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    11 views27 pages

    CMMP (169) B

    Uploaded by

    Charles Britto
    mol

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
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    of 27
    72 Rogistration No. ‘QUESTION PAPER nae Contre of Exam, B Name of candidat ‘Signature of tnvigiiator ENTRANCE EXAMINATION, 2016 Pre-Ph.D./Ph.D. in MOLECULAR MEDICINE [eld of study Code : cMmP (165) } Time Allowed : 3 hours Maximum Marks : 70 INSTRUCTIONS FOR CANDIDATES Candidates must read carefully the following instructions before attempting the Question Paper li) Write your Name and Registration Number in the space provided for the purpose on the top of this Question Paper and in the Answer Sheet. (i) Please darken. the appropriate Circle of Question Paper Series Code on the Answer Sheet. (ii) The Question Paper is divided into two Parts : Part—A and Part—B. Both Parts have multiple-choice ‘questions. All answers are to be entered in the Answer Sheet provided with the Question Paper for the purpose by darkening the correct choice, i.c., (a) or (b) or (c} or (a) with BALLPOINT PEN only against each question in the corresponding Circle. (iv) Part—A consists of 30 questions and all are compulsory, () Part— contains 60 questions. Anawer any 40 questions {n case any candidate answers more than the required 40 questions, the first 40 questions attempted will be evaluated, (vi) Bach correct answer carries 1 mark. There will be negative marking and ¥ mark will be deducted for e each wrong answer. (wi) Answer written by the candidates inside the Question Paper will not be evaluated, (vill) Calculators and Log Tables may be used. (ix) Pages at the end have been provided for Rough Work. (} Retum the Question Paper and Answer Sheet to the Invigilator at the end of the Entrance Examination. DO NOT FOLD THE ANSWER SHEET. INSTRUCTIONS FOR MARKING ANSWERS 1. Use only Biue/Black Ballpoint Pen (do not use pencil) to darken the appropriate Circle, 2 Please darken the whole Circe, 3, Darken ONLY ONE CIRCLE for each question as shown in example below : Wrong Wrong | Wrong Wrong | Correct OHO FOOOFOOG|OOO8|OOHOCO 4. Once marked, no change in the answer is allowed. 5. Please do not make any stray marke on the Answer Sheet. 6. Please do not do any rough work on the Answer Sheet. 7. Markyour answer only in the appropriate space against the nuraber corresponding to the question. 8. Ensure that you have darkened the appropriate Circle of Question Paper Series Code on the Answer Sheet. /72-B PART—A Answer all questions What will be the absorbance at 500 nm of a 1x 10“ M solution of a compound whose molar absorption coefficient is 5000 liters/mol/cm if a 1 cm cell is used? fa os () O41 } 5 @ 10 A A piece of paper in the shape of a triangle has an area of 42 cm?. If the height of the triangle is 7 cm, the base of the triangle should be (a) 120m ‘ (b) 10 om (c) 8 cm (@) 6 cm 3. Cyclooxygenase-1 and 2 are responsible for the (b) synthesis of leukotrienes from arachidonate {e) conversion of ATP to cAMP | (a) synthesis of prostaglandins from arachidonate {@) metabolic degradation of cAMP | 4. Recently, there has been excitement in scientific community and media due to the ‘ detection of ‘gravitational waves’ using LIGO (Laser Interferometer Gravitational Wave Observatory). Who predicted the existence of gravitational waves? | fal Stephen Hawking (b) Albert Einstein (c) Galileo Galilei (a) C. V. Raman 172-B 3 [P.7.0. 5. The Indian National Flag was designed by Pingali Venkayya, an Indian freedom fighter. How many lines are there in Ashoka Chakra as depicted on the National Flag of the Republic of India? fa) 18 lines {b) 20 tines (24 tines (@ 26 tines, 6. 0° is isoelectronic with (a) zn (b) Mg?* fe) kK" (a) Ni?* 7. Imereased OH” ion concentration leads to (a) increased rate of Sy2 and Sy! reaction (b) increased rate of Sy1 and no effect on Sy,2 reaction (©) increased rate of Sy2 and no effect on Sy 1 reaction {d) decreased rate of Sy2 and no effect on Sy reaction /72-B 4 10. 1. /72-B ‘Two bus tickets from city A to Band three tickets from city A to C cost € 7 but three tickets from city A to Band two tickets from city A to Ccost ® 73, What are the fares for cities B and C from A? fa) © 4 and 23 (o) © 13 and © 17 (9) © 1S and F 14 {@) 17 and € 13 Laadli counted in the following way on the fingers of her left hand She started by calling the thumb 1, the index finger 2, middle finger 3, ring finger 4, little finger 5 and then in reversed direction calling the ring finger 6, middle finger 7 and 80 on. She counted up to 1994, She ended counting on which finger? (@) Thumb (b) Index finger () Middle finger (@) Ring finger Computerized axial tomography (CAT) scan is a (a) X-ray imaging technology {b) nuclear magnetic resonance (NMR) imaging technology () computer-aided design (CAD) technology (a) All of the above If acetic acid is mixed with sodium acetate, then H* concentration will (a) be increased (b) be decreased (c) remain same (a) Any of the above depending on the pH +8 [P-T.0. 12. 13. 14, 18. (72-B Which of the following is not an element? (a) Graphite (&) Diamond ()_ Rhombic sulphur (@) 22-carat gold Which one of the following undergoes reaction with 50% sodium hydroxide solution to give the corresponding alcohol and acid? (a) Phenol () Benzaldehyde () Butanal (@) Benzoie acid Catalyst SnCl,/HCI is used in (a) Cannizzaro’s reaction (b) Clemmensen reduction {e)_ Stephen's reduction (4) Rosenmund's reduction Ina reaction °?Beggq to 88 Y,,g, the number ofa and B-particles emitted respectively are (a) 4and4 (b) 6 and 4 () 4and8 (a) 4 and 2 16. 47. 18. 19. /72.B Who was the first scientist credited with pointing out that certain gases could cause a greenhouse effect? (@) John Tyndall (b) Charles Darwin (c) Roger Tory Peterson (a) Stephen Jay Gould ‘The study of how people use tools to perform work, and how they physically relate to working environment is called (a) engineering (b) ergonomics {c) agronomy (a) physiology If wavelength and amplitude of a wave are denoted as A and A respectively, then the shortest horizontal distance between any crest and trough is equal to fl 50th fb) A L dora @ A The formation of thrombus in heart can lead to (a) angina (b) heart attack (©) cardiac arrhythmia [d) None of the above 7 [P.T.0. 20. 21. 22, /72-B In a.class, there are 15 girls and 10 boys. Three students are selected at random. The probability of 2 girls and 1 boy being selected is fa) 21/46 (b) 25/117 () 1/50 (a) 3/25 { ‘Two mirrors are placed at right angle to each other. Ifa man could stand between them to comb his hair, then how many images he will observe? (@ 2 (bo) 3 @ 1 (4) None With the increase of temperature, the surface tension of the liquid (a) may increase or decrease depending on the density of the liquid (b) remains the same (c) always increases (a) always decreases ao 23, 24. 2s. 26. (72-B A hollow iron pipe is 21 cm long and its external diameter is 8 em. If the thickness of the pipe is 1 cm and iron weighs 8 g/cm®, the weight of the pipe is fa) 36 kg (b) 3-696 kg {c) 36-235 kg (@) 36919 kg Five farmers have 7, 9, 11, 13 and 14 apple trees respectively in their orchards. Last year, each of them discovered that every tree in their own orchard bore exactly the same number of apples. Further, if the third farmer gives one apple to the first, and the fifth gives three to each of the second and the fourth, they would all have exactly the same number of apples, What were the yields per tree in the orchards of the third and fourth farmers? fa) it and9 (b) 7 and 9 () Mand 7 (@) it and 13 Which number in the following series is the odd one out? 2, 5, 10, 17, 26, 37, 50, 64, ...? (a) 26 (b) 17 () 64 (a) 37 60 + 5x 12/(180/3) =? fa) 13 (b) 120 (©) 60 @ 61 9 [P.T.0. 28. 29, 30. 172-B ‘A small jar contains 4 red balls and 3 green balls. Another jar contains 2 red balls and 3 green balis. Ifyou randomly select any of the two jars and take out a ball, what will be the probability that the ball taken out is red? (@) 57-14% () 54-29% {e) 48:57% (a) 41-43% A student needs to weigh 10 g of pure CaCl, (MW = 111 g/mol} to make a solution but he discovers that the lab has the hexahydrated form (CaC! -6H,0; MW = 219'1 g/mol} only. How much of CaCl, -6H,0 should the student weigh? fa) 102¢ e) 141g ( 174g @) 197% An 8 ml solution of glucose with a concentration of 0-25 mol L“! is kept in a bottle. A student adds 492 mL of water to it. What will be the concentration of the jinal solution? {@) 0-025 mol L*! (>) 0-004 mol L*? {0125 mol L*? (4) 0-063 mol L“* Ram invested F 1000 in a bank at an annual compound interest of 10% for 2 years. After 2 years, he again invested the whole amount at an annual simple interest of 12% for 5 years, What will be the final total value of his investment (in ®)? (a) 1760 (b) 1776 (1926 (@) 1936 10 fe 32. 34, PART—B Answer any forty questions ‘The structure of the products A and B formed in the following reaction scheme respectively are or PhoP=CHz, ,_HBI/tg02, 9, “or ace Br » eae : iC) CY and : “ra Which of the following has pentagonal planar shape? (a) XerZ (0) PCy () XeoR, (@) SbF, In Fe(CO),, which d-orbital participates in dsp? hybridization? s P fa) dy ) dp © day @) ay Which of the following is showing the correct increasing order of required energy for electronic transitions? @) nant name> n+ror> a0 () nam nont Amos > NPgg > Pagy > °>Ugy the reaction order is fa) Ba, 0,8 (db) BB, a, o (c] o, Bo, B (@) 2,0, 6,8 ‘The most prevalent mechanism by which gram-negative bacilli acquire chloramphenicol resistance is {a) decreased permeability into the bacterial cell, {b) acquisition of a plasmid encoded for chloramphenicol acetyl transferase (c) lowered affinity of the bacterial ribosome for chloramphenicol (4) switching over from ribosomal to mitochondrial protein synthesis An enhancer sequence is (a) always present upstream to the promoter (b) present upstream or downstream of transcription factor binding regions (c)_ expedite DNA polymerase capture (a) downstream of transcription factor binding regions Ascorbic acid acts as vitamin C in (a) guinea pig (b) mouse () rat (@) None of the above 12 89, Sexual mode of reproduction in Protozoa is known as {)_ plasmogamy {b) plasmotomy (©) anisogamy {d) _schizogony 40. In acid rain, SO, accounts for : (@) 70% {b) 100% , {ce} 50% (@) 30% 41. Bacterial biofilms are (a) bacteria that are grown on plastic film in biotechnology industry {b) sessile forms of bacteria {e) specific polymeric films produced by bacteria (a) None of the above 42. Approximate mass of a polypeptide of 400 amino acid residues is fa) 11 kilodaltons () 44 Kilodaltons : (0) 22 kilodattons (d)_ 88 kilodattons 43. Covalent linking of which tag targets a protein for degradation? (a) Antibody () Epoeitin {Ubiquitin (@) Biotin /72-B 13 . [P.T.O. 47. 172-B Which one of the following performs the antigen-presenting role to trigger T-cell immune response? (a) T-cell receptors () Immunoglobulins (] Complement (4) MHC class | and II proteins A form of binding motif containing a nearly identical sequence of 60 amino acids in many eukaryotes is {a} homeodomain motif {o) zinc finger motif {c)_ leucine zipper motif (@) universal motif When tryptophan is present in the environment of E.coli, the tryptophan binds to the (@) tp operon (&) trp promoter () trp polymerase (@) tp repressor Which of the following does not match correctly? (a) Exon splicing—occurs in nucleus () Post-translational modifications—phosphorylation (6) snRNA—splice out exons from transcript (4) Activated enhancers—trigger transcription 14 48. 51. (72B Gelfiltration chromatography using porous beads packed in a column, separates proteins on the basis of (a) size and shape {b) charge to mass ratio ()_ shape of the protein (4) None of the above A purified protein sample contains 10 yg of protein and has an enzyme activity of 1 m mol of ATP synthesized/sec (1 unit). What is the specific activity of the final purified sample? (@) 1,000 units/mg (©) 10,000 units/mg {€} 100,000 units/mg (@) 1,000,000 units/mg DNA fingerprinting depends on differences in length of which of the following classes of DNA? (a) Multispecies DNA (b) Pseudogenes {c)_ Simple sequence DNA {4) Small muitigene families Mammals possess brown fat beneath the skin which helps to fa) increase heat loss {b) insulate the body {c)_ produce metabolic heat {d) store water 15 {P.T.0. 52. 53. 54, 55. 172.B Blocking of an enzyme activity by a substrate analog is called (@) allosteric inhibition (b) feedback inhibition (3) competitive inhibition (2) non-competitive inhibition ‘The fungal mycelium penetrates the root cells by means of projections known as (a) arbuscules (b) absorbing organ () haustoria (4) None of the above ‘The hormone reducing transpiration rate by inducing stomatal closure is (a) ABA (b) ethylene () cytokinin (@ auxin ‘The photorespiration is related to (a) chloroplast (b) mitochondria (©) peroxisome (a) glyoxysomes 16 56, The role of APS in SDS PAGE is to (a) act as a catalyst in the polymerization of acrylamide (b) act as a source of free radicals {c)_ act as a bridge between acrylamide and bis-acrylamide s (@) act as a pore builder in the polymerized gel 57. ABO blood group antigens in human are differentiated from each other on the basis of (@) sialic acid (b) lipids (€) spectrin (2) glycoproteins 88. Which one of the following relations holds true for the specific growth rate (i) of a microorganism in the death phase? f@ peo (be) H<0 (2) 0<#

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