Magnitude of responseiniacton —p> O72 34567 6 OD Days aftr vil infection Tanate immunity ‘Adaptive immunity “ype; MO ee : arto, Protection #, | oo Ye | maine Ete ry infection ve eet sab * pole Eracaon IMC bok wget! CDE waecad nag ot | Inocion | oe ced | oa teat — Woverent > Shedding Sites of repletion ween ‘Surte @ ui ou > foo 1 repaint marae fesse a ome se gees. ®HFd Muscle Liver Sploon Blood vossele & SON Pena ee (secondary viremia) 41L\™N 122 Brain 9 2° replication Lie ¢ Skin® Salivary glands © Rabies |{ Arena |[ Polio Mumps || Harta || West Nile Kidney © Vacs zoster Mousepox ‘Incubation period Time TABLE 179-2. Sequence of Measles Virus Infection in Uncomplicated Primary Disease ‘ine in dropet nasa or large droplet in const with he epithet surtoce of {he nasopharynx or poss the conjunctiva. lntection of epee and virus muietion Extension of infection to regional mphold tissue Primary virmia Secondary viremia ‘organs ial content in organs opi dminishes.gure 238-2 pk spas ne urd mes ug ey trash fom ‘te er Osa arse Peet ote Nh nage ying 2500 Inet Rep ee gop