CHEM 230 ORGANIC CHEMISTRY LAB 1

Fall 2017
Instructor Basit Yameen
Room No. 9-429
Office Hours Tuesday and Wednesday 2:30 4:30 pm
Email basit.yameen@lums.edu.pk
Telephone 35608481
Secretary / TA Saba Kanwal, Hafiz Syed Usama Bin Farrukh
TA Office Hours Tuesday Friday 2:00 4:00 pm ( Ext. 3767)
Course URL (if any) N/A

Course Basics
Credit Hours 2
Lecture(s) No. of Lecture(s) Per Week 1 Duration
Recitation / Lab (per week) No. of Lecture(s) Per Week 1 Duration 4 hours
Tutorial (per week) No. of Lecture(s) Per Week N/A Duration N/A

Course Distribution
Core Biology & Chemistry majors

Elective Yes
Open for Student Category SBASSE Students
Close for Student Category N/A

COURSE DESCRIPTION
This introductory lab course is designed to familiarize students to the basic skills and techniques used in organic
chemistry. These techniques include separation, purification and identification of organic compounds based on
crystallization, chromatographic separation/purification, solvent extraction, fractional distillation for
separation/purification, and spectroscopic techniques such as UV/Vis and IR spectroscopy for identification.
Students will also perform simple one-step as well as multistep synthesis of drugs or dye molecules and
characterize them using various tools. Students will experience practical demonstration of most of the organic
chemistry concepts learnt in CHEM 231 Fundamentals of Organic Chemistry.
COURSE LEARNING OBJECTIVES
CLO 1 Separate a mixture of solvents using fractional distillation
CLO 2 Isolate and purify the components of a mixture of organic compounds in
aqueous/organic media
CLO 3 Extract natural products using steam distillation
CLO 4 Synthesize simple organic compounds such as artificial flavoring agent, para-red dye and
aspirin
CLO 5 Synthesize relatively complex organic compounds/drugs using multiple steps.
COURSE Anti-PREREQUISITE(S)

COURSE PREREQUISITE(S)
CHEM 231: Fundamentals of Organic Chemistry

UNDERGRADUATE PROGRAM LEARNING GOALS & OBJECTIVES

PLO 1 To familiarize students with the standard techniques for the isolation of organic
compounds.
PLO 2 Equip students with synthesis and purification skills.
PLO 2 Practical experience on the characterization of organic compounds using UV-visible and
IR spectroscopic techniques.

Grading Breakup and Policy

Safety practices in the lab: 15 %
Prelab Quiz(s): 15 % (8-10 Quizzes)
Lab Reports: 25 %
Lab Performance: 30 %
Viva Voce: 15 %
Instructor has the privilege to change the grading scheme which, if
availed, will be conveyed to the students well in time.

Examination Detail
Yes / No: No

Midterm Combine / Separate:

Exam Duration:
Exam Specifications:
Yes / No: No
Combine / Separate:
Final Exam
Duration:
Exam Specifications:
COURSE OVERVIEW
Lab Recommended Objectives /
Topics
experiments Readings Application
Week 1 Introduction to ChemDraw Provided To learn to draw structural formulae of simple
manual and complex organic compounds
Week 2 Purification of organic Provided To learn to purify organic compounds by selective
compounds by re- manual precipitation and filtration
crystallization
Week 3 Separation of a mixture of Provided To learn to separate a mixture of organic solvents
acetone and toluene manual of different boiling points
Week 4 Isolation of antioxidant Provided To learn to isolate organic compounds from
compounds from tomatoes manual natural resources using column chromatography
Week 5 Extraction of piperine from Provided To learn to isolate organic compounds from
black pepper (Piper nigrum) manual natural resources using column chromatography
Week 6 Extraction of natural Provided To learn to isolate natural products from natural
products by steam manual resources using steam distillation
distillation
Week 7 Synthesis of artificial Provided To learn to synthesize, purify and characterize
flavoring agent manual simple organic compounds
Week 8 Synthesis of para-red Dye Provided To learn to synthesize, purify and characterize
manual simple organic compounds
Week 9 Synthesis of Aspirin An Provided To learn to synthesize, purify and characterize
analgesic, antipyretic and manual simple organic acompounds
anti-inflammatory drug
Week 10-13 Multistep synthesis of Provided To learn to synthesize, purify and characterize
anticonvulsant drug manual simple organic compounds/drugs using multi-
step synthesis

Textbook(s) / Supplementary Readings

Textbook:
Vogels Text Book of Practical Organic Chemistry, By Brian S. Furniss, Antony J. Hannaford,
Peter W. G. Smith and Austin R. Tatchell.
Others recommended readings: Various web links given in the Lab manual at the end of each experiment