Chapter IV

RESULTS AND DISCUSSION

This chapter presents the results and the interpretations of the various qualitative laboratory
tests and the statistical treatment of data.

A total of 430 strains representing diverse gram-positive and gram-negative bacterial species
were examined for susceptibility to fosfomycin utilizing the Bauer-Kirby agar disk diffusion and
the Steers’ agar dilution methods. Tentative criteria are proposed for the interpreta various
labotion of the diameters of resultant inhibition zones (50 μg fosfomycin disks plus 50 μg
glucose-6-phosphate) on Mueller-Hinton agar, based on MIC breakpoints of d 16 μg/ml =
sensitive (S), 32–64 μg/ml = intermediate susceptible (I), and ≥ 128 μg/ml = resistant (R). For
staphylococci: ≥ 20 mm = S; 14–19 mm = I; ≤ 13 mm = R;
for Enterobacteriaceae and Pseudomonas aeruginosa: ≥ 16 mm = S; 11-15 mm = I; ≤ 10mm =
R.

© 1983 S. Karger AG, Basel

Fosfomycin: Interpretation of Inhibition Zones Obtained with the Bauer-Kirby Agar Disk
Diffusion Susceptibility Test
Traub W.H. · Spohr M.

Author affiliations
Institut für Hygiene und Mikrobiologie, Universität des Saarlandes, Homburg a. d. Saar, FRG
Corresponding Author
Walter H. Traub, Institut für Hygiene und Mikrobiologie, Haus 43, Universität des Saarlandes,
Homburg a. d. Saar (FRG)

Published online: September 08, 2009

Number of Print Pages: 5

Number of Figures: 0
Number of Tables: 0

ISSN: 0009-3157 (Print)

eISSN: 1421-9794 (Online)

For additional information: https://www.karger.com/CHE