Statement of Research Interest
Che Dieudonne Tabong
Research Area and Current Interest
I am broadly interested in structural characterisation and elucidation of
molecular structures in science with a special interest in X- ray crystallography.
Specifically, my future research interest is shaped by the fact that in scientific
research today, Elucidation of molecular structure is necessary to identify or
confirm the structural identity of a chemical compound during chemical research
or product development. Unknown substances or impurities can be difficult to
identify. Chemical structural elucidation of new and novel compounds is necessary
to support compound regulatory submissions for a number of scientific and
industrial sectors such as agrichemicals, pharmaceutical and new chemical entity
registrations.
Current and Past Research
In my past research work during my PhD program, working as part of group,
the synthesis, characterisation and applications of coordination compounds,
particularly of Nitrogen and Oxygen donor ligands with the first and second row
transition metals was of major interest. The synthesis methods general included,
hydrothermal synthesis, sol-gel and calcination to yield products, as well as
evaluation of the biological and magnetic
tivities of the synthesized complexes.
During the work, although major characterisation techniques such as Infrared and
UV/Visible spectroscopy, Thermogravimetric analyses, X-ray diffraction studies
and microscopic techniques were used, x-ray crystallography was of utmost
importance in the confirmation of the proposed and resulting structures.As such, understanding and better characterising chemical entities through
x-ray crystallography is probably the most important technique to determine the
structure of any molecule; from small molecules to large supramolecular
assemblies as well as assemblies biological macromolecules at atomic resolution
since the x-rays are electromagenetic radiation with wavelengths in range of the
same dimensions of the distance of atoms in molecules. As such, the position of
every atom in the molecule is determined within a relatively small range of
uncertainty. With a successful elucidation of an actual structure for a given
compound, the results have implications in a wide variety of fields related to the
functions of the studied molecule such as material science, drug design,
mineralogy, molecular dynamics, catalysis and many more.
Future Research Aspirations
In this regar’ds, more hands on x-crystallography, ranging from sample
preparation, mounting, recording and extraction of data, computation and
interpretation of data and registration of data in public database systems such as
Cambridge crystallographic Database Centre will help me to be better off in the
development of my country and the word at in interdisciplinary research ranging
from Organic chemistry, material science, inorganic chemistry material science,
physical chemistry and even computational chemistry