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We evaluated the effects of H.

pylori antigens using in vitro two cellular


models of gastric epithelial cells and fibroblasts, which had been
independently exposed to H. pylori components.

In this study, we showed different effects of subunit A of urease,


cytotoxin associated gene A protein, lipopolysaccharide (LPS) as well as
compounds included in a glycine acid extract on the regenerative activity
of gastric epithelial cells and fibroblasts. Our results indicate deleterious,
dose dependent influence of H. pylori LPS on this process.

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