1136 Journal of Medical Education the doctor at an earlier stage and although this inereases the technical difficulties of diagnosis it also increases the effectiveness of treatment. It is the author’s hope that this book will help bridge the gap between hospital and general practice and prepare the student for the altered emphasis and different clinieal material. The purpose is to describe how a family doctor works and thinks. Signs and Symptoms. Applied Pathologic Physiology and Clinical Interpretation. Edited by Cyan Mircueut MaeBryoe with 81 contributors, 4th Ed. Philadelphia and Montreal: J. B. Lippincott Company, 1960. 921 pp. $14.00. ‘The chief aim in the treatment of every subject in this book is the development of understanding and insight into the dis- turbed mechanisms resulting in abnormal clinical evidence. An attempt is made to synthesize and integrate the available rel- evant information, from sources often frac- tionated and scattered, so as to make it meaningful and useful in the explanation of how and why certain signs and symptoms develop. Much of the material in this edi- tion has been completely rewritten and all has been thoroughly revised. Ten new con- tributors to this edition bring fresh insight and add much wide-ranging information gleaned from their special fields. Principles of Biochemistry. ApRaHAM Wars, Pump Hanptzr and Ew L. SMirH. 34 Bd. New York: McGraw-Hill Book Company, 1964. 993 pp. $16.50. The objective of this book continues to be the presentation of the material in a manner to be encompassed by 2 student in a single course in biochemistry, while at the same time providing him with a reference book useful in later years of medical or graduate school. The edition has had an almost complete rewrite, To extend the ranges of the readers, especially grad- uate students, citation is made of many valuable reviews, monographs, and special- ized treatises in each subject. In this edi- tion changes in the arrangement of material were made, both in chapter headings and in the location of certain subjects. Vow. 89, DECEMBER, 1964 Taxonomic Biochemistry and Serology. Edited by CHartes A. Leone with 66 contributors. New York: The Ronald Press Company, 1964. 704 pp. $16.50. This book contains 47 papers that were presented at the International Conference on Taxonomic Biochemistry, Physiology, and Serology, University of Kansas, Sep- tember 4 to 6, 1962, The arrangement of papers is in natural groupings by kinds of organisms or in concession to the principal experimental method involved. Value judg- ments of the data or their interpretation have not been made. Animal and Clinical Pharmacologic Tech- niques in Drug Evaluation. Edited by Joun H. Nopiwe and Peter EB, SIEGLER with 92 contributors. Chicago: The Year Book Medical Publishers, Inc., 1964. 639 pp. $18.00. It is the aim of this book to present in abbreviated form a discussion of the var- ious techniques available as well as 2 clinical appraisal of their relative useful- ness in both animal and human studies. The book is an assembly of the material used in a course in clinical pharmacology offered at Hahnemann Medical College and Hospital. The course is offered over a ‘two-year training period for those having completed a two-year general medical resi dency. us Diseases of Children. Savt Kruc- ‘MAN and Ropert Warp. 84 Ed. St. Louis: ‘The C. V. Mosby Company, 1964. 403 pp. $15.75. ‘The purpose of this book continues to be to provide a concise and handy descrip- tion of certain common infectious diseases of children, It is written primarily for pediatricians, general practitioners, and medical students who deal with children. It is not meant to be an all inclusi text on infectious diseases, and certain notable exceptions are clearly pointed out by the authors. In this rapidly moving field, with the development of new vaccines and other immunizing agents, together with ication of causative organisms, much of this edition has had to be rewritten.