn l ha cht hoc enzyme thy

phn cc nguyn liu c hm lng protein cao, to ra hn hp cc amino axit trong
c axit glutamic. Sau tch axit glutamic ra khi hn hp bng phng php
ha l.
-u im: + Khng ch c qui trnh v cc iu kin sn xut.
+ C th p dng cc c s th cng, bn c gii ha.
+ n nh c cht lng sn phm ca tng m.
-Nhc im:
+ Nguyn liu s dng phi c hm lng protein cao
+ S dng nhiu thit b, ha cht, thit b chng n mn
+ Hiu sut thp dn n gi thnh cao.
+ Phng php kt hp [5, trang 15]

y l phng php kt hp gia ha hc v ln men.Vi phng php ny

hiu sut cao nhng n i hi k thut trang thit b hin i v chnh xc. V vy
phng php ny ch dng trong nghin cu.
+ Phng php ln men (sinh tng hp) [5, trang 14]
Ln men l phng php c s dng rng ri sn xut axit glutamic.
Phng php ny dng cc chng vi sinh vt c kh nng tng hp ra axit

glutamic sn xut.
- u im:
+ Nguyn liu r hn so vi hai phng php trn.
+ t s dng ho cht, thit b chng n mn.
+ Hiu sut qu trnh rt cao, gi thnh h.
+ C th s dng cc loi nguyn liu khc nhau .
+ To ra axit glutamic dng L, c hot tnh sinh hc cao.
- Nhc im:
+ Qu trnh i hi yu cu k thut cao v nghim ngt.
+ m bo v trng mi to sn phm.
+ Kh iu khin c qu trnh.
Sn xut axit glutamic bng phng php ln men ngi ta s dng 2

phng php l ln men 2 giai on (gin on) v ln men trc tip.
2.4.Chng vi sinh [20]
Tham gia vo qu trnh ln men sn xut axit glutamic, chng vi sinh thng
s dng l: Corynebacterium Glutamicum, Brevibacterium Lactofermentus,
Micrococus Glutamicus; nhng ch yu nht vn l chng Corynebacterium
Glutamicum (loi vi khun ny c nh vi sinh vt Nht Bn Kinosita pht hin

Hnh 2.3 Corynebacterium Glutamicum
t 1956, c kh nng ln men t tinh bt, ng, khoai, khoai m to ra axit

glutamic).
Ging vi khun thun khit ny c ly t ng thch nghing ti cc c s

gi ging, sau c cy truyn, nhn sinh khi
trong mi trng lng. Khi lng sinh khi c
nhn ln n yu cu ph hp cho quy trnh sn xut
i tr. Trc khi nhn, cy, mi trng lng phi
c thanh trng bng phng php Pasteur.
Chng vi khun ging phi c kh

Hnh 2.3 Corynebacterium Glutamicum
nng to ra nhiu axit glutamic, tc
sinh trng pht trin nhanh, c tnh n nh cao trong thi gian di, chu c
nng axit cao, mi trng nui cy n gin, d p dng trong thc t sn xut.
* C ch tng hp tha axit glutamic:
Tnh thm ca mng t bo b thay i v thiu biotin, do tc dng ca

penicillin hay dn xut ca cht bo. Nu tnh thm khng b thay i th ch din ra
s tng hp axit gutamic trong t bo v khng c s tit axit ny ra mi trng.
Nh vy, axit glutamic nng cao s c ch phn ng ca glutamate-
dehydrogenaza to thnh axit glutamic. Do bin i v tnh thm thu, t bo ch
cho axit glutamic ra ngoi v trong ni bo nng axit amin ny thp nn khng
c s c ch ngc bi sn phm cui cng. S h hi tnh thm xut hin khi nng
biotin ti u l 2 5 g/l. Cn nng bioin ti thch cho s sinh trng ca
chng khong 14 g/l. Cng c th to ra s h hi ny bng cch b sung cc
cht hot ng b mt nh Tween 60-polyoxyetylen- socbitanmonostearat, Tween-
40poyoxyetylen-sobitan-monopalmitat nh penicillin. Cc tc nhn b mt ny
c b sung vo gia hay cui pha sinh trng. Vic penicillin gy h hi cho tnh
thm c ngha thc tin c bit v nh c th s dng cc nguyn liu phc
tp nh r ng [4, tr 19].

2.5.Nhng yu t nh hng n qu trnh ln men [7]

2.5.1. pH ca mi trng
Cc chng vi khun sinh tng hp L-Glutamic u thch hp mi trng
trung tnh hay kim yu pH=6,7 8. Trong qu trnh ln men pH gim v to
ra axit glutamic v mt s axit hu c khc. Do phi iu chnh pH thng
xuyn bng NH+4. Ngun NH+4 s dng ph bin l ure, nc NH3, kh NH3,
NH+4Cl,
2.5.2.S cung cp O2
Ln men tng hp axit glutamic l qu trnh hiu kh bt buc. Do s
cung cp oxi trong khi ln men l ht sc quan trng. Nu thiu O2 th sn phm
ch yu l axit lactic, nu tha oxi th sn phm ch yu l axit --xetoglutaric. Oxi
c cung cp cho dch ln men bng cch sc khng kh v trng kt hp vi
khuy trn lin tc, vn tc cnh khuy 150 vng \pht.
2.5.3 Nhit
Nhit thch hp nht cho qu trnh ln men l 26-37oC, trong thc t ln
men giai on u 30-32oC v giai on cui 36-37oC.
2.5.4. Cht kch thch sinh trng
Qa trnh tng hp axit glutamic rt cn biotin. Biotin khng ch l cht sinh
trng m cn l cht xc nh thnh phn v s lng cc sn phm ln men. Sinh
khi ca vi khun tng t l vi hm lng biotin nhng vi axit glutamic th khng
hon ton nh vy: lng axit glutamic c to thnh nhiu nht khi trong mi
trng hm lng biotin thp hn nhiu so vi hm lng biotin cn thit cho s
pht trin ti a ca sinh khi. Biotin khng lm thay i hot lc ca cc enzim
tng hp nn axit glutamic m nh hng n tnh thm thu ca mng t bo, lm
cho axit glutamic t bn trong t bo vi sinh vt khuych tn ra ngoi mi trng
ln men. Nng biotin thch hp nht cho sinh tng hp axit glutamic 2-5g\l.
Ngun cung cp biotin l cao ng, r ng ma. Trong qu trnh ln men
nu dng r ng ma lm ngun cung cp ng v biotin th thng xy ra hin
tng tha biotin s khng c li, sinh tng hp axit glutamic t, nu sc kh km s

to ra alanin v axit lactic. V vy, ngi ta phi b sung thm penicilin km hm

s pht trin ca vi khun trong mi trng giu biotin ng thi tng trng qu
trnh tng hp axit glutamic.

CHNG III
CHN V THUYT MINH DY CHUYN
CNG NGH
3.1.Chn phng php sn xut [5]
Phng php ln men l phng php s dng rng ri hin nay sn xut
axit glutamic.
Nguyn tc: Dng chng vi sinh vt c kh nng tng hp ra axit glutamic
sn xut.
Sn xut axit glutamic bng phng php ln men ngi ta s dng 2 phng
php l ln men 2 giai on (gin on) v ln men 1 giai on (trc tip).
3.1.1. Phng php ln men gin on
Nguyn tc ca phng php ny l u tin to ra _Ketoglutaric bng cc k
thut vi sinh nh nui cy vi sinh vt. Sau , chuyn ho _Ketoglutaric thnh axit
glutamic nh enzyme aminotransferase v glutamatdehydrogenase.
Giai on chuyn t _Ketoglutaric thnh axit glutamic c th s dng nhiu
chng khc nhau nh Pseudomonas, Xantonomas, Ervinia, Bacillus, Micrococus.
Nhc im ca phng php ny l dng qu nhiu enzyme v axit amin lm
ngun amin cho phn ng dy chuyn nn t c dng trong cng nghip.
3.1.2. Phng php ln men trc tip
Nguyn tc ca phng php ny l sn xut axit glutamic ngay trong dch
nui cy bng mt loi vi sinh vt duy nht. Cc sinh vt ny u c h enzyme c
bit c th chuyn tip ng v NH3 thnh axit glutamic trong mi trng.
u im: + S dng ng lm nguyn liu c hiu sut cao.
+ Nguyn liu s dng r tin, d kim.
+ Nguyn liu cha y cc thnh phn dinh dng cho qu trnh
ln men.
T nhng nm 50 ca th k XIX, Nht Bn ch n phng php ln
men trc tip axit glutamic v t n nay sn phm ny hng nm vn ng u

trong cng nghip axit amin. Axit glutamic sn xut ch yu Nht Bn, chim 50
% sn lng th gii, ch yu bng phng php ln men trc tip.
Vi nhng u im nh vy, y ti chn phng php ln men mt giai
on sn xut acid glutamic
3.2.Quy trnh sn xut axit glutamic t tinh bt sn [2]
Tinh bt
Nc Pha long
Lc
to = 90-95 oC
t = 40 45 pht Dch ho Termamyl
H nhit (60-650C)
to = 60-65 oC
t = 70h ng ho _amylaza
K2HPO4 0,15%
MgSO4 0,075% Pha ch dch ln men (pH= 6,7-6,9)
MnSO4 0,0025%
Men ging
to = 125 oC Thanh trng v lm ngui
t = 15 pht
Ln men Chun b men ging
B sinh khi t bo Lc tch sinh khi
C c (Bx=30)
Ty mu Than hot tnh

p lc
H2SO4 Axt ho v kt tinh pH =3,22

to = 5 oC
Ly tm Dch sau ly tm
Lc ra
Sy
Lm ngui
Phn loi Bao gi

3.3 Thuyt minh quy trnh sn xut
3.3.1 Nguyn liu
Tinh bt sn l sn phm c ch bin t c sn. Trong tinh bt sn cha
83-88% hm lng tinh bt. Hn na, Vit Nam hin l nc ng th 3 v xut
khu tinh bt sn. V vy, tinh bt sn thch hp lm nguyn liu sn xut axit
glutamic
S dng xylo cha tinh bt.
3.3.2. Pha long, lc [1]
Pha long nhm lm trng n cc ht tinh bt v sau tin hnh lc nhm
loi b nhng cht cn b trong dch tinh bt trc khi thy phn.
Nng tinh bt ha tan khong 33- 40 %.
S dng thit b ho tan hnh tr, thp khng r, c cnh khuy.
Sau khi pha long, dung dch tinh bt c chy qua thit b lc hnh tr bn
trong l mng lc bng kim loi, t trong thng lc nhm lm sch tinh bt trc
khi a vo thy phn. S dng thng lc hnh tr, thp khng r, pha trn c mng
lc bng thp.

Hnh 3.1. Thit b ho tan tinh bt [21]
3.3.3.Dch ho [3]
Mc ch ca dch ha l chuyn h huyn ph cc ht tinh bt thnh dng dung
dch ha tan cha cc dextrin c chiu di mch ngn hn.
(C H O ) + nH O - amylaza, nC H O
6 10 5 n 2 6 12 6
Qu trnh dch ha bng enzym - amylaza c tin hnh t0 = 90-95,

pH = 5,5 7. Tn ch phm enzym - amylaza c s dng l Termamyl .
Thit b: Thc hin qu trnh dch ha trong cc ni phn ng 2 v, lm bng thp
khng g, thn hnh tr [6, tr 87].
Hinh 3.2.Thit b dch ho [23]

3.3.4.Lm ngui
Dch tinh bt sau khi dch ha c nhit khong 90 -950 C. Do , phi lm ngui
nhit dch tinh bt gim xung khong 60-650 C tin hnh qu trnh ng ha.

3.3.5.ng ho [3]
Mc ch ca ng ha l nhm chuyn dch dextrose thnh ng glucoza
ngun dinh dng m vi sinh vt ln men c th s dng c.
Dng emzym _amylaza thc hin qu trnh ny.
Cc thng s k thut ca qu trnh ng ha ny l: pH = 4,2 4,5; nhit 60
65oC, thi gian 70h. Thit b s dng cho qu trnh dch ha v ng ha l ni 2 v
lm bng thp khng g, c thn dng hnh tr
Hinh 3.3.Thit b ng ho[23]

3.3.6. Phi ch dch ln men [6]
Mc ch :To ra mi trng cho VSV s dng trong
qu trnh ln men to sinh khi.
Tin hnh: Phi trn gia dch thu phn tinh bt
v cc cht khong vo mi trng ln men theo bng
sau:[7]
Dch ng ho : 13%
K2HPO4 : 0,15%
MgSO4.7H2O : 0,075%
MnSO4 : 0,0025%
Hnh 3.4 Thit b pha ch [24]
Cao ng : 0,7%
iu chnh pH n :6,7 6,9
3.3.7 Thanh trng v lm ngui [7],[2]

Mc ch: Nhm v trng mi trng dinh dng trc khi ln men trnh
xm nhim ca vi sinh vt gy hi v sau h nhit ca mi trng dinh dng
xung nhit ln men thch hp vi vi sinh vt.
Hnh 3.5. Thit b thanh trng bn mng[25]
Tin hnh: dch c bm ngc chiu vi hi nc, to ra qu trnh trao i

nhit.
Thanh trng 125oC
Thi gian: 15 pht.
Sau khi thanh trng dch phi c h nhit 30 320C
Yu cu dch ln men phi v trng tuyt i.
Chn thit b thanh trng dng bn mng
3.3.8. Ging vi sinh vt [5]
Ging s dng l vi khun Corynebacterium glutamicum.
Mc ch l to ra s lng ging cn thit cho qu trnh ln men
3.3.8.1. Cy truyn ra ng thch nghing
-Mi trng thch nghing: [5]
Pepton : 1%
Cao th b : 1%
NaCl tinh ch : 0,5%
Thch : 2%

- Pha trn mi trng: Dng nc ho tan cc cht, cho thch vo sau cho
NaOH vo iu chnh pH = 7 7,2. Cui cng cho mi trng vo ng nghim
thanh trng 20 30 pht, p lc 1kg/cm2. Sau h nhit xung 50 600C,
ng nghim nghing thch ng li, sy 45 gi t0 = 320C, em bo qun lnh.
- Tin hnh : Dng que cy cy ging gc t cc ng thch nghing vo t
m trong 24 gi cho khun lc pht trin, ta c ging i 1, cy truyn sang ng
thch nghing mt ln na ta c ging i 2.
3.3.8.2. Ging cp 1
-Mi trng ging cp 1:[5]
ng glucoza tinh khit 2,5%
R ng 0,25%
Nc chm 0,32%
MgSO4.7H2O 0,04%
Fe, Mn ( pha 2000g/l) 0,002%
Ur 0,5%
B1 ( pha 150g/l) 0,00015%
- Chun b mi trng: Dng nc ho tan cc cht cho vo cc bnh tam gic
1000ml, sau iu chnh pH = 7 7,2, sau em i thanh trng 20 30 pht, p
lc 1kg/cm2, sau ngui xung 50 600C ri tin hnh cy ging.
-Tin hnh: Ging t cc ng thch nghing c cy vo cc bnh tam gic
sau a vo cc my lc trong 24 gi, sau bo qun lnh 50C.
3.3.8.3. Ging cp 2
- Mi trng cp 2 (thit b ln men 60 lt): [5]
ng glucoza 2000g
MgSO4 24g
H3PO4 60g
Nc chm 300ml
R ng 600g
Ur 480g

Du lc 60ml
B1 20mg
KOH pH = 9
- Chun b mi trng: Cc cht c ho trn cng vi nc sau thanh
trng 1200C trong thi gian 30 pht. Sau lm ngui xung cn 320C v tin
hnh ln men trong cc thit b ln men.
-Tin hnh: Qu trnh nui ging khng ch nhit 320C, p sut
1kG/cm3 khng tip ur v du nh qu trnh ln men chnh, lng khng kh cho
vo khong: 850 1100 lt/gi, kim tra pH 1 gi 1 ln hoc lng khng kh tng
dn tnh t ging nh sang ln men chnh theo t l 1,0 - 0,25 - 0,5l/l.pht: (lt
khng kh/lt mi trng /1 pht). n gi th 8 th soi chn ging: Ni no dng
c th 9 gi ging c th cy tip sang ni ln men chnh (o OD dch ln men,
soi nng vi khun v xc nh hm lng ng st) nu cha t yu cu th
c th ko di thi gian ln men thm 1 2h na.
Hnh 3.6: Thit b nhn ging cp II [26]
3.3.9. Ln men [7],[2]

Mc ch : Thng qua cc hot ng sng ca vi khun trong nhng iu kin
thch hp chuyn ho ng v m thnh acid glutamic. Nng dch ln men
1014%.

Tin hnh: Mi trng sau khi chun b v thanh trng xong c lm ngui
n nhit ln men v cy men ging vo vi t l 1% ln men. Thi gian ln
men 32-38h, nhit ln men 32-38oC. Trong qu trnh ln men phi cung cp
khng kh v trng lin tc, b sung thm ure iu chnh pH ca mi trng ln
men v phi khuy trn. Do mi trng ln men to nn axit glutamic cng vi
thnh phn ca mi trng c xu hng lm tng sc cng b mt. V vy, trong
qu trnh ln men to thnh nhiu bt nh hng n qu trnh sinh tng hp nn
phi s dng cht ph bt.
Trong qu trnh ln men, ng c b sung lin tc v t ng khi nng
oxi ha tan hoc pH gim. Nng ng b sung t 38 45% [2].
Hnh 3.7: Thit b ln men [28]

3.3.10. Lc
Mc ch: loi xc t bo vi khun sau qu trnh ln men.
Dung dch sau ln men c lc bng thit b lc khung bn.

Hnh 3.8. H thng lc khung bn [27]
3.3.11. C c [2]
Dch sau ln men c nng axit glutamic khong 17 %, s a qua h thng c

c chn khng to dung dch axit glutamic c nng khong 30%
Hnh 3.9. Thit b c c chn khng [12]
3.3.12. Ty mu
Mc ch: Dng than hot tnh hp th nhng cht mu, tp cht c sinh ra
trong qu trnh ln men.
Dng thit b ty mu c ct than hot tnh c nh v cho dung dch cn ty di
qua ct.
3.3.13. p lc.

Sau khi ty mu cn cho vo thit b p lc lm trong dung dch. S dng thit

b lc khung bn.
3.3.14. Axt ho v kt tinh [5]
Mc ch: chuyn axit glutamic t pha lng sang pha rn tinh th.
Axit ha axit glutamic: Ton b dung dch axit glutamic thu c trn c a
v thng kt tinh. Cho cnh khuy hot ng lin tc ngn nga axit glutamic kt ta
qu sm, kt tinh nh v hiu qu thp. Cho H2SO4 98% vo to im ng in PH
= 3,22 th thi v bt u lm lnh.
Lm lnh v kt tinh: dch axit glutamic sau khi t pH ng in th cho nc
lnh khong 50C vo v thng v lm lnh. Trong qu trnh ny cnh khuy hot ng
lin tc lm cho axit glutamic kt tinh xp v ti, sau t nht 48 gi th qu trnh kt tinh
kt thc.
3.3.15. Ly tm [2]
Hnh 3.10. Thit b kt tinh[29]
Mc ch tch pha rn v lng :
- Pha rn: gm axit glutamic kt tinh v lng xung, thu c axit
glutamic m.
- Pha lng: gm nc v mt t axit glutamic khng kt tinh ha tan vo ta
gi l nc ci. Phn nc ci a i kt tinh li.

3.3.16. Lc
Tinh th sau khi ly tm cn m v c bm mu nu nn cn c lm sch
bng qu trnh p lc.
Hnh 3.12. Thit b lc [32]
3.3.17. Sy
Mc ch : Axit glutamic ht m rt nhanh nn sau ly tm phi sy ngay.
Tin hnh : Axit glutamic m a vo thit b sy nh c cu rung v chy
trn bng chuyn lin tc, khng kh nng c thi lin tc vo lm bay hi m v
lm kh acid.

Hnh 3.13. Thit b sy rung tng si [33]
3.3.18. Lm ngui
Tinh th axit glutamic c lm ngui trn bng ti lm ngui trc khi bao
gi.
3.3.19. Phn loi
Axit glutamic sau khi sy c cho qua sng rung phn loi phn loi ht
trc khi a vo ng gi.
Hnh 3.14 My phn loi XZS [33]
3.3.20. Bao gi [2]

Mc ch: To sn phm hon chnh, m bo sn phm c th c bo qun
trong mt thi gian nht nh m khng nh hng n ch tiu v cht lng, v
sinh an ton thc phm.
Tin hnh: Axit glutamic sau khi lm ngui c a vo my ng gi trong
cc ti 0,5 kg. gia ti c ghi nhn hiu, khi tnh lng, ngy sn xut, hn s

dng v cch s dng. Cc ti axit glutamic nh 0,5kg c bc trong 1 ti ln

khong 10 kg c bc bng giy chng m v ng hp carton a qua nhp kho
[16].
Hnh 3.15. Thit b bao gi ng TTM-1300KB [33]

CHNG IV
CN BNG VT CHT
4.1 Chn cc s liu ban u

Nng sut ca nh my: 4570 tn sn phm/nm
Nguyn liu dng: tinh bt.
Ta gi s tn hao ca tng cng on so vi cng on trc nh sau:
Pha long,lc 0,5%
Dch ho 2%
ng ho 2%
Pha ch dch ln men 1%
Thanh trng v lm ngui 1%
Ln men 2%
Lc 2%
C c 1%
Ty mu 1%
Axt ho v kt tinh 1,5%
Ly tm 2%
Lc 1,5%
Sy 1%
Phn loi 0,5%
Lm ngui v bao gi 1%
4.2. Biu sn xut
Nh my lm vic mt nm 12 thng, mt ngy lm 3 ca. Mi ca 8 gi.

Trong c thng 11 l ngh 10 ngy v sinh v bo dng thit b sn xut, 10
ngy ngh do s c k thut v 4 ngy ngh tt m lch.
Ta c tng kt thi gian sn xut ca nh my trong mt nm nh sau:

S ngy lm vic trong nm: 365 24 = 341 ngy.
S ca lm vic trong nm: 341 3 = 1023 ca.
4.3 Cn bng vt liu

Nh my sn xut axit glutamic tinh th vi nng sut 4570 tn/nm. Nh
vy nng sut mi ngy ca nh my l:
maxit glutamic = 4570 : 341 = 13,4 tn/ngy = 13400 kg/ngy
4.3.1.Lm ngui v bao gi

T l hao ht l 1%
Lng axit glutamic trc khi bao gi l:
100
13400 = 13535,35 (kg/ngy)
100 1
4.3.2. Phn loi
T l hao ht ca cng on ny l 0,5%
Lng axit glutamic thu c trc khi phn loi l:
100
13535,35 = 13603,37 (kg/ngy)
100 0,5
4.3.3. Sy
T l hao ht l 1%
Gi s tinh th axit glutamic c m trc v sau khi sy ln lt l:
m trc khi sy l 3%
m sau khi sy l 0,4%
Lng tinh th axit glutamic m em sy l:
100 100 0,4
13603,37 = 14109 (kg/ngy)
100 1 100 3
4.3.4. Lc ra
T l hao ht l 1,5%
Gi s m ca axit glutamic trc khi lc l 8%.
m sau khi lc l 3%

Lng axit glutamic trc khi tin hnh lc l:

100 100 3
14109 = 15102,42 (kg/ngy)
100 1,5 100 8
4.3.5. Ly tm
T l hao ht ca cng on ny 2%
Khi lng axit glutamic trc khi ly tm tnh hao ht l:
100
15102,42 = 15410,63 (kg/ngy)
100 2
Gi s m ca axit glutamic trc khi ly tm l 11%.
m sau khi ly tm l 8%
Lng axit glutamic trc khi ly tm l:
100 8
15410,63 = 15930 (kg/ngy)
100 11
4.3.6. Axit ha, kt tinh
T l hao ht l 1,5%.
m trc li tm 11%, tc m sau kt tinh l 11%.
Nng axit glutamic trc kt tinh 30% . [ 2]
Lng axit glutamic m sau kt tinh c tnh tn tht:
100 100 11
15930 = 47978,95 (kg/ngy).
(100 1,5) 100 70
4.3.7.Lc p
T l hao ht ca qu trnh ny l 0,5%
Lng axit glutamic trc khi hao ht l
100
47978,95 = 48220,05 (kg/ngy)
100 0,5
4.3.8. Ty mu
T l hao ht ca cng on ny l 1%
Khi lng dch axit glutamic trc khi ty mu l:
100
48220,05 = 48707,12 (kg/ngy)
100 1

4.3.9. C c chn khng

T l hao ht 1%
Sau khi c c nng axit glutamic l 30% nn lng axit glutamic to
thnh l:
30
48707,12 = 14612,136 (kg/ngy)
100
Nng axit glutamic trong dung dch a i c c l l7% nn lng dch a i
c c l:
100 100
14612,136 = 86875,43 (kg/ngy)
100 1 17
4.3.10. Lc tch s b
T l hao ht ca cng on ny l 2%
Khi lng dch axit sau khi hao ht l:
100
86875,43 = 88648,39 (kg/ngy)
100 2
4.3.11. Ln men
T l hao ht l 2%
Lng dch trc ln men:
100
88648,39 = 90457,54 (kg/ngy)
100 2
T trng ca dch l d=1035,049 kg/m3, [12] suy ra th tch dch ln men l:
90457,54 3
V = = 87,39 (m /ngy)
1035,049
Lng ging cho vo ln men l 5% th tch dch mi trng. Vy lng
5
ging cho vo l Vging = 87,39 = 4,37 (m3/ngy).
100
Ging c khi lng ring l 1070 (kg/m3). Khi khi lng ging cho vo
l: mging = 4,371070=4675,9 (kg/ngy)
Lng ging cp II bng 10% lng ging ln men
Vging cp II = 10% 4,37 =0,437 (m3/ngy).
mging cp II = 1070 0,437 = 467,59 (kg/ngy).

Lng ging cp I bng 10% lng ging cp II

Vging cp I = 10% 0,437 = 0,0437 (m3/ngy).
mging cpI = 1070 0,0437= 46,759 (kg/ngy).
Khi lng mi trng em i ln men l:
90457,54 4675,9 = 85781,64 (kg/ngy)
4.3.12. Thanh trng v lm ngui
Gi s t l hao ht ca cng on ny l 1%
Lng mi trng trc khi tin hnh qu trnh l:
100
85781,64 = 86648,12 (kg/ngy).
100 1
4.3.13. Pha ch dch ln men
Gi s t l hao ht ca cng on ny l 1%
Lng mi trng trc khi xy ra hao ht l:
100
86648,12 = 87523,35 (kg/ngy).
100 1
4.3.14. ng ha
Lng axit glutamic c trong dch sau khi ln men l:
17
88648,39 = 15070,22 (kg/ngy).
100
Theo phng trnh ln men, ta c:
3
C6H12O6 + O2 + NH3 C5H9NO4 + CO2 +3H2O
2
180 147
Hm lng ng to thnh axit glutamic l:
180
15070,22 = 18453,3 (kg/ngy)
147
Chn lng ng hao ht trong qu trnh ln men 2%, phi ch 1% th lng
ng cn c:
100 100
18453,3 = 19020,09 (kg/ngy)
100 2 100 1
T l hao ht l 2%

Chn nng ca tinh bt l 40%.

Phn ng thy phn:
(C6H10O5)n + n H2O n C6H12O6
162n 180n
Hm lng tinh bt sn ban u l:
162
19020,09 = 17118,081 (kg/ngy).
180
Lng tinh bt trc khi ng ha l:
100 100
mtinh bt= 17118,081 = 43668,57 (kg/ngy)
100 2 40
4.3.15. Dch ha
T l hao ht l 2%
100
mtinh bt= 43668,57 = 44559,76 (kg/ngy)
100 2
4.3.16. Pha long,lc
T l hao ht l 0,5%.
Lng dch tinh bt trc khi vo lc l:
100
mtinh bt= 44559,76 = 44783,67 (kg/ngy)
100 0,5

4.4. Tng kt
Bng 4.1. Bng tng kt khi lng qua cc cng on
Khi lng
STT Cng on (kg/ng
(kg/ca) (kg/h)
y)
1 Tinh bt ban u 17118,081 5706,027 713,25
2 Pha long,lc 86875,43 28958,48 3619,81
3 Dch ha 88648,39 29549,46 3693,683
4 ng ha 90457,54 30152,51 3769,064
5 Pha ch dch ln men 86648,12 28882,71 3610,338
Thanh trng v lm
6
ngui 87523,35 29174,45 3646,806
7 Ln men 43668,57 14556,19 1819,524
8 Lc tch s b 44559,76 14853,25 1856,657
9 C c chn khng 44783,67 14927,89 1865,986
10 Ty mu 48707,12 16235,707 2029,46
11 Lc p 48220,05 16073,35 2009,16
12 Axit ha, kt tinh 47978,95 15992,983 1999,12
13 Ly tm 15930 5310 663,75
14 Lc ra 15102,42 5034,14 629,26
15 Sy 14109 4703 587,875
16 Phn loi 13603,37 4534,45 566,8
17 Bao gi 13535,35 4511,78 563,97

CHNG V
TNH V CHN THIT B
5.1. Xylo cha tinh bt:
Xylo c th tch cha nguyn liu sn xut mt gi, c dng hnh tr,
y hnh nn c gc nghing =600, c ch to bng thp. Chn h s cha y
=0,8.
m
Th tch xylo: V = VT + VN =

Trong , V: th tch xylo, m3 h2 D
VT: th tch phn hnh tr, m3
V: th tch phn hnh nn, m3
m: khi lng nguyn liu cn x l, kg 600
: khi lng ring ca nguyn liu, kg/m3 h1
h2 h1 D 2 d 2 D d
V = D 2 + ( + + ) (1) h d
4 3 4 4 2 2
Dd
M h1 = tg . Chn h2 = 1,3D v d = 0,2 m,
2
h = 0,2 m
T (1) ta c kt qu:
29,94 D 3 0,043
V = (2)
24
Tinh bt cn trong 1ca : 57026,027 (kg).
Ga s tinh bt c m l 10% th khi lng tinh bt l:
100
m= 57026,027 = 57083,1 (kg).
100 0,1
Khi lng ring ca tinh bt sn: d = 1570 (kg/m3). [35]
Th tch ca nguyn liu tinh bt:
m 57083,1
Vtinh bt = = = 36,35 (m3).
d 1570

Chn h s cha y: = 0,8

Th tch xylo cha:
36,35
Vthit b = = 45,45 (m3).
0,8
29,94 D 3 0,043
T (2) V = = 45,45
24
D = 3,3
ng knh xylo cha: D = 3,3 m.

ng knh ng tho liu: d = 0,2 m.
Chiu cao ng tho liu: h = 0,2 m.
Chiu cao thn xylo: h2 = 1,3D = 4,29 m.
Dd
Chiu cao chp: h1 = tg = 2,68 m.
2
Chiu cao xylo: H = h2 + h1 + h = 4,29+ 2,68 + 0,2 = 7,17 ( m).
S xylo cha: 1 xylo cha.
5.2. Thit b ha tan
Thit b ha tan c ch to bng thp khng g, thn hnh tr, y v np hnh

chm cu.
Gi h1 l chiu cao hnh tr, h l chiu cao np v y
Chn h1 = 1,6D; h = 0,1D.
Th tch hnh hc thit b: Vtb = Vtr + 2Vcc
Th tch hnh tr:
D 2 h1 D 2 1,6 D
Vtr = = = 0,4D 3
4 4 h
D
Th tch chm cu: h1
2 3
3D 19D
Vcc = h( h 2 + )=
6 4 1500
Th tch thit b:
19D 3 159,5 3
Vtb = Vtr + 2Vchm cu = 0,4D 3 + 2 = D
1500 375

Vtb 375
D=3
159,5
Gi s mt m ha tan trong 25 pht.
Khi lng ring tinh bt sn: d = 1570 (kg/m3) = 1,57 (kg/l). [20]
Khi lng ring dch tinh bt sn 40 % :1,228 (kg/l).
Theo bng (4.2), thng ho tan phi cha lng dch tinh bt sn ha tan
trong 1 gi:1865,98 (kg/h).
Th tch dch ha tan trong 1 gi:
1865,98
= 1519,53(l/h).
1,228
Chn h s cha y thit b: = 0,8.

Th tch ca thit b:
1519,53 25 3
VTb = = 791,42 (l) 0,79 (m )
0,8 60
0,79 375
D=3 = 0,84 (m).
159,5
h1 = 1,6D = 1,6 0,84= 1,344 (m).
h = 0,1D = 0,1 0,84 = 0,084 (m).
Chiu cao ton b thit b: H = h1 + 2h = 1,344 + 2 0,084 = 1,512 (m).
S thit b ha tan:1 thit b.
5.3. Thit b dch ha
Thit b dch ha l thit b 2 v c th chu c axit v nhit [5, tr 87].
Khi lng ring dch tinh bt sn 40 %:1,228 (kg/l).
Th tch tinh bt cn c dch ha l:
1856,65
Vtinh bt = = 1511,9 (l/h).
1,228
Chn thit b dch ha PZG-2000
c tnh k thut ca thit b: [23]

+ Th tch cha ,l: 2000
+ p sut trong ni: <0,1
+ p sut ngoi v: <0,1
+Din tch trao i nhit (m2) 5
+Kch thc thit b: 1,21,5
45
Thi gian dch ha l 45 pht nn s thit b l = 0,75
60
Vy s thit b dch ha l 1 thit b.
5.4. Thit b ng ha
14556,19
Th tch tinh bt ng ha l: Vtinh bt = = 11853,57 (l/ca).
1,228
Chn thit b dch ha PZG-12000 [23]
c tnh k thut ca thit b:
+ Th tch cha ,l: 12000
+ p sut trong ni: <0,1
+ p sut ngoi v: <0,1
+Kch thc thit b: 1,83,5
70
Thi gian ng ha l 70h nn s thit b l = 8,75
8
Vy s thit b ng ha l 9 thit b.
5.5. Thng pha ch dch ln men:
Chn thng c dng hnh tr ng, v thng c lm bng thp khng g.

Bn trong c cnh khuy, np v y hnh chm cu.

Tinh bt sau khi ng ha v pha ch dch ln men c nng sut 3646,8 (kg/h).
Khi lng ring dch ng (14%) lc ny l:
dich = 1039,98 (kg/m3). [12,trang 58]
Th tch ca dch lc ny l:
m dich 3646,8
Vdch = = = 3,5 (m3).
dich 1039,98
Chn h s cha y l = 0,8
Ta c th tch ca thng cha l:
V dich 3,5
Vtbi = = = 4,38(m3).
0,8
Vthit b = Vtr + 2Vcc
Vtr : l phn th tch hnh tr
Vcc : l phn th tch hnh chm cu
Gi h1 l chiu cao hnh tr, h2 l chiu cao np v y

h
Chn h1 = 1,6D; h2 = 0,1D. D
h
Th tch hnh hc thit b: Vtb = Vtr + 2Vcc
Th tch hnh tr:

h
D 2 h1 D 2 1,6 D
Vtr = = = 0,4D 3
4 4
Th tch chm cu:
3D 2
Vcc = h2 (h22 + ) = 0,025D 3
6 4
Th tch thit b:
3 3 3
Vtb = Vtr + 2Vchm cu = 0,4D + 2 0,025 D = 0,45D

Vtb 4,38
D=3 = 3 = 1,45(m)
0,45 0,45
Suy ra: h1 = 1,6D = 1,6 1,45 = 2,32(m).
h2 = 0,1D = 0,1 1,45 = 0,145 (m).
Chiu cao ton b thit b: H = h1 + 2h2 = 2,32 + 2 0,145 = 2,61 (m)
Vy chn thit b pha ch c kch thc sau:
D = 1,45 (m); H = 2,61(m).
5.6. Thit b thanh trng v lm ngui:
3610,3
Th tch dch em thanh trng V= = 3,47(m3/h)
1039,98
Chn 1 thit b thanh trng dng tm:
c tnh k thut ca thit b tm dng truyn nhit BR4: [14]
+ Lu lng cc i, m3/h: 5
+ S lng tm truyn nhit: 143
+ B dy tm truyn nhit,mm: 0.3mm
+ Kch thc thit b, mm: 18707001400
+Khi lng: (kg) 900
15,47
S lng thit b n= =0,77. Ta chn 1 thit b.
20
5.7.Thit b nhn ging cp I:
Lng ging cp I bng 10% lng ging cp II [4,trang 119]
Vging cp I = 0,0437 (m3/ngy)=1,82 (l/h)
H s cha y = 0,75
Th tch ca thit b nhn ging l:

1,82
Vthit b = = 2,42(l)
0,75
Chn bnh tam gic thy tinh nh c th tch 1000ml lm thit b nhn ging
cp I.
Thi gian nhn ging cp 1 l t 18h
S bnh tam gic cn cho mt ngy vic l:
18
n = 2,42 =1,82 bnh. Ta chn 2 bnh tam gic.
24
5.8. Thit b nhn ging cp II:

Th tch ging cp hai cn nhn trong mt ngy l 0,437 (m3/ngy).
Vcp II = 0,437 (m3/ngy)
Chn h s cha y = 0,6
0,437
Vthit b = = 0,72 (m3)
0,6
Nhn ging cp hai c thc hin trong cc ni ln men c dng hnh tr, np v
y hnh chm cu.
Tnh ton nh mc 5.5, ta c:
Vtb 0,72
D=3 = 3 = 0,79(m)
0,45 0,45
Suy ra: h1 = 1,6D = 1,6 0,79 = 1,264(m).
h2 = 0,1D = 0,1 0,79 = 0,079 (m).
Chiu cao ton b thit b: H = h1 + 2h2 = 1,264 + 2 0,079 = 1,422 (m)
Vy chn thit b ln men c kch thc sau:
D = 0,79 (m); H = 1,422(m).
Thi gian nhn ging cp II l 9h

Vy s thit b l:1 thit b
5.9.Thit b nhn ging cp III
Th tch ging cp ba cn nhn trong mt ngy l 4,37 (m3/ngy).
Vcp III = 4,37 (m3/ngy)
Chn h s cha y = 0,6
4,37
Vthit b = = 7,28 (m3)
0,6
Thit k ni ln men nhn ging cp III tng t nh ni nhn ging cp

II.
Tnh ton tng t nh mc 5.5 ta c:
D = 1,72 (m); H = 3,302(m)
Thi gian nhn ging sn xut l 9h [5 - tr 173].
S thit b nhn ging cp III l: 1 thit b .
5.10. Thit b ln men
Qu trnh ln men c thc hin gin on trong cc thit b ln men theo

tng ca sn xut. Tng thi gian tin hnh ln men l 30h.
Tng th tch dch ln men trong mt ca l .
m dich 30152,5
Vdch = = = 29,1(m3).
dich 1035,049
Chn h s cha y ca thit b ln men l = 0,8
Th tch ca thit b ln men:
29,1 3
Vthit b = = 36,4 (m ).
0,8

Chn thit b ln men model FXG 60.0
Thng s k thut thit b [28]
Nng sut thit b (m3) :50
ng knh (mm) :3100
Chiu cao (mm) :8550
p sut thit k trong tank (Mpa) :0,2
p sut thit k trong o lnh (MPa) :0,3
S lng cnh khuy :2
Tc o trn (vng/pht) :<110
Cng sut ng c (KW) :55
Kiu truyn nhit : o lnh / ng trao i nhit
Thi gian ln men mt m l 30h. Thit b ta tnh cho mt ca 8h. S thit b cn

30
chn quay vng cho m ln men l: = 3,75
8
Vy ta chn 4 thit b ln men
5.11. Thit b lc ra
Nng sut ca dch lc 3693,68 (kg/h)
Khi lng ring ca dch ln men xong (axit glutamic 17%) l 1063,4
3
(kg/m )
Th tch ca dch lc l
3693,68
Vdch lc = = 3,47( m3/h)
1063,4
B9 BC
Chn thit b lc: vi cc thng s k thut sau:
423 53 00 00
- Nng sut : 9 m3/h [14]
- Din tch b mt lc : 19,5 m2

- S lng bn lc : 60 ci
- Kch thc bn : 565 575 mm
- p sut lm vic : 2,5 kg/cm2
- Cng sut ng c in : 4,5 kW
- Kch thc thit b : (2.500 1.080 1.470) mm
- Khi lng : 1.470 kg.
3,47
S thit b: = 0,38 . Vy ta chn 1 thit b
9
5.12.Thit b c c
Theo bng 4.2, lng axit glutamic a i c c: 3619,8 (kg/h).

Lng axit glutamic sau c c:2029,46 (kg/h).
Lng hi nc bay hi:
3619,8 2029,46 = 1590,34 (kg/h).
Ta chn thit b c c chn khng WZ-2000 . [12]
Thng s chnh ca thit b:
Nng sut bay hi (kg/h) 2000
p lc hi (MPa) <0,1.
chn khng (MPa) -0,06 -0,08
Cng sut in (Kw) 9,3
Din tch trao i nhit (m2) 15
Kch thc( m) 3,2 0,9 3,8
535 , 4
S thit b cho qu trnh c c l =0,53
1000
Vy chn 1 thit b c c
5.13. Thit b ty mu:
Lng dung dch axit glutamic a i ty mu: 2029,46 (kg/h).
Gi s thi gian lu 30 pht, lng than hot tnh chim 1/3 th tch thit b.
Khi lng ring axit glutamic 30% :1,186 (kg/l)

Th tch dung dch axit glutamic

h
2029,46
= 1711,18(l). D
1,186 h1
H s cha y ca thit b l 0,8.

Th tch thit b cn thit k: h
1711,18 30 3 3
= 1604,23(l).= 1,6 (m )
0,8 60 2
Tnh ton nh mc 5.5, ta c:
D= 1,06 (m).
H = 1,908(m).
S thit b ty mu : 1 thit b
5.14. Thit b kt tinh:
Thit b kt tinh c cnh khuy. C thn hnh tr trn, np v y hnh chp

cu. Thit b lm vic gin on.
Lng dch em kt tinh cho 1 ca l 15992,983(kg/ca)
Khi lng ring ca axit glutamic l 1162 (kg/m3)
Th tch ca dch l:
15992,983
=13,76(m3/ca)
1162
Chn h s cha y l 0,8
13,76
Th tch ca thit b l: =17,2(m3)
0,8
Chn thit b nhit hai v dung tch 30000L.
Thng s k thut: [29]
Th tch (L) :30000
Th tch thc t (L) :32710

Din tch truyn nhit (m2) :34,2
ng knh thit b (mm) : 2900
Chiu cao thit b (mm) :4385
Tng chiu cao thit b (mm) :7250
Khi lng thit b (kg) :19800
Thi gian kt tinh l 48h.
48
Nn s thit b cho qu trnh kt tinh l = 6 thit b.
8
5.15.Thit b ly tm
Khi lng dung dch axit glutamic trc khi vo my ly tm l 663,75kg/h
Chn thi gian ly tm l 20 pht.
Lng dung dch axit glutamic ly tm c trong 1 m.
20
m= 663,75 =221,25kg.
60
Th tch axit glutamic ly tm trong 1 m.
221,25
V= =0,19(m3)
1162
H s cha y ca thit b l 0,8
Th tch ca thit b:
0,19
V= =0,238m3
0,8
Chn my li tm DSD 250SL
Thng s k thut: [30]
+ Nng sut ca thit b, m3/h 2
+ S vng quay ln nht ca roto, v/p 5000

+ Cng sut ng c, kW: 15
+ Kch thc c bn, mm: 20001200700
+ Khi lng, kg: 900
S thit b ly tm:
0,238
n= = 0,119 . Vy ta chn s thit b ly tm l 1.
2
5.16. Thit b lc
Lng dch axit glutamic em lc l 629,26 (kg/h).
Th tch dch lc:
629,26
V= = 0,541 (m3/h)
1162
Chn thit b lc belt filter model: DY1000-Q
Thng s k thut: [32]
Chiu rng li lc, mm : 1000
Vt liu lm li lc :Polyester
Tc li lc :0,8-5,5 m/pht
Cng sut (KW) :1,5
Nng lc lc ra :4m3/h
Kch thc (mm) :514016502230
Khi lng (kg) :4800
0,3
S thit b lc n= = 0,07, ta chn 1 thit b lc.
4
5.17. Sy rung tng si

Chn thit b sy rung tng si sy tinh th axit glutamic v thit b c kh

nng lm vic lin tc.
Khi lng axit glutamic cn c sy l: maxit glutamic =587,875kg/h
m trc khi sy l 3% v sau khi sy l 0,4%.
Model my: ZLG 0,334,5 [33]
Trng lng:1560 (kg).
Bng 5.1
Nhit Nng sut

B mt sy Nhit Kchthc (mm)
kh vo bay hi
(m2) 0
kh ra (0C) (LWH)
( C) (kg/h)
1,35 80 40 535 485013501650
5.18.Thit b phn loi
Khi lng axit glutamic cn phn loi l:566,8 (kg/h)
Chn my sng rung ZS800
Thng s k thut: [33]
Nng sut (kg/h) : 1000
Kch thc sng : 5-200mesh
Cng sut : 0.75kw
Tn s rung : 1500 ln/pht
Trng lng : 480kg
Kch thc : 1.211.4m
566,8
S thit b phn loi: n= = 0,23 . Ta chn 1 thit b
2500

5.19.Thit b ng gi
Trng lng ng gi l: 500 g.
Nng sut ng gi trong 1 gi l:
563,97
563,97 (kg/h) 1127,94 ( gi/h)
0,5
My ng ti DXD-1300KB
Thng s k thut chnh: [33]
Nng sut: 10-30 ti/pht
Phm vi ng gi: 100-1000g
chnh xc ng gi Sai s 2%
Tiu hao kh nn : 0,6Mpa 300L/ pht
Cng sut in : 3KW
in p : 220V
Kch thc my 800 x 700 x 2100 mm
Kiu hn ti Hn kiu gi
1127,94
S thit b ng gi n= =0,62.
30 60
Ta chn s thit b l 1 thit b.
5.20. Chn gu ti
Lng tinh bt cn ti ln cyclon cha bng lng tinh bt bng ti chuyn

i ho tan l 1865,98(kg/h).
Mt xp ca vt liu l 500 (kg/m3).
Ta chn cc thng s sau:
Dung tch ca gu :V = 0,9 lt.

Bc gu :L = 250 mm.
Chiu rng tm bng :B = 150 mm.
Chiu rng ca gu :b = 110 mm.
Chiu cao ca gu :h = 132 mm.
Chiu cao ming gu : h1 = 66 mm.
Gc nghing ca thnh gu l : = 40.
Gc ln ca y gu l :r = 35 mm.
Kch thc gu ti 5007005500 mm.
Nng sut ca gu ti tinh theo cng thc:
V v KZ
Q = 3,6
L
Cng sut truyn ng ca tang dn:
QHg
N=
1000
Trong
g: Gia tc ri t do, chn g = 9,81 m/s2.
: H s hu dng, chn = 0,8.
Chn vn tc v = 0,2 m/s.
0,9 0,2 500 0,85

Q = 3,6 = 1,2 (tn/h).
0,25 1000
1,1 5 9,81
N= = 0,067 (kW)
1000 0,8
5.21. Chn bm
Trong nh my s dng ch yu l bm ly tm
Chn bm cho cng on x l nguyn liu l:

1,519
Th tch ca dch tinh bt cn bm l: V = = 0,18 m3/h
8
Chn bm c hiu l BH-5 bm nguyn liu tinh bt trong nh my
Thng s k thut nh sau: [14 trang 372]
+ Nng sut, m3/h: 5
+ p sut, MPa: 0,08
+ Tc quay, vng/pht: 1420
+ Cng sut ng c, kW: 1,7
+ ng knh ng ht/y, mm: 36/36
+ Kch thc, mm: 432290285
+ Khi lng, kg: 29,3
Chn bm cho cng on x l axit glutamic l:
Th tch ca dch ln men sau khi pha ch cn c bm l:
9,49 3
V= = 0,43 m /h
8
Chn bm c hiu l BH-5 bm dch ln men sau khi pha ch.

Bng 5.2 Bng tng kt tnh v chn thit b
STT Tn thit b Kch thc(m) S tb

1 Cyclo cha tinh bt D =3,3 ; H =7,17 1
Thit b ha tan v
1 D =0,84; H =1,512 1
lc
2 Thit b dch ha 1,21,5 1
3 Thit b ng ha 1,83,5 9
Thit b pha ch
4 D = 1,45; H = 2,61 1
dch ln men
Thit b thanh trng
5 1870 700 1400 1
v lm ngui
6 Thit b ln men D = 3100; H =8550 4
Lc tch t bo vi
7 2,5 1,08 1,47 1
khun
8 C c chn khng 3,2 0,9 3,8 1
9 Ty mu D = 1,06; h = 1,908 1
10 Axit ha, kt tinh D = 2,9; h = 4,385 6
11 Ly tm 21,20,7 1
12 Lc bng ti 5,11,62,2 1
13 Sy bng ti 215515503110 1
14 Phn loi 1.211.4 1
15 My bao gi 0,8 x 0,7 x 2,1 1
Gu ti vn chuyn
16 0,5000,75,5 2
tinh bt
Bm x l nguyn
17 0,432 x 0,29 x 0,285
liu
Bm x l axit
18 1,307 x 0,38 x 0,74
glutamic
Thit b nhn ging
19 D = 1,72; H = 3,302 1
c p 3
Thit b nhn ging
20 D = 0,79; H =1,42 1
c p 2
5.22.Thng cha
Cc thng cha l cc thng hnh tr trn, np v y bng.

Cc thng cha c tnh theo cng thc:
D 2 H
Vtbi =
4
Bng 5.3 Bng tng kt cc thng cha
STT Cng on Kch thc

1 Thng cha sau thanh trng v D=2; H=1,35
lm ngui
2 Thng cha sau lc D=1,6; H=2,1
3 Thng cha sau lc(cha b) D=0,5; H=1,2
4 Thng cha sau c c D=1,5; H=1,2
5 Thng cha sau ty mu D=1,5;H=1,2
6 Thng cha sau p lc D=1,5; H=1,2
7 Thng cha sau kt tinh D=1; H=0,9
8 Thng sau khi ly tm(cha mt) D=0,5; H=1,5

CHNG VI
TNH T CHC V XY DNG
-- --
6.1.Tnh t chc:
6.1 S h thng t chc ca nh my.
GIM C
PG KINH DOANH PG K THUT
T y Phng Phng Phng Phng Phng Phng

t, maketing hnh k k k KCS
b o chnh ton, hoch thut
v ti v
Kho Phn xng Phn xng Phn xng c

ph tr sn xut in
6.1.2.T chc lao ng ca nh my:
6.1.2.1.Ch lm vic:
Nh my sn xut axit glutamic, nng sut 4570tn sp/nm hot ng lin

tc, khng k ngy l, th 7 v ch nht. Trong thng 11 l ngh 20 ngy v
sinh v bo dng thit b sn xut v 4 ngy ngh tt m lch (Theo 4.1).
Theo 4.1, s ngy nh my sn xut l 341 ngy/nm.
Mi ngy phn xng sn xut lm vic 3 ca.

- Ca 1 t 6h-14h.
- Ca 2 t 14h-22h.
- Ca 3 t 22h-6h sng hm sau.
Khi hnh chnh lm vic 8h/ngy.
- Sng t 7h30-11h30.
- Chiu t 1h30-5h30.
6.1.2.2. Tnh nhn lc lao ng:
Thi gian lm vic ca mt cng nhn
Tlv=Th (Tngh l + Tch nht+Tphp)
Tlv=365 52 9 10 = 294 (ngy).
Trong :
365 : l s ngy trong mt nm.
52 : l s ngy ch nht trong mt nm.
9 : l s ngy cng nhn ngh l.
10 : l s ngy cng nhn ngh php.
H s iu tit cng nhn
365
K= = 1,24
294
6.1.2.3. Nhn lc nh my:
Lao ng theo thi gian hnh chnh:

Bng 6.1
STT Chc v S lng
1 Gim c 1
2 Ph gim c 2
3 Th k gim c 1
4 Phng k thut 4
5 Phng k hoch 3
6 Phng maketing 2
7 Phng k ton ti v 2
8 Phng t chc hnh chnh 2
9 Phng y t 1
10 Nh n 4
11 Cng nhn v sinh 1
12 Li xe 1
Tng cng 24
Lao ng trc tip sn xut:
Bng 6.2

STT Chc nng S ngi/ca S ca S ngi
1 X l tinh bt 2 3 6
2 Chun b mi trng ln men 1 3 3
3 Phn xng ln men 2 3 6
4 Phng nhn ging 2 3 6
5 Phng ha l, vi sinh 5 3 15
6 Lc trong 1 3 3
7 C c chn khng 1 3 3
8 Ty mu 1 3 3
9 Kt tinh 1 3 3
10 Ly tm,p lc 1 3 3
11 S y 1 3 3
12 ng gi 1 3 3
Li xe vn chuyn nguyn liu, 4 3

13 12
sn phm
14 Kho nguyn liu 1 3 3
15 Kho thnh phm 1 3 3
16 Phn xng c in 3 3 9
17 X l ph tr 3 3 9
18 X l nc thi 1 3 3
19 Bo v 1 3 3
20 Tng cng 33 99

Vy s cng nhn trc tip sn xut ca nh my l: Csx = 99 (ngi). T

ta c cng nhn trc tip sn xut m nh my cn c l:
Ncn = K.Csx = 1,2499 = 122,76
Chn 123 ngi.
S ngi lao ng trong 1ca ng nht bng tng s ngi lao ng gin tip
v s ngi lao ng trc tip ca mt ca 24 + 33 = 57 (ngi).
Tng s lao ng trong nh my : 123 + 24 =147 (ngi)
6.2. Tnh xy dng nh my:
6.2.1. Phn xng sn xut chnh.
Trn c s thit b ca nh my v vic thit k mt bng ta c phn xng

sn xut chnh vi cc thng s sau:
Bc ct: khong cch gia hai trc nh v dc nh B = 6 (m), gm 11 bc

ct, chiu di nh: (10 6) = 60 (m).
Bc ct 6 (m), gm 5 bc. chiu rng nh: 4 6 = 24(m).
Din tch nh: 60 24=1440 (m2).
Phn xng sn xut chnh l nh mt tng, tng bao bng gch th dy

220 (mm), nh cao 12,6(m), trn nh c btng ct thp dy 100(mm). Tng
ngn gia cc phng vi nhau c xy bng gch th dy 220(mm), cao 1(m),
phn cn li c ngn cch bng knh trong v khung nhm dy 10(mm).
Kch thc phn xng sn xut chnh: di rng cao = (6024 10,8) m.
Tr nh c lm bng btng ct thp, kch thc (200200)mm, mng

btng M200.
Kt cu mi dng khung thp, chiu cao mi h=2 (m)
Nn nh: chng mn, chng thm, chu c tc ng c hc (ti trng ca thit

b).

6.2.2. Khu cha nguyn vt liu
y l ni d tr tinh bt, lng tinh bt cha trong kho sn xut trong

thi gian 10 ngy .
Tinh bt cha trong cc bao ni lng 2 lp khi lng mi bao l 50kg kch
thc bao 10,403m v c xp chng ln nhau c khong trng thng gi,
mi chng 10 bao. Vy chiu cao mi chng l 10 0,3 =3m.
Khi lng cn sn xut trong 1 ngy:
+ Tinh bt: 17118,081(kg).
Nguyn liu cn cha trong kho:
mtinh bt = 17118,081 10 = 171180,81 (kg).
171180,81
S bao tinh bt l = 3423,6~ 3424 (bao).
50
.N. f
Din tch phn kho cha tinh bt F1 = (m2).
nb
Trong :
N: Tng s bao nguyn liu
f: Din tch chim ch mi bao, f = 0,4 m2.
nb: S bao trong 1 chng.

: H s khong cch gia cc chng, = 1,1.
1,1 3424 0,4

V y F 1 = = 150,6 (m2).
10
150,6 20
Din tch phn i li chim 20% din tch tng = 30,1 (m2).
100
Tng din tch ca kho l : 150,6 + 30,1 = 180,7 (m2).
Kch thc kho : 16126 m.

6.2.3. Kho thnh phm
Chn thng carton c din tch l 0,6 m2 cha cc gi sn phm. Mt

thng carton cha 50 gi.
13535,35
Mt ngy sn xut c =27070,7gi.
0,5
Sn phm d tr trong 7 ngy. Nh vy tng s gi cn cha l:
27070,7 7 =189494,9 (gi).
189494,9
S thng carton l = 3789,89 thng.
50
Cc thng carton c xp trn k tng cch mt t 0,5 mt. Mi k gm 4

tng, mi tng xp 4 hng, mi hng 20 thng.
S thng xp c trn 1 k tng l 804 = 320 thng.
3789,89
S k tng cn l = 11,84. Chn 12 k tng, mi k tng cch nhau
320
1 mt.
Kch thc kho (24187,2) m.
6.2.4 Nh hnh chnh
Gm cc phng sau:
+ Phng gim c : 6 4 = 24 (m2).
+ Phng ph gim c : 2(4 4) = 32 (m2).
+ Phng k ton ti v : 4 4 = 16 (m2).
+ Phng hnh chnh tng hp : 4 4 = 16 (m2).
+ Phng k thut : 6 4 = 24 (m2).
+ Phng maketing : 4 4 = 16 (m2).
+ Phng th k : 3 4 = 12(m2).

+ Phng k hoch : 4 4 = 16 (m2).
+ Phng y t : 3 4 = 12 (m2).
+ Hi trng :
S cng nhn ca ton nh my l 147 ngi, mi ngi chim 1m2.
Sn khu rng 46 = 24 m2. Li i chim 2(201) = 40 m2.
Vy din tch hi trng l 147+ 24+ 40=211 m2
Ta c tng din tch cc phng chim l 399 m2 cha k cu thang, hnh

lang, nh v sinhvv.
Tng din tch cn xy dng ca nh hnh chnh l 504 m2
Xy nh 2 tng, kch thc:
Tng 1: (4264,2) m.
Tng 2: (4264,2) m.
6.2.5 Xng c in
Chn kch thc: ( 12 6 5,4) m.
6.2.6 L hi, kh nn
y l phn xng d xy ra chy n nn c t cui hng gi. Phn

xng c phng bo h lao ng.
Phn xng t l hi c kch thc: (969) m.
6.2.7. Trm bin p
t gc nh my ni t ngi qua li.
Kch thc: (444,8) m.
6.2.8. My pht in d phng
m bo lm vic lin tc nh my c trang b my pht in d phng.

Kch thc: (664,8) m.
6.2.9 Khu x l nc thi
Nc thi trc khi thi ra ng thot nc chung ca khu cng nghip cn

c x l s b. Chn din tch khu x l nc thi l (18x6x4,8) m.
6.2.10 Khu x l nc
X l nc pha ch dch ln men, cho l hi
Kch thc: (1264,8) m.
6.2.11. i nc
Kch thc i nc nh sau:
Chiu cao t i nc: 14 m.
ng knh i nc: 7 m.
i nc l ni cung cp nc cho sn xut v sinh hot.
Lng nc cn cung cp cho sn xut trong 1 h Theo mc7.2: 172,37(m3).
Chn thit k i nc cung cp cho nh my trong mt gi, h s cha y ca

i nc l = 0,85; th tch ca i cha l
172,37
Vthit b= = 202,78 (m3)
0,85
4 202,78
Chn ng knh i nc D = 7m, chiu cao l h = = 5,2 m
3,14 7 2
6.2.12. Nh sinh hot
Nh sinh hot v sinh gm c: phng pht m o v thay mc, phng tm ra,

nh v sinh.
S nhn vin ca ng nht l: 57 ngi.
Khu vc thay : Tnh cho 60% nhn vin ca ng nht l:

57 0,60 = 34,2 (ngi).
Din tch mi phng thay : 0,2 m2/1 cng nhn.
Din tch khu vc thay :
0,2 35= 7(m2).
Khu vc tm:
Tnh cho 60% nhn vin ca ng nht v 6 cng nhn/1 vi tm.
S vi tm:
33
=5,5. Ta chn 6 vi.
6
Kch thc mi phng: (112,5) m.
Nh vy din tch nh tm l 6(11) = 6 m2.
Nh v sinh: s lng nh v sinh tnh bng 1/4 s nh tm.
S nh v sinh:
6
=1,5. Ta chn thit k 2 nh v sinh.
4
Kch thc mi phng: (11,22,5) m.
Din tch nh v sinh l 2(11,2)=2,4 m2.
Tng din tch ca nh tm v nh v sinh l 7+6 + 2,4 = 15,4 (m2).
Kch thc: (644,8) m.
6.2.13. Nh xe my v xe p:
S xe c tnh cho 80% nhn vin ca ng nht.
Mi xe chim 1 m2. Din tch nh xe l 0,8 x 57 x 1= 45,6 m2
Chn nh c kch thc: (963) m.
6.2.14. Gara t:

Nh my c 4 t vn chuyn hng mi xe chim din tch 18 m2 v 1 xe ch

lnh o chim din tch l 8 m2.
Kch thc: (1564,8) m.
6.2.15. Phng bo v:
Xy dng gn cng chnh nh my.
Kch thc: (334,2) m
6.2.16. Nh n:
Tnh cho 2/3 s cng nhn nhn vin trong ca ng nht l :
2
57 = 38 ( ngi)
3
Din tch cho mi ngi l 2,25 m2.
Din tch cn c:
38 2,25 = 85,5 (m2).
Kch thc: (1864,8) m.
6.2.17. Kho nhin liu:
L ni cha nguyn liu ph cho sn sut.
Kch thc: (644,8) m.
6.2.18. Kho ha cht:
L ni t cc thit b h tr cho cng tc phng chy cha chy.
Kch thc: (644,2) m.
6.2.19. Khu t m rng:
Kch thc: (6618) m.
6.3. Qui cch xy dng nh my:
Nh my c 2 cng, xung quanh bao bng hng ro thp.

Trong nh my c trng nhiu cy xanh.
Cc ng i li c nha, chiu rng ca ng l 6 (m).
Khu sn xut v khu hnh chnh c b tr u hng gi. Khu nng lng,
l hi, nh v sinh, khu x l nc thi c b tr cui hng gi m bo tt
yu cu v sinh trnh gy nhim v phng chng chy n tt.
Cc cng trnh khc c b tr hp l thun tin cho sn xut v sinh

hot.
T cc cng trnh xy dng tnh v chn c trn ta c bng tng hp

cc cng trnh xy dng trong nh my nh sau .

Bng 6.3: Tng kt cc cng trnh xy dng trong nh my.
Din
TT Tn cng trnh Kch thc (DRC), m
tch, m2
1 Nh sn xut chnh 6024 10,8 1440
2 Khu nguyn liu 18126 216
3 Kho thnh phm 24 18 7,2 432
4 Nh hnh chnh hi trng 42 6 7,2 252
5 Nh n 18 6 4,8 108
6 Nh xe 964,8 54
7 Gara t 15 6 4,8 90
8 Xng c in 126 5,4 72
9 Trm bin p 444,2 16
10 Nh pht in 664,8 36
11 Nh x l nc 1264,8 72
12 L hi, kh nn 9x6x9 54
13 Nh v sinh 644,8 24
14 i nc DH =75 35
15 Kho nhin liu 6 4 4,8 24
16 Nh bo v (2 nh) 3 3 4,2 18
17 Khu x l nc thi 18x6x4,8 108
18 Nh cu ha 4 x4 x4,8 16
19 Khu t m rng 6618 1188
Tng cng 4255
T bng s liu, ta c tng din tch xy dng nh my l: Fxd = 4255 (m2)

Din tch khu t c tnh theo cng thc:
Fxd
Fk = (m2) [11, trang 44]
K xd
Trong :
- Fk: Din tch khu t xy dng nh my
- Fxd: din tch xy dng nh my, Fxd = 4255 (m2)
- Kxd: Mt xy dng, theo qui nh Kxd = 0,35 0,5. Chn Kxd = 0,35
Thay s vo ta c:
4255 2
Fk = = 12157,14 (m )
0,35
Fsd
H s s dng: K sd =
Fk
Trong :
Fsd = Fxd + Fgt + Fh rnh + Fcy xanh
Vi, Fcx: Din tch trng cy xanh (bng 25% tng din tch cc cng trnh).
Fcx = 0,25 4255 = 1063,75 (m2).
Fgt: Din tch ng giao thng (bng 45% tng din tch cc cng trnh).
Fgt = 0,45 4255 = 1914,75(m2).
Fh rnh = 0,3 Fxd = 0,3 4255= 1276,5(m2)
Fsd = 8510 (m2)
Thay s vo ta c:
8510
K sd = = 0,70
12157 ,14
Vy h s s dng t ca nh my l 0,70

CHNG VII
TNH HI - NC
7.1. Tnh hi.
7.1.1. Tnh nhit cho thit b dch ha tinh bt.
7.1.1.1. Lng nhit un dch tinh bt t 26,50C ln 950C.
Q = G C (t 2 t1 )
Trong :
G: Khi lng dch trong ni dch ha, G = 1856,6(kg).
t2: Nhit cui cng : 95oC.
t1: Nhit ban u ca thit b ly bng nhit mi trng : 26,5oC.
C: Nhit dung ring ca dch tinh bt
C = Chtx + 4186(1 - x) (J/kg).
x: Nng cht ho tan.
713,25
x= = 0,38
1856,6
Cht: Nhit dung ring ca cht ho tan khan.
Cht = 0,607 (kcal/kg.) = 2541,38(J/kg.)
C = 2541,38 0,38+ 4186 (1-0,38) =3561 (J/kg.)
= 0,85 (kcal/kg.).
Q = 1856,6 0,85 (95 26,5) = 108100,5(kcal).
7.1.1.2. Lng nhit gi khi dch 950C trong 40 pht:
Ta c: Q = F T ( tbm - tkk )
Trong , tkk l nhit mi trng, tkk = 26,50C

95 + 26,5
tbm l nhit b mt thit b, tbm = = 60,750C
2
= 9,3 + 0,058 60,75 = 12,8 (W/m2.).
T = 45 60 = 2700 (giy).
F = 5 (m2)
Vy Q = 5 2700 12,8 (60,75 - 26,5)= 5918400(J) = 1413,85 (kcal)
Tng nhit dng cho ni dch ha: Q = 109514,3 (kcal).
7.1.1.3 Chi ph hi cho thit b dch ha:
Q
D =
ihn inn
ihn : Hm nhit ca hi nc nhit hi t.
inn : Hm nhit ca nc ngng.
95oC, ihn = 647,0 (kcal/kg). [12- Tr 312]
inn = 120,3 (kcal/kg).
Lng hi cung cp cho thit b dch ha c tnh:
QM 109514,3
D= = = 207,9(kg).
ih i n 647,0 120,3
D 207,9 60
Cng hi tiu tn: Dh = = = 277,2 (kg/h).
T 45
7.1.2. Tnh nhit cho thit b ng ha tinh bt
7.1.2.1 Lng nhit gi khi dch 620C trong 70 gi:
Ta c: Q = F T ( tbm - tkk )
Trong , tkk : nhit mi trng, tkk = 26,50C.
62 + 26,5
tbm: nhit b mt thit b, tbm = = 44,250C.
2

= 9,3 + 0,058 44,25 = 12,505 (W/m2.)
T = 70 3600 = 252000 (giy)
F = 18(m2)
Vy Q = 18 252000 12,505 (44,25-26,5) =1006827570 (J)
= 240476,6(kcal).
7.1.2.2. Chi ph hi cho thit b ng ha:
Q
D =
ihn inn
120oC, ihn = 647,0 (kcal/kg). [3 ]
Lng hi cung cp cho thit b ng ha c tnh:
QM 240476,6
D= = = 456,57(kg)
ih i n 647,0 120,3
D 456,57
Cng hi tiu tn: Dh = = = 6,5 (kg/h).
T 70
7.1.3. Tnh nhit cho thit b thanh trng dch pha ch

7.1.3.1 Lng nhit un dch tinh bt t 26,50C ln 1250C.
Q = G C (t 2 t1 )
Trong :
G : Khi lng dch a vo thanh trng,
G =3610,3 (kg)
t2: 125oC

t1: Nhit ban u ca thit b ly bng nhit mi trng : 26,5oC
C: Nhit dung ring ca dch pha ch.
C = 4186(1-x) (J/kg.). [6 - Tr 152]
x: Nng cht ho tan
C = 4186(1 0,1) = 3767,4 (J/kg.) = 0,9 (kcal/kg.)
Q = 3610,3 0,9 (125 26,5) = 320056,5 (kcal).
7.1.3.2. Lng nhit gi khi dch pha ch 1250C trong 15 pht:
Ta c: Q = F T2 ( tbm - tkk )
Trong : tkk l nhit mi trng, tkk = 26,50C
125 + 26,5
tbm : nhit b mt thit b, tbm = = 75,750C
2
= 9,3 + 0,058 75,75 = 13,694 (W/m2.)
T2 = 15 60 = 900 (giy)
F = 60 (m2)
Vy Q = 60 900 13,694 (75,75 - 26,5) =36419193 (J) = 8698,5 (kcal).
Tng nhit dng cho thanh trng dch pha ch: Q = 328755 (kcal).
7.1.3.3. Chi ph hi cho thit b thanh trng dch pha ch:
Q
D =
ihn inn
120oC, ihn = 647,0 (kcal/kg). [3]
Lng hi cung cp cho thit b thanh trng c tnh:

QM 328755
D= = = 624,1 (kg).
ih i n 647,0 120,3
D 624,1 60
Cng hi tiu tn: Dh = = = 2496,7(kg/h).
T 15
7.1.4. Cng on c c dch sau ln men
Dch sau ln men c nng 17% s c a qua h thng c c chn

khng khng n qu bo ha to ra dung dch axit glutamic c nng 30%.
Cc i lng th nguyn c lin quan:
DO: Hi sng i vo ni u (kg/h).
Wi: Lng hi th bc ra t cc ni (kg/h).
G: Lng dch lc vo h thng, (kg/h).
Gc: Lng ch phm sau khi c c, (kg/h).
X: Nng cht kh ca dch lc vo h thng chn
Xc: Nng cht kh trong ch phm chn
Khi lng nc bc hi trong qu trnh c c
Xd
W = Gd .(1 ), (kg / h)
Xc
Hay Gd = 3619,8(kg/h).
Thay vo ta c lng hi th bc ra:
17
W = 3619,8 (1 ) = 1568,58 (kg/h).
30
Lng hi t cn cho qu trnh c c:
Trong :
D: Lng hi t cung cp cho qu trnh c c.

W
Ta c: D = , trong :
0,85.n
n: S ni c c n = 1
0,85: H s hiu chnh.
1568,58
Thay s vo: D = = 1845,3 (kg/h).
0,85.1
7.1.5. Sy axit glutamic
t 0, 0 t1, 1 t 2, 2
Calorif
x0, I 0 x1, I1 My sy x 2, I 2
e
m ban u ca axit glutamic: W1 = 3%
m cui cng ca axit glutamic: W2 = 0,4%
Nhit ca khng kh trc khi vo calorife: t0 = 26,50 C
Nhit ca khng kh sau khi ra khi calorife: t1= 800 C
Nhit ca khng kh sau khi ra khi my sy: t2= 400 C
Nhit ban u ca axit glutamic ban u chn bng nhit mi trng
tvl =26,50 C
Nhit ca axit glutamic sau khi sy tR2 = 400 C
7.1.5.1. Tnh ton cc trng thi ca khng kh v vt liu sy
1. Cc thng s trng thi ca khng kh
Trng thi ban u ca khng kh trc khi vo calorife l trng thi ca

khng kh trong iu kin t nhin, ly theo m v nhit trung bnh ca c
nm l :
to = 26,50 C

0 = 82% [ 13 - Tr 99 ]
2. Hm m ca khng kh
0 Pbl
X 0 = 0,622 ,(kg m/kg kk)
P 0 Pbl
nhit to = 26,5oC, p sut hi nc bo ho Pbl = 0,035227 (at),
[ 12 - Tr 316 ]
p sut chung ca kh quyn, P = 1 (at)
0,622 0,82 0,035227

X 0 = 0,622 = 0,0115 (kg m/kg kkk).
1 0,82 0,035227
3. Nhit lng ring ca khng kh m
I 0 = t 0 + (2493 + 1,79t 0 )X 0 (kJ/kg kk)
I 0 = 26,5 + (2493 + 1,79 26,5) 0,0115 = 55,715 (kJ/kg kkk).
4. Hm m ca khng kh sau khi qua calorife
Nhit ca khng kh sau khi qua calorife l 800C.
Hm m ca khng kh : X1 = X0 = 0,0115 ( kg m/kg kkk).
p sut hi nc bo ho t1 = 800C l Pbl = 0,483 (at).
P X1
1 = (%).
pbl ( X 1 + 0,062 )
1 0,0115
1 = = 0,324 (%).
0,483 (0,0115 + 0,062)
5. Nhit lng ca khng kh nng sau khi qua calorife
I 1 = t1 + (2493 + 1,79 t1 )X 1
I 1 = 80 + (2493 + 1,79 80 ) 0,0115 = 110,316 (kJ/kg kkk).

6. Nhit lng khng kh sau khi ra khi my sy
Do ch tnh trong qu trnh sy l thuyt nn I 2 = I1
7. Hm m ca khng kh sau khi ra khi my sy
Chn trng thi khng kh ra khi my sy l t2 = 400C.
I 2 = t 2 + (2493 + 1,79t 21 )X 2
I 2 t2 110,316 40
X2 = = = 0,0274 (kg m/kg kkk).
2493 + 1,79 t 2 2493 + 1,79 40
nhit t2 = 400C, p sut hi bo ho Pb2 = 0,0752 (at).
P X2
2 =
pb 2 ( X 2 + 0,062)
1 0,0274
1 = = 4,076
0,0752(0,0274 + 0,062 ) .
8. Lng khng kh kh vo my sy.
Khi lng acid glutamic m trc khi sy l 587,875(kg/h).
Lng nc bc hi:
G 1 (W1 W2 ) 587,875 (3 0,4)

W= = = 15,747 (kg/h).
100 W1 100 3
Khi lng acid glutamic kh sau khi sy n m 0,4% l:
G2 = G1 W = 587,875 15,747 = 572,128(kg/h).
Lng khng kh kh vo my sy:
G2
L= , (kg/h). [10, trang 165].
X2 X0
572,128
L= = 35982,89 (kg/h).
0,0274 0,0115

9. Nhit dung ring ca acid glutamic
Acid glutamic c cng thc l C5H9NO4.
1
C= n1c1+ n2c2 + n3c3 + .. (J/kg) [12 - Tr 152]
M
Trong : M: Khi lng mol ca hp cht.
ni: S nguyn t ca cc nguyn t trong hp cht.
cj: Nhit dung ring ca cc nguyn t tng ng (J/kg.).
Vy nhit dung ring ca axit glutamic l:
5 7500 + 9 9630 + 1 26000 + 4 16800

C= = 1478,7(J/kg ).
147
10. Cn bng nhit trong qu trnh sy.
Nhit vo:
- Khng kh mang vo: L I 0 , (KJ/h).
- Acid glutamic m vo: G1 C1 t vl , (KJ/h).
- Nhit calorife cung cp: Qc,(KJ/h).
Nhit ra:
- Khng kh m mang li: L I 2 , (kJ/h).
- Acid glutamic kh mang ra: G2 C 2 t R 2 , (kJ/h).
Do tn tht: 0,1 Q2 , (kJ/h).
Gi s C1 = C2 = C = 1478,7 (J/kg.).
Phng trnh cn bng nhit lng:
L I 0 + G1 C1 tV 1 + Qc = L I 2 + G2 C 2 t R 2 + 0,1 Qc

L (I 2 I 0 ) + G2 C 2 t R 2 G1 C1 tV 1
=> Qc =
0,9
35982,89 (110,316 55,715 ) + (572,128 1478,7 40 ) (587,875 1478,7 26,5)

=
0,9
Qc = 12769083 (kJ/h).
Chn hiu sut trao i nhit: = 80 %
Lng nhit thc t cn thit cung cp cho calorife trong mt gi:
Qc 12769083
Qtt = = = 15961354 (kJ/h).
0,8
Lng hi nc bo ho:
Gi d: lng hi nc cn dng trong mt gi, kg
r: n nhit ho hi ca hi nc bo ho 1200C
r = 2207 [12- Tr313]
Qtt = d r , (kJ/h)
Q tt 15961354
d= = = 7232,15 (kg/h).
r 2207
7.1.6. Tnh lng hi cn dng
Lng hi cn cung cp cho nh my trong 1gi:
D = 277,2 + 6,5 + 2496,7+1845,3 + 7232,15 = 11857,85(kg/h).
Lng hi v sinh, tn tht vo cc mc ch khc bng 10% tng lng

hi cung cp cho sn xut.
11857,85 0,1 = 1185,785 (kg/h).
Tng lng hi trong 1 gi l: 11857,85 + 1185,785 = 13043,6 (kg/h).
D
Lng hi thc t cn dng: Dtt =


Vi h s tn tht nhit, mt mt do ng ng cc thit b ph ti, tn tht

do tr lc ng ng v hiu sut l. Chn = 0,75.
13043,6
Dtt = = 17391,5 (kg hi/h)
0,75
7.2. Tnh nc
Nc yu cu phi qua x l m bo ch tiu cht lng trong sn sut.
Gi s 1 kg nc sinh ra 1kg hi. Suy ra, nc dng cho l hi trong 1 gi:

17,39 (m3)=139,12 (m3/ca)
Nc dng cho ha tan tinh bt:
Lng tinh bt sn em ha tan trong 1ca l: 5706(kg).
Lng nc cn dng trong 1 ca l:
28958,47 - 5706 = 23252,44(kg) 23,25 (m3).
Gi s nc cn v sinh thit b: 5 (m3/ca).
Cc qu trnh khc:5 (m3/h).
Tng lng nc cn dng:
139,12 + 23,25 +5 +5 =172,37 (m3/h).

CHNG VIII
KIM TRA SN XUT V NH GI CHT

LNG SN PHM
Kim tra sn xut l vic ht sc quan trng c bit i vi ngnh cng ngh
thc phm. Kim tra sn xut nhm m bo cht lng sn phm ca nh my,
m bo cho cng nhn thao tc ng qui trnh k thut, trnh nh hng xu n
sn phm cng nh nhng s c k thut v h hng ca my mc, thit b. Kim
tra sn xut gip ta nh gi c tnh hnh hot ng ca nh my v ra k
hoch hp l. ng thi, qua pht hin c nhng sai st iu chnh hoc c
bin php ci tin k thut nh my hot ng tt.
8.1. Kim tra u vo ca nguyn liu
Yu cu: tinh bt c mu trng sng ,khng c mu nu hay c v khng c

nm mc pht trin.
8.2. Kim tra cc cng on sn xut
8.2.1. X l nguyn liu
Trong qu trnh thu phn tinh bt cn thng xuyn kim tra nhit , PH, o
mc thy phn ca tinh bt.
8.2.2. Pha ch dch ln men
Cn kim tra t l cht dinh dng cho vo dch trc khi i thanh trng.
8.2.3. Ln men
m bo qu trnh ln men t hiu qu cao phi ch khng ch cc iu

kin k thut sau:
+ Nhit : lun gi 320C.
+ Khi pH gim n 7 phi b sung ur ngay cho pH ln n 8.

+ Khi bt nhiu phi tip du ph bt CO2 thot ra d dng.
+ Thng xuyn o nhit , ng, axit, pH, lng khng kh, p sut.
+ o c trn my so mu.
+ B sung ur.
8.2.4. Cng on tinh ch
+ o nng axit glutamic sau khi c c. Sau khi c c, nng axit

glutamic khong 30%, pH = 5,5 - 6.
+ o pH ca qu trnh kt tinh.
+ Kim tra m ca axit glutamic sau khi li tm, p lc, sy.
8.3. Kim tra cht lng sn phm
Axit glutamic phi m bo cc ch tiu ho l sau:
- Tinh th mu trng sng, cc ht u nhau.
- Phn t lng 147,13
- pH = 3,3.
- m t 0,4 - 0,5 .
- Nhit nng chy l 247 2490 C
- Tan hon ton trong nc, khng tan trong cn, ete v mt s dung mi.

CHNG IX
AN TON LAO NG
Trong nh my, an ton lao ng l vn c t ln hng u. N nh

hng rt ln n qu trnh sn xut, sc kho v tnh mng ca cng nhn cng
nh tnh trng my mc, thit b. Do , cn phi ph bin rng ri cho cn b cng
nhn vin nh my hiu bit v vn dng mt cch c hiu qu.
9.1. Cc nguyn nhn gy tai nn lao ng:
- T chc lao ng v s lin h gia cc b phn khng cht ch.
- Cc thit b bo h lao ng cn thiu hoc khng m bo an ton.
- thc chp hnh k lut ca cng nhn cha cao.
- Vn hnh thit b, my mc khng ng quy trnh k thut.
- Trnh lnh ngh v nm vng v mt k thut ca cng nhn cn yu.
- Cc thit b, my mc c trang b khng tt hoc cha hp l.
9.2. Nhng bin php hn ch tai nn lao ng:
- Ti cc phn xng phi c cc bin bo v quy trnh vn hnh tng loi
thit b.
- B tr lp t thit b ph hp vi qu trnh sn xut. Cc loi thit b c
ng c nh: gu ti, phi c che chn cn thn.
- Cc ng ng hi nhit phi c lp bo n, c p k.
- Phi kim tra li cc b phn ca my trc khi vn hnh xem c h hng
g khng, nu c phi sa cha kp thi.
- Cc thit b cha CO2 lng, kh nn phi t xa ni ng ngi, c p k.
- Kho xng, du, nguyn liu phi t xa ngun nhit. Trong kho phi c
bnh CO2 chng chy v vi nc cha la. Ngn chn ngi v phn s vo
khu vc sn xut v kho tng. Khng c ht thuc l trong kho.

- Ngi cng nhn vn hnh my phi thc hin ng chc nng ca mnh,
phi chu hon ton trch nhim nu my mc b h hng do quy trnh vn hnh ca
mnh.
- K lut ca nh my phi thc hin nghim x l kp thi nhng trng
hp v nguyn tc, lm u.
9.3. Nhng yu cu c th v an ton lao ng:
9.3.1. Chiu sng v m bo nh sng khi lm vic:
- Phi m bo sng ti thiu Emin trong nh sn xut. Nu chiu sng
khng tt s nh hng n sc kho ca cng nhn, khng m bo khi vn hnh
my mc.
- Ban ngy cn phi s dng ngun sng t nhin.
- Ban m s dng ngun nh sng nhn to phi ch tiu v ri.
9.3.2. Thng gi:
Nh sn xut v lm vic phi c thng gi tt.
9.3.3. An ton v in:
* V in chiu sng:
S bng n, v tr treo lp n, cng tc, cu dao phi ph hp vi thao tc.
Cc mch in phi kn, t ni kh ro. Thng xuyn kim tra sng ca bng
n.
* V thit b in:
- Phi c h thng bo ng khi thit b c s c.
- Thit b in phi c rle phng qu ti.
- Cc phn cch in ca thit b in phi m bo bn cht, khng b n
mn.
- Thit b in phi c ni t khi lm vic.
- Khi sa cha thit b in phi cch ly in vi ngi sa cha v c bt th
in.
- Khi ct in phi c bin bo v mang dng c bo him in.
9.3.4. An ton s dng thit b:

- Thit b, my mc phi s dng ng chc nng, ng cng sut.

- Mi loi thit b phi c h s r rng. Sau mi ca lm vic phi c s bn
giao my mc, nu r tnh trng ca sau x l.
- Thng xuyn theo di ch lm vic ca my mc, thit b.
- C ch v sinh, st trng, v du m cho thit b.
9.3.5. Phng chng chy n:
- Nguyn nhn xy ra chy n l do tip xc vi la, do tc ng ca tia la
in, do cn nc trong l hi, cc ng hi b co gin, cong li gy n.
- phng chy n cn phi tun theo cc thao tc v thit b c hng
dn.
- Khng ht thuc ti kho nguyn liu, xng du, gara t
- Phi nc, thit b cha chy.
- Thng xuyn kim tra nh k cng tc phng chy ti nh my.
9.3.6. An ton vi ho cht:
Cc ho cht phi t ng ni quy nh. Khi s dng phi tun theo quy nh
ra trnh gy c hi, n mn v h hng thit b.
9.3.7. Chng st:
m bo an ton cho cc cng trnh trong nh my, phi c ct thu li cho
nhng cng trnh v tr cao.

KT LUN
Nh s gip tn tnh ca c gio hng dn Trng Th Minh Hnh v cc

thy c khc trong b mn cng nh gia nh, bn b, em hon thnh n tt
nghip vi ti: Thit k nh my sn xut axit glutamic t tinh bt sn, nng
sut 4570 tn sn phm/nm.
Vic thit k nh my sn xut axit glutamic tinh th p ng mt phn no
cho cc nh my sn m chnh, dc phm v mt s ngnh khc, gp phn thc
y nn kinh t ca t nc ni chung v khu vc min trung ni ring , tn dng
c ngun nguyn liu c sn trong nc. Qua qu trnh thit k, ti c c hi
p dng v kim tra li nhng kin thc tip nhn c sut 5 nm qua v c th
hiu su hn v cng ngh sn xut axitglutamic.
Mc d ti c nhiu c gng trong cng vic, nhng vi thi gian c hn
cng vi nhng hn ch v kin thc chuyn mn v kinh nghim thc tin ca bn
thn nn sai st l iu khng th trnh khi. Ti rt mong nhn c nhng kin
ng gp chn thnh ca thy c v bn b nng cao kin thc, kinh nghim
nhm phc v cng tc sau ny.
Nng, ngy 25 thng 5 nm 2011.
Sinh vin thc hin

TI LIU THAM KHO
Ting vit
1. Hong Kim Anh, Ng K Xng, Nguyn Xch Lin (2004), Tinh Bt Sn V

Cc Sn Phm T Tinh Bt Sn, NXB Khoa Hc V K Thut, Tp H Ch
Minh.
2. Ti liu t cng ty Ajinomoto.
3. GS, TSKH Nguyn Bin, PGS.TS Vn i, TS.Nguyn Trng Khung,
TS.Trn Xoa, S tay qu trnh v thit b cng ngh ha cht v thc phm
(1992), Tp 1, NXB i hc v k thut H Ni.
4. TS.Trng Th Minh Hnh (2004), Bi ging cng ngh sn xut axt amin,
HBK Nng.
5. PGS.TS. Nguyn Th Hin (2004), Cng ngh sn xut m chnh v cc sn
phm ln men c truyn, NXB Khoa Hc v K Thut, H Ni.
6. L Vn Hong (2004), Cc qu trnh v thit b cng ngh sinh hc trong
cng nghip, NXB Khoa Hc v K Thut.
7. ThS. Trn Xun Ngch, ThS. Phan Bch Ngc, Bi ging mn hc cng ngh
ln men, HBK Nng.
8. PGS.TS. Lng c Phm (2004), Cng ngh vi sinh vt, NXB Nng
Nghip.
9. Trn Vn Ph, L Quang Dng(1991), K thut sy nng sn, NXB Khoa
hc v k thut H Ni.
10. Trn Vn Ph, Tnh ton v thit k h thng sy, NXB Gio dc
11. Trn Th Truyn (2006), C s thit k nh my, Khoa Ha HBK Nng.
12. Trn Xoa, Nguyn Trng Khung, Phm Xun Ton (1992), S tay qu trnh
v thit b cng ngh ha cht v thc phm Tp 1, NXB i hc v k thut
H Ni.

13. Trn Xoa, Nguyn Trng Khung, Phm Xun Ton (1992), S tay qu trnh
v thit b cng ngh ha cht v thc phm Tp 2, NXB i hc v k thut
H Ni.
Ting Nga
14. ...(1997),
.
Web
15. http://ebg.vn/chi-tiet-san-pham/6656/tinh-bot-san (ngay 15-2)
16. http://vi.wikipedia.org/wiki/Qu%E1%BA%A3ng_Nam (ngay 15-2)
17. http://cyanua1201.violet.vn/entry/show/entry_id/395243 (ngay 15-2)
18. http://www.3dchem.com/molecules.asp?ID=52, (ngay 15-2)
19. http://voer.edu.vn/content/m32464/1.1/ (ngay 30-2)
20. http://forum.hanoifishing.com/showthread.php?t=10779 (ngay 30-2)
21. http://www.semvn.net/sem/modules.php?name=News&op=viewst&sid=410,
(ngay 30-2)
22. http://www.vatgia.com/raovat/3905/2463440/thiet-bi-trao-doi-nhiet-thiet-bi-
trao-doi-nhiet-dang-tam-tam-trao-doi-nhiet.html (ngay 3-3)
23. http://www.traderscity.com/board/products-1/offers-to-sell-and-export-1/beer-
equipment-mash-tank-29148/ (ngay 3-3)
24. http://www.simerics.com/gallery_mixer.html (ngay 8-3)
25. http://www.vocw.edu.vn/content/m10510/latest/, cp nht 8/3
26. http://www.chinapharmachinery.ru/e8-preparation-vessel.html (ngay 25-4)
27. http://www.3dchem.com/molecules.asp?ID=52, truy cp 27/4
28. http://changshuyaoji.en.alibaba.com/product/200908537-
200055190/Fermentor_Fermenter_.html (ngay 30-4)
29. http://www.processequipments.net/chemical-plant-crystallizers.html (ngay 30-
4)
30. http://www.heinkelusa.com/heinkel-centrifuge-equipment/pennwalt-super-
decanter (ngy 30-4)

31. http://www.topmachinebiz.com/product/95406/Decanter-Centrifuge.htm (ngy

30-4)
32. http://www.princeton-indiana.com/wastewater/pages/biosolids/press.htmld
(ngy30-4)
33. http://ttmindustry.vn/default.asp?prod=3 (ngy30-4)
34. http://www.quangnam.gov.vn/web/quangnam/danhchonhadautu/khucongnghi
ep/kcndiennam-dienngoc? (ngy 30-4)
35. http://www.scielo.br), truy cp 30-4

Sản Xuất Acid Glutamic 25850L 1 Ngày

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Sản Xuất Acid Glutamic 25850L 1 Ngày

Uploaded by

Copyright:

Available Formats

n tt nghip 0 GVHD: PGS.TS.

Trng Th Minh Hnh

TI: Thit k nh my sn xut

GVHD: PGS.TS. Trng Th Minh Hnh

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

cp cho th trng rng ln v tin n xut khu. Vi nhng u im nh vy nn

Thit k nh my sn xut axit glutamic

Lng hi t cung cp cho cc phn xng ly t l hi ring ca nh my.

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

Hnh 2.1 Tinh bt sn [17] Cht ho tan : 0,1 1,3%

2.2. M chnh v axit glutamic

2.2.1 Tnh cht vt l [6]

Thit k nh my sn xut axit glutamic

Bt ngt (cn gi l m chnh) l mui mononatri ca axit glutamic hay nari

Axit L (+) - glutamic (thng gi axit glutamic) l nhng tinh th khng

Hnh 2.2 Cu trc phn t axit glutamic[18]

Thit k nh my sn xut axit glutamic

phn ng vi amoniac cho aminoaxit mi l glutamin. Trong y hc, axit glutamic

2.3. Phng php sn xut axit glutamic:

C nhiu phng php sn xut axit glutamic, t cc ngun nguyn liu

+ Phng php ho hc. [5, trang13]

Phng php ny ng dng cc phn ng tng hp ha hc tng hp nn

+ Phng php thu phn. [5, trang 13]

Phng php ny s dng cc tc nhn l ha cht hoc enzyme thy

-u im: + Khng ch c qui trnh v cc iu kin sn xut.

+ C th p dng cc c s th cng, bn c gii ha.

+ n nh c cht lng sn phm ca tng m.

+ Nguyn liu s dng phi c hm lng protein cao

+ S dng nhiu thit b, ha cht, thit b chng n mn

+ Hiu sut thp dn n gi thnh cao.

+ Phng php kt hp [5, trang 15]

Thit k nh my sn xut axit glutamic

y l phng php kt hp gia ha hc v ln men.Vi phng php ny

+ Phng php ln men (sinh tng hp) [5, trang 14]

Ln men l phng php c s dng rng ri sn xut axit glutamic.

Phng php ny dng cc chng vi sinh vt c kh nng tng hp ra axit

+ Nguyn liu r hn so vi hai phng php trn.

+ t s dng ho cht, thit b chng n mn.

+ Hiu sut qu trnh rt cao, gi thnh h.

+ C th s dng cc loi nguyn liu khc nhau .

+ To ra axit glutamic dng L, c hot tnh sinh hc cao.

+ Qu trnh i hi yu cu k thut cao v nghim ngt.

Sn xut axit glutamic bng phng php ln men ngi ta s dng 2

2.4.Chng vi sinh [20]

Thit k nh my sn xut axit glutamic

t 1956, c kh nng ln men t tinh bt, ng, khoai, khoai m to ra axit

Ging vi khun thun khit ny c ly t ng thch nghing ti cc c s

Chng vi khun ging phi c kh

* C ch tng hp tha axit glutamic:

Tnh thm ca mng t bo b thay i v thiu biotin, do tc dng ca

Thit k nh my sn xut axit glutamic

2.5.Nhng yu t nh hng n qu trnh ln men [7]

Thit k nh my sn xut axit glutamic

to ra alanin v axit lactic. V vy, ngi ta phi b sung thm penicilin km hm

Thit k nh my sn xut axit glutamic

Thit k nh my sn xut axit glutamic

Ln men Chun b men ging

B sinh khi t bo Lc tch sinh khi

Ty mu Than hot tnh