CENTROESCOLARUNI

VERSI
TY-SCHOOLOFMEDI
CINE

YearLev
el1
I
NTEGRATI
NGLEARNI NGACTIVI
TY#2
Apri
l25-May22,2017

CASE:

A55y ear
-ol
dfemaleschoolteacherconsul
tedatanout
-pat
ientcli
nicwi
thswel
l
ingand
di
schargeonherr
ightbigtoe,sustai
nedaft
erhavi
ngapedicureinaparl
or.

5yearspri
ort
oconsult
,shewasdiagnosedwit
hDiabet
esMell
it
us.Shehasbeennon-
compli
antwit
hhermedicat
ionofMetformi
n500mgoncedaily.Sheexper
iences
fr
equencyofuri
nat
ionandonandoffloosebowel
mov ement
.

Laborat
ory:
CBC:Hemogl obi
nlevel
of10.1gm/dl
;
Fast
ingbloodsugar:El
evat
edat7.
9mmol
/l
,
Uri
naly
sis:(
+2)albumin

Cl
i
nical
Impr
essi
on: DM Ty
pe2,
wit
hcompl
i
cat
ions

Gui
deQuest
ions:

1.Discusst hemechani smsofi nsuli

nsecr eti
on,i
tssignaltransducti
onandphysiol
ogic
effects
2.Expl ai
nther egulator
ymechani smsi nvolv
edinthemai ntenanceofnormalbl
ood
gl
ucose
3.Discusst heef f
ectsofi nsuli
ndeficiency,oncarbohydrate,fatandprot
einmetabol
ism,
i
ncl udealsot henon-hy poglycemicef f
ects
4.Discusst hedi f
ferentpathophysiologicdefect
sassoci atedwi t
htype2Diabet
es
5.Discusst hemechani smsl eadi
ngt ot hedif
fer
entsignsandsy mptomsand
compl icati
onsment i
onedi nthecase.
6.Dr
awaconceptmap.