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ท่างู บทท - 2
ท่างู บทท - 2
2.1 (Dysmenorrhea)
2.1.1
2.1.2
2.1.3
2.1.4
2.1.5
2.1.6
2.1.7
2.1.7.1
2.1.7.2
2.1.7.3
2.1.7.4
2.2 (Symptom Self-Management)
2.3
9
2.1 (Dysmenorrhea)
2.1.1
( , 2544)
( , 2548)
( , 2548)
( , 2549)
( , 2551)
2.1.2
(Proctor & Faquhar, 2004; Jamieson & Steege, 1996)
48.4 84.2 17 (Burnett MA.,et al,
2005) 48.4 (Mario IO.,et al, 2009) 61.27 (Sule & Ukwenya, 2007)
64.3 (Osuga Y, 2005) 68.7 (Chan SC, 2009) 69.4 (Lee LK,
2006) 72 (Desalegn TZ, 2009) 89.5 (Saadutu TT, 2007)
84.2 (Tongchai K, 2004)
10
10 21.1
(Sharma P, 2008; Cakir
M, 2007; Lee LK, 2006; Tongchai K, 2004)
(Saadatu & Josephine, 2007)
(Sharma P, 2008; Cakir M, 2007)
21.1 63.6
1.8 (Tongchai K, 2004)
(Burnett
MA, 2005) (Patel V, 2006)
2.1.3
2 (primary
dysmenorrhea) (secondary dysmenorrhea)
6
12 (menarche) (menarche)
40
20 2 20
3 20 4 6 2
spasmodic dysmenorrhea (lower abdomen)
(low back) (inner thighs)
congestive dysmenorrhea (dull aching)
(premenstrual
syndrome; PMS) (lethargy) (depression)
(irritability) (nausea) (vomiting)
(headache) (syncope) (Kulig JW, 1990; Chesney & Tasto,
1975)
1 2 48 72 12
11
3
18 24
endometriosis, adenomyosis, pelvic congestion pelvic adhesion
(cervical stenosis)
(gynecologic malignancy)
endometriosis
24
(Johnson N, 2006)
2.1.4
(infertility) (endometriosis)
(chronic pain syndrome)
(Johnson N, 2006)
(emotional/psychological problems)
(anxiety) (emotional instability)
(imitation of patients mothers negative feelings about menstruation)
29.6
6
(faulty outlook on sex) (Ylikorkala & Dawood, 1978; Jeffcoate N, 1975;
12
(earlier age at menarche)
(long menstrual periods) (heavy menstrual flow)
(smoking)
(Proctor & Farquhar, 2004) (obesity)
(Parazzin F.,et al, 1994)
(Golomb LM., et al, 1988 cited in LattheP, 2006)
(Mergler & Vezina N, 1985 cited in LattheP, 2006)
(adrenergic)
(menopause) (Sundell
G.,et al, 1990)
2.1.5
2.1.5.1 Prostaglandin F2 alpha (PGF2alpha)
F2 alpha (PGF2alpha)
(PG) (phospholipids)
2 ( phospholipase A2) (arachidonic
acid) (cyclooxygenase) 2
(PGF2alpha)
(PG) 2 (PGF2 alpha)
(secretory)
13
(proliferative) PG
(secretory) (PG)
( proliferative)
(PG) (PG)
(secretory) (proliferative) 3
2 (PGF2alpha) 2
(PG) 2 (PGF2alpha
PGE2) (myometrium)
(ischemia)
(PG)
(PG)
(Eden JA, 1998; Dawood MY, 1990)
(Secondary dysmenorrhea)
(Smith RP, 1993)
2.1.6
2.1.6.1
-
(sexual abuse)
(Jamieson & Steege, 1997)
14
2.1.6.2
(Rapkin AJ, 1998)
(prolapsed submucous myoma)
2.1.6.3
(laparoscopy)
(laparoscopy)
(endometriosis) (pelvic adhesion)
(Husby GK.,et al, 2003)
15
2.1.7
2.1.7.1 (Traditionally established drug treatment)
(analgesic)
paracetamol, aspirin paracetamol-opiate
(Proctor & Faquahar CM, 2004) PGF2alpha (prostaglandin synthetase inhibitors)
(Non-steroidal anti-inflammatory drugs: NSAIDs)
cyclo-oxygenase PG
80
(Dawood & Khan-Dawood, 2007)
NSAIDs
48
PG PG
PG
NSAIDs
NSAIDs (FDA)
diclofenac, ibuprofen, ketoprofen, meclofenamate, mefenamic acid naproxen
aspirin paracetamol (Zhang & Li Wan
Po, 1998)
16
NSAIDs 30 - 60
NSAIDs
indomethacin cyclooxygenase-2 inhibitors (COX-2)
rofecoxib 25 mg valdecoxib 40 mg
naproxen
NSAIDs
(Morrison BW.,et al, 1999)
2.1.7.2
(combined oral contraceptive pill; combined OCP)
(ovulation)
PG late luteal phase
(atrophic)
90 (Silem M,
2003; Vercellin P.,et al, 2003)
(FDA)
2.1.7.3
laparoscopic uterine nerve ablation presacral neurectomy (Rapkin AJ, 1998)
17
2.1.7.5 (nutrition)
(
, 2549)
3 (niacin)
90
3 2 2 - 3 3
(flushing) (Hudgin AP, 1954 cited in Dennely CE, 2006)
RCT
1 (vitamin B1)
(Magnesium) (Fish oil) (vitamin E)
1 (vitamin B1)
556 ( 12 21 )
spasmodic dysmenorrheal 1
90 1
(Gokhale LB, 1996)
(Magnesium)
21 50 3
(Proctor & Murphy, 2001)
(Fish oil) - 3 (omega 3 fatty acids)
-6 (,
) -3 (, canola oil wheat germ)
-6 PGF2alpha, thromboxane A2
leukotriene B4 -3 eicosapentanoic acid docosahexanoic acid
PGE3, thromboxane A3 leukotriene B5
-3
(Saldeen & Saldeen, 2004) 42
(fish oil)
(placebo) (Proctor & Murphy, 2001) -3
19
(antiplatelet)
(anticoagulants)
(supplements) (Dennehy CE, 2006)
(vitamin E)
PG chidonic acid (Ziaei S.,et al, 2005)
100 278 150 IU 500 IU 2-3
(Zeaei S.,et al, 2005;
Ziaei S.,et al, 2001; Blanche Butter & McKnight, 1955 Dennely CE, 2006)
(antiplatelet proporties)
(anticoagulants)
400 IU 400 IU
(Dennely CE, 2006)
(Herbal)
saffron, celery seed anise (SCA)
3 3
3 SCA mefenamic
acid (NSAIDs) (placebo) (Nahid K.,et al, 2009)
20
(Tsen Y-F.,et
al, 2005)
2.1.7.6 (total body modification)
(nervous system dysfunction)
(Hitchcock ME, 1976)
(Kokjohn K.,et al, 1992; Rosette P, 2004;
, 2552)
2
()
21
2 - 3 3
2 ()
2
1
: http://www.nursing.siam.edu/data1/Gmail/skeletal51.doc
2.1.7.7 (acupressure)
(Cho & Hwang, 2009)
3 2-3
1
22
: http://www.guashathai.com/image/mypic_article/Untitled-3.jpg
2.1.7.8 (acupuncture)
4,000
(Witt CM.,et al, 2008; Maciocia and Kaptchuk, 1998 Jun E-J.,et al, 2007)
2.1.7.9 (transcutaneous electrical nerve
stimulation; TENS)
( Milsom I., et al, 1994; Dawood & Ramos, 1990) 42 60
NSAIDs
23
(2552)
2.1.7.10
40
(, 2549)
1
3 4 20 40
24
(analgesic) paracetamol, aspirin, paracetamol-opiate
PGF2alpha (prostaglandin synthetase inhibitors)
(Non-steroidal anti-inflammatory drugs: NSAIDs) diclofenac, ibuprofen, naproxen
(combined oral
contraceptive pill; combined OCP) PG late luteal phase
(TENS)
2.3
17 (Burnett MA., et al, 2005) 48.4 (Mario IO., et al,
2009) 61.27 (Sule & Ukwenya, 2007) 64.3 (Osuga Y, 2005)
68.7 (Chan SC, 2009) 69.4 (Lee LK, 2006) 72 (Desalegn TZ,
2009) 89.5 (Saadatu TT, 2007) 2004 84.2
(Tongchai K, 2004) 2008 84.9 ( , 2008)
(Eryilmaz & Ozemir, 2009; Zegeye., et al, 2009; S.
Ohde., et al, 2008; French, 2005; David., et al, 2004)
2 10
(Self management behavior)
(
, 2549)
28
( , 2549)