Hx consistent with ischemia = most important Metoprolol (25 mg BID) ACS = Hx of chest pain + EKG substernal pain on exertion EKG 15-30 min/episode Nitroglycerin MC risk factor: HTN dull, squeezing, pressure ACE-inhibitor Acute Coronary exercise stress test: intermediate risk w/ normal EKG; worst risk factor: DM S3/S4 Statin Syndrome looks for reversible ischemia; (also smoking, hyperlipidemia, & family Hx rales Morphine catheterize abnormal results 1st degree relative (<55 male, <65 female)) (normal exam does not exclude ACS) echo: evaluate wall & valve motion, & EF; Ca++-channel blockers used for normal wall motion excludes MI catheterization/angiography symptomatic relief only, not mortality telemetry LMW heparin (SC enoxaparin) EKG: ST depression clopidogrel/prasugrel/ticagrelor chewable ASA (2 x 81 mg) Troponin I: rises 3-4 hr after pain onset, stays positive no O2 unless hypoxic NTG 1-2 wks dont wait for troponin or CK-MB results NSTEMI chest pain statin (LDL goal: <100 mg/dL) CK-MB: rises 2-4 hr after onset stays positive 1-2 days -blocker (metoprolol) (best test of reinfarction); false+ with CHF & renal statins can cause increased LFTs & myositis ACE-I failure morphine Myoglobin: rises at 1-4 hr cath/angio despite medical intervention angioplasty/cath or thrombolytics for PCI no O2 unless hypoxic clopidogrel/prasugrel/ticagrelor EKG: ST elevation eptifibitide or abciximab (glycoprotein chest pain (DO NOT use heparin) CXR IIb/IIIa inhibitor) used if PCI & stent rales chewable ASA STEMI Echo S3 NTG Troponin I: elevated Takotsubo cardiomyopathy due to JVD statin (LDL goal: <100 mg/dL) BUN: elevated overwhelming emotions; mimics anterior -blocker (metoprolol) wall STEMI ACE-I angiography when >70% stenosis 1-2 vessel: medical Rx & possible PCI EKG: repeat if symptoms change ASA +/- clopidogrel/prasugrel/ticargrel 3 vessel w/ LV dysFx or left main: bypass Echo (DO NOT use heparin) CAD/angina stress test: 80-85% of max HR to assess ST depression -blocker (metoprolol) ASA only in chronic stable angina on EKG; stress test+ = reversible perfusion defect statin (LDL goal: <100 mg/dL) Ranolazine: Na+-channel blocker for ACE-I (if EF <35%) refractory angina cases only LBBB stress test w/ dipyridamole or dobutamine echo EKG (excludes ischemia & arrhythmia) O2 & elevate head MCC: I AM in high salty fluid sudden onset dyspnea, CXR (excludes effusion, cardiomegaly, Furosemide (Lasix) IV 20 mg, double every relieved by sitting up congestion/vascular fluid overload) 20-30 min till urine produced Ischemia +/-rales, ABG monitor I/O Arrhythmia Acute Pulmonary +/- peripheral edema BNP NTG paste, IV, or SL Medication (most common) Edema (CHF) S3, JVD Troponin/CK-MB morphine 2-4 mg IV Infection tachycardia BUN/Cr: elevated >20:1 (pre-renal azotemia) hemodialysis for refractory cases HTN crisis diaphoresis, nausea CBC: hyponatremia transfer to ICU if systolic < 90 mmHg Salty food echo: determine EF, syst/diast dysFx, valve fx (DO NOT use -blockers in acutely ill pt) Fluid overload (iatrogenic) Systolic DysFx ACE-I (or ARB if cough; or alternative is AICD if low EF despite medical therapy CHF hydralazine/nitrate if hyperkalemia) (lowers mortality) -blocker (metoprolol, carvedilol) spironolactone for stage III/IV CHF only ACE-I not beneficial in diastolic dysFx (eplerenone as alternative) diuretics & digoxin (no mortality benefit) biventricular pacemaker if QRS >120 ms chest pain, dyspnea/CHF, IV anti-hypertensives: labetalol, enalaprilat, Hypertensive HTN crisis = severe HTN with end-organ blurry vision, confusion, or nitroprusside (stroke caution: do not lower crisis damage renal insufficiency BP > 25% 1st few hrs)
SOB worsens on exertion, systolic dysFx: diated cardio.
-blocker, ACE-I, spironolactone, diuretics improves with rest CXR: congestion or pulmonary vascular redistribution diastolic dysFx: hypertrophic card. Cardiomyopathy (for dilated cardiomyopathy) rales echo (alternative MUGA or left heart cath) restrictive card: sarcoidosis, amyloidosis, treat underlying cause (for restrictive card.) +/- peripheral edema hemochr., cancer, endomyocardial fibrosis syncope, LOC systolic murmur at LLSB: valsalva & standing EF is preserved Hypertrophic chest pain (increases); squatting & leg raise (decreases) -blocker (metoprolol) Obstruction S4 gallop echo implantable defibrillator (for syncope) diuretics, ACE-I, dehydration, & digoxin will Cardiomyopathy sudden death in athletes left heart catheterization worsen HOCM NO anticoagulation if present < 48 hr anticoagulate if risk for stroke (CHAD2) hemodynamic instability = chest pain, SOB, EKG (if normal, Holter as outpatient, telemetry for cardiomyopathy confusion, hypotension (<90 mmHg systolic) inpatient) HTN CHAD2 = 0/1: ASA &/or clopidogrel Arrhythmia palpitations exclude thyroid disease, alcohol, caffeine CHAD2 = 2+: warfarin, rivaroxaban, or age >75 dabigatran (no INR monitoring required, not DM reversible) prior Stroke/TIA (anticoagulate) rate control <100 bpm within 30 min causes: HTN (MC), CHF, alcohol, cocaine, EKG: irregularly irregular rhythm, P-waves absent, metoprolol (5 mg IV every 5 min 3x, then thyroid disease, rheumatic fever normal QRS oral 50 mg bid, max 200 bid), OR (immigrants), dilated atrium palpitations, +/- chest pain A-fib/A-flutter (do not measure HR by radial pulse) diltiazem (0.25 mg/kg, then IV 0.35 mg/kg, lightheadedness echo (detects valve disease & clots) then oral 30 mg qid, max 200 qid) other rate control meds: verapamil, esmolo, Troponin/CK-MB use digoxin if BP is low or borderline propranolol, atenolol (digoxin doesnt lower BP; slow acting) Cardioversion: a-fib rhythm control EKG: narrow QRS tachycardia (>160bpm), P-waves telemetry absent MCC by abnormal AV conduction vagal sudden onset palpitations adenosine SVT no physical findings maneuvers: carotid massage or valsalva SOB, lightheadedness b-blocker (metoprolol or diltiazem) echo to exclude other pathology cardioversion if hemodynamically unstable troponin/CK-MB are not useful procainamide, amiodarone, flecainide, or previous EKG Wolf-Parkinson palpitations, EKG: small/short P-R, delta waves (early ventricular sotalol digoxin & Ca++-ch blocker use worsens White Syndrome lightheadedness, syncope depolarization), SVT alternating w/ v-tach electrophysiology (EP) to identify abnormal symptoms or arrhythmia conduction tract for ablation Multifocal Atrial a/w COPD 3 P-wave morphologies & normal QRS same as for a-fib/a-flutter NO -blocker (worsens COPD) Tachycardia saline bolus if systolic <90 mmHg EKG: wide QRS, reproducibly regular, sustained VT MCC is previous MI (ischemia), also low check K+. Mg++, Ca++, O2 EXTREME EMERGENCY >30 sec Mg++, Ca++, or O2, high/low K+, cocaine V-Tach synchronized cardioversion if unstable chest pain, confusion, SOB Troponin/CK-MB toxicity, low EF dilated cardiomyopathy amiodarone, lidocaine, procainamide, & echo Torsade de Pointes Mg++ if stable GIVE CPR! recent MI CPR defib CPR epi CPR defib after 2 min unsynchronized cardioversion V-fib treat V-tach without pulse the same loss of pulse CPR - amiodarone epinephrine or vasopressin if no response amiodarone (lidocaine alternative) Bradycardia low systolic < 90 mmHg EKG: determine hemodynamic stability if unstable/symptomatic if stable/asymptomatic lightheadedness ventricular pacemakers give wide QRS & abnormal T- atropine (0.5-1.0 mg IV; 3 mg max) Sinus brady, 1st degree AV block, or Mobitz I = no treatment confusion, syncope, SOB waves transcutaneous pacemaker Mobitz II or 3rd degree AV block = pacemaker Sick Sinus pacemaker if slow (>3 sec pause) aka tachy-brady syndrome Syndrome b-blocker if fast sudden LOC = cardiac or exclude cardiac & neurologic causes neurologic cause EKG MI gradual LOC: metabolic Troponin/CK-MB ventricular arrhythmia vasovagal episode echo Syncope sudden recovery of telemetry aortic stenosis measure O2, glucose, Na+, Ca++ consciousness: cardiac HOCM MRI for brainstem causes gradual recovery: seizures, head CT & echo w/o murmur findings are useless seizure glucose, O2, drug O/D brainstem stroke increased venous return (squatting or legs raised) increases all murmur intensities dyspnea (except MVP & HOCM) CHF Valvular Heart echo (best initial assessment) decreased venous return (sudden standing or edema endocarditis PPx if valve was replaced Disease catheterization (most accurate test) valsalva) decreases left-sided murmur murmurs (except MVP) congenital/rheumatic fever handgrip increases afterload; worsens regurgitations, improves HOCM echo (best test) ACE-I/ARBs decreased afterload EKG: AR will show LVH (SV1 + RV5 >35 mm) due to any cause of dilated cardiomyopathy no ABX PPx before dental procedures unless Aortic/Mitral CXR: enlarged LA & LV louder with squatting & leg raised dyspnea, rales, edema valve was replaced Regurgitation softer with valsalva & standing AR: diastolic decrescendo murmur @ LLSB surgery: AR EF <50% or LVESD >55mm, worsens with hand grip ( afterload) MR: pansystolic @ axilla that radiates MR EF <60% or LVESD >45mm angina a/w CAD no treatment if asymptomatic echo (best test) Aortic Stenosis syncope surgical replacement if symptomatic DO NOT use ACE-I or ARB (worsens) stress test & angiography (due to CAD) CHF (worse prognosis) balloon valvulopasty if pt too ill EKG: biphasic P-waves in V1 & V2 diuretics (fluid overload) young immigrant MS can cause LA enlargement & a-fib w/ CXR: double bubble, L mainstem bronchus pushing digoxin or -blocker (HR control) Mitral Stenosis a-fib, dysphagia, hoarseness, pressure on esophagus & recurrent laryngeal up, straightened L heart border balloon valvuloplasty (or alternative: valve early onset stroke nerve. TEE & L heart cathetherization is best test replacement) palpitations echo (best test) -blocker for palpitations & chest pain Mitral Valve improves with squatting & leg raised atypical chest pain mid-systolic click w/ late systolic murmur no treatment if asymptomatic Prolapse worsens with valsalva & standing incidental finding EKG & CXR will be normal no endocarditis PPx chest pain: relieved by treat underlying cause friction rub on auscultation sitting up, worse on NSAIDS (ibuprofen & naproxen) Pericarditis EKG: ST elevation in all leads except AVR, MCC: viral infection inspiration add colchicine to reduce recurrence risk PR segment depression alternative is prednisone for symptoms also fever, recent lung infection pulsus paradoxus (>10 mmHg with inspiration) fluids prevent/reverse tamponade renal failure SOB, lightheadedness CXR: enlarged heart shadow thoracocentesis chest wall trauma Pericardial dyspnea, hypotension, JVD CT: pericardial effusion pericardial window placement SLE, RA, Wegners Tamponade tachycardia echo: effusion pressing on right heart: RA & RV cardiac catheterization: pressure equalization recent MI, cancer of chest organs sudden loss of pulse diastolic collapse is the first sign of all chambers in diastole EKG: low voltage, QRS electrical alternans Constrictive edema, JVD, Kussmauls S3 pericardial knock surgical removal is best Pericarditis sign CXR: fibrosis, thickening, calcification diuretics & salt restriction prevents build-up enlarged liver & spleen Chest CT/MRI shows more detail ascities STOP SMOKING! angina of the calves ankle/brachial index (ABI): ankle pressure >10% ASA (or clopidogrel) Hx of tobacco smoking Peripheral Artery pain in legs relieved by rest lower than brachial (ABI <0.9) = obstruction Cilostazol Hx of HTN, DM, hyperlipidemia Disease decreased peripheral pulses lower extremity Doppler ACE-I for BP pain with exertion, spinal stenosis worse smooth, shiny skin (severe) angiography Statin (LDL goal: <100 mg/dL) walking downhill, but not uphill tight glucose control in diabetics Abdominal Aortic AAA >5.0 cm = surgical repair USS: all men age >65 who have ever smoked Aneurysm AAA <5.0 cm = USS in 6 months CXR: wide mediastinum b-blocker (labetalol) decreases pulse pressure Thoracic Aortic chest pain radiates to the CT angiogram, MRA, TEE (90-95% sensit/specif) nitroprusside Aneurysm back angiogram with catheter is most accurate surgical repair Heart Disease & peripartum cardiomyopathy Eisenmengers leads to pulmonary HTN Mitral stenosis Pregnancy w/ LV dysFx (blood volume increases by 50% in pregnancy) Aortic stenosis pleuritic chest pain that CXR changes with respiration oximeter Pneumonia ABX prophylaxis dyspnea, fever, cough, ABG sputum sputum culture sudden onset pleuritic chest Pulmonary CT pulmonary angiogram pain Embolus CXR, oximeter, ABG recent surgery Aortic dissection chest pain radiates to back CXR: wide mediastinum CT angiogram, MRA, TEE Costochndrtis chest tender on palpation none GERD epigastric pain, burning improves with antacids position feet up/head down Hypotension systolic < 90 mmHg repeat BP manually Tx first, Dx later. IVF 250-500 mL NS bolus over 15-30 min BUN: Cr ratio >15-20:1 Dehydration low urine Na+ (<20) high urine Osm (>500) CBC: leukocytosis Sepsis Fever Blood cultures BP normalizes lying flat Orthostasis Tilt-table test Premature Ventricular EKG: alternating normal QRS with wide, premature incidental finding no specific treatment Contractions PVCs (PVCs) atropine for symptoms 30 heart block recent MI EKG: bradycardia, canon A waves pacemaker for all pt EKG: inferior wall MI RV infarct recent MI right-sided EKG: V4 STEMI recent MI, new murmur Valve Rupture balloon pump in some pt rales/congestion recent MI, new murmur Septal Rupture balloon pump in some pt increased O2 sat in RV