BILBERRY

BILBERRY
Standardized and refined dry extract of Vaccinium myrtillus fruits
(EP: between 32.4 % and 39.6 % anthocyanins; USP: NLT 36 % anthocyanins).

Linnea extract is obtained exclusively from the fruits of shrubs, native to the wilds of Northern and Eastern
European Countries, which are recognized to have the most effective active substance composition.
The European Bilberry is rich in Flavonoids. Anthocyanins are the main flavonoids in Bilberry and they have
shown to be potent antioxidant compounds, up-regulating the defenses against oxidative stress.

Bilberry has been widely used as a remedy for poor vision and “night blindness”. Taken orally, it improves
visual acuity in healthy individuals and may be useful to individuals with eye diseases such as cataracts,
macular degeneration, retinitis pigmentosa, glaucoma and myopia. It is indicated as adjuvants in the
preventive treatment of diabetic retinopathy.
Bilberry Extract preparations are used in the prevention and as adjuvants in the treatment of vascular and
blood disorders such as varicose veins and increased capillary permeability.

The Vaccinium berries

from European woods
Linnea extract is obtained exclusively from the fruits
of shrubs, native to the wilds of Northern and Eastern
European Countries, which are recognized to have the
most effective active substance composition.
Fruits are widely harvested and checked carefully prior
to shipment. Bilberries are soft and juicy and thus highly
susceptible to damage.
In order to check that the quality of the fruits is
maintained from harvest to delivery, Linnea staff is
present on site to monitor all procedures involved
in harvesting, cleaning, refrigerating, storing and
transporting them.
TECHNICAL DESCRIPTION
Name of the plant Vaccinium myrtillus L.
Part of the plant used Berries
Description Fresh Bilberry Fruit Dry Extract, Refined and Standardised
CAS number 84082-34-8
Appearance Dark-violet, amorphous and hygroscopic powder
Solubility Insoluble in acetone and chloroform, partially soluble in water
Storage Preserve in tight container, protected from light, heat and humidity.

STRUCTURAL FORMULA
R

R1 Cyanidin 3-O-glycose R2=H, R=R1=OH

CI-
Delphinidin 3-O-glycose R=R1=R2=OH
Malvidin 3-O-glycose R1=OH, R=R2=OMe
HO 0+
R2 Peonidin 3-O-glycoside R=OMe, R1=OH; R2=H
Petunidin 3-O-glycoside R=R1=OH; R2= OMe
R3= arabinose or glucose or galactose
O–R3

OH

Fresh Bilberry Fruit Dry Extract, Bilberry Ethanol Extract

Refined and Standardised*
Identification of Anthocyanins: TLC Complies Complies
Identification of Anthocyanins: HPLC Complies Complies
Content of Anthocyanins: HPLC Between 32.4 % and 39.6 % NLT 36.0%
(on dry basis, expressed as Cyanidin
3-O-glucoside chloride)
Content of Anthocyanidins: HPLC NMT 1.0 % NMT 1.0%
Heavy metals NMT 20 ppm NMT 20 ppm
Water Content NMT 4.5% (LoD) NMT 4.5% (KF)
Ash NMT 2.0% (Total Ash) NMT 3.0% (Sulphated Ash)
Heavy Metals NMT 20 ppm NMT 20 ppm
Microbiology 2.6.12 Ph Eur, current edition 2.6.12 Ph Eur, current edition
*Complies with the Eur. Ph. monograph: “Fresh Bilberry Fruit Dry Extract Refined and Standardised”, current edition

The product is free from GMO, allergen, gluten, lactose and from any animal compound.
The Raw material, intermediates and auxiliary compounds are free from pesticides, dioxin and aflatoxins.
About Linnea
Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of Botanical Extracts
and Active Pharmaceutical Ingredients of Natural Origin in Bulk form.
Linnea Ingredients are suitable for the use in the Pharmaceutical, Health-Food and Cosmetic Industries.
The company employs a team of experienced professionals specialized in the extraction
and purification of plant materials and in the synthesis of fine chemicals.

Best solutions, everywhere

Linnea’s service is tailored to the needs of its customers.
With our extensive knowledge of international requirements and dispatch procedures, prompt efficient
delivery is guaranteed just about anywhere in the world.
Thanks to the company’s competence and reliability, Linnea exports its products to more than 60
countries across 5 continents and supplies more than 200 clients per year.

Headquarters US office
Linnea SA Linnea Inc.
Via Cantonale 435 McCartney Street Easton,
CH-6595 Riazzino (TI) PA 18042
Switzerland USA
Tel: +41 (0)91 850 5050 Tel: 888-253-0044 (US) or +1 610-253-7950
Fax: +41 (0)91 850 5070 Fax: +1 610-253-7970
info@linnea.ch dstanek@linnea.ch
www.linnea.ch www.linnea-us.com