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Differential Diagnosis

1.1 Differential Diagnosis


1. Nasal Polyps
Nasal polyps are abnormal lesions that originate from any portion of the
nasal mucosa or paranasal sinuses. Polyps are an end result of varying disease
processes in the nasal cavities. Most commonly polyps are benign
semitransparent nasal lesions that arise from the mucosa of the nasal cavity or
from one or more of the paranasal sinuses, often at the outflow tract of the
sinuses19.
2. Adenoid cystic Carcinoma
Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that
most commonly develops in the salivary glands or other regions of the head
and neck. In some cases, ACC may arise in other primary sites, such as the
skin; the breast; the neck of the uterus (cervix) in females, the prostate gland
in males; or other areas20.
3. Nasopharyngeal Non-Hodgkin Lymphoma
Non-Hodgkin lymphomas (NHLs) are tumors originating from lymphoid
tissues, mainly of lymph nodes. Nasopharyngeal Non-Hodgkin Lymphoma.
occur in nasopharungeal location. These tumors may result from
chromosomal translocations, infections, environmental factors,
immunodeficiency states, and chronic inflammation21.
4. Sinonasal Lymphoma
Lymphoma of the nasal cavity and paranasal sinuses is extremely rare,
may mimic benign processes, and may manifest either in an isolated fashion
or in conjunction with systemic disease. B-cell lymphomas22.
References

1. Lind H, Joergensen G, Lange B, Svendstrup F, Kjeldsen AD. Efficacy of ESS


in chronic rhinosinusitis with and without nasal polyposis: a Danish cohort
study. Eur Arch Otorhinolaryngol. 2016 Apr. 273 (4):911-9.
2. Budakoglu, B., Altundag, K., Aksoy, S., Kaplan, M.A., Ozdemir, N.Y., Berk,
V., Ozkan, M., Algin, E., Kandemir, N., Dogu, G.G., Harputluoglu, H.,
Arslan, U.Y., Coskun, U., Isikdogan, A., Oksuzoglu, B. Outcome of 561 non-
metastatic triple negative breast cancer patients: multi-center experience from
Turkey. J. BUON. 2014;19:872878.
3. Donin N, Filson C, Drakaki A, Tan HJ, Castillo A, Kwan L, et al. Risk of
second primary malignancies among cancer survivors in the United States,
1992 through 2008. Cancer. 2016 Jul 5.
4. Peng KA1, Kita AE, Suh JD, Bhuta SM, Wang MB.Sinonasal lymphoma:
case series and review of the literature.Int Forum Allergy Rhinol. 2014
Aug;4(8):670-4. doi: 10.1002/alr.21337. Epub 2014 Apr 23.
5.

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