— Tage torte + 10 1 12, 13, 16. 16. "7 18. 19. CLINICAL CHEMISTRY By Apollon et.al. CHAPTER 1 - Chemistry Questions Clinical Chemistry Questions A volumetric pipette has an aceuraey ot: A. 4:10 B. 1:100 6.42800 ©. 1:1000 ‘A pipette with a bulb Close fo the delivery tj is used for viscous fluids and is called a; 2 Mot pipette ©. Lewss-Oann piparte B. Volumatric pipette 2, Ostwald-Fatin pipette The etched rings on the top of a pipette means A. The pipette should be alowed fo drain anc the last drop should romain in the pipetie 8. The last drop ts to be blown oul after the pipattes drains C. The pipatte is color cones D. The pipette is a volumetric pipette ‘Standard solution trom which 99.95% of the che mical can be retrieved are referred to as: % Secondary standaras, G. Lyophilized standarss B. Primary standards D. Preset standards \When preparing solutions: és A percant solutien can bé prepared from volumetric solution EL A Volumlaric solution can be prepared trom a perceat solution ©. Atriple beam balance end cylindar ere necessary in ine preparation of any type of solution D._Only an analytical baianee.can be used in solution preparatian Solution in which the maleeules of salute in Solution ere: in equilibrium with excess undissolved molecules is referred to as: & Dilule B. Concentrated 2, Saturated D. Supersatursted Pure water has a pH of: A 68 5.7.0 o74 5.90 4 4x10°N solution of hdtookone ata (69 ea 1 pH of: & 4 Be c.8 D.12 ‘The statistical term (hal most spacifically dese”bge analytical precision ig the: A. Mode 5. Mean C Median D. Coeticient of vanation Quality control should be used with all proceciures to detemmine: A. Accuracy B. Reliataty C, Piscision —D. Coefficient wf variation DELETED A procesiure has @ 2 SD var ation from 2 mean value, Hav man}: vaiLos from a normal papultstion will the 2.SC include: A. 68.27% 8. 84.76% 6. 85.45% 2, 98.73% Material with physical and chemical properties closely resembling the test specimen and cantaining concentrations of the substances being moasurod is known as: Aa” Conteol 6, Standard . Calibrator D. Reference solution (Optical density, according to Beer's law, is: 4 Inversaly proportional to the concentration & Direct propartional to the concertration ‘G. Proportional to the square of the concentration ©, Proportional to the square root of the concentration ‘ The ditlorence between soruin and plasma is that serum aves not Contain: 4 Thrombin 8. Fibrin Fibrinogen ©. Calcium Two control sera are desirable for esc general chemistry procedure, Which of these combinations would be sppropriate? 4. Mean of normal range and abnormal (high) ©. Low nowmal range and abnormal (ow) 8. High normal range and abnormal (high) D. Abnormal flow) and ebnormal (high) . Sodium Flugride is used in specimen collection ta: A. Prevent glyectysis C.Chelate catium 8. Preven! conversion of prothrombin io thrombin ©. Bind calcium ‘Tre concentration of oxalate recommended to be used as an anticoagulant, in mgimi. blood, is: A 12 Po BL2d 0.46 0.68 Etiylenectamine \etraacetic acid (EDTA) works 28 anticoagulant by: A Chelating calcium 8. Preventing conversion of prothrombin to thrambin €, Forming an insoluble complex with calcium D. Binding magnesiumRO TRE Venininelre site fora routine puncture is commonly cleaned with: A. 904 alcohol G. 70% aleanol B. BETADINE (Purdue-Frederick) 1B. Quatomary amenenium compounds 2) The one precaution (a be followed with a s, ecimen for Lisrubin determination is to: A. Refrigerate . Protect from light B. Cap and refiger B, Freeze immediately 22, Which of these substances cannot be preserved by freezing? A. Blaod urea nitrogen Lactic denydranenase 1h Grnativs Rie eneeyins 1 Treat el peepee EHNA TN warty flys 1 YORE A. Diumtal variation €. Ellect of meuication A Chane af eonsumpion (Yvette patos: tebe wie ‘A. Albumin 8. Beta giouuins ——C. Gamma globulins -_D. Histones 25, The alphs-amino acids constitute the basic b: éding blocks of proteins. The amino acids are joined together to form a chainlike structure through: unten tion OF Hon ‘A. Disulfide bonding =. Hydfagen bonding C. Covalent bonding _D. Peptide bonding 25. Which cf the four elements in pvoteins differentiate this class of substances from carbohydrates and lipids? A. Carbon B. Hydrogen C. Nitrogen 1D, Oxyger 27. Which amine acid cannot rotate polarized ligt? A. Gysune 8. Glycine G. Histidine D. Thionine 28. Proteins may become denatured whan subjected to meuhanical agitation, heat, of exireme chemical treatment. ‘Denaturatian of proteins raters to an: ‘A. Alteration in primary structure Alteration in tertiary structure B. Alteration in secondary structure D. increase in sohubilty 29, The hernogkabin measurement technique employed for ood donors is A. Refractive index . Flotation technique of Philips &. Hemoglobin electrophoresis 1D. Falling drop technique 30, The ration oF velocities of ight in twa different media retars to the: A. Density gradient C. Rotation of powsnzed tant B. Refractive index . Uitaviolet absorption 31. The most anodic protein on electrophoresis at pH 8 6 is, A. Alpha; globulin B. Albumin ©. Beta globulin D. Gamma globulin 32. Proteins are dipolar or zwiltenon cempeunds containing bath positive and negative charges. When a p-otein is ut is isoalnetie paint. the peiein sill have A Ul este tune Mp tul 20 (Nel genitive cheno Dad mgeives stoi 3a, Svedberg {S) number refer 19 protein: A. Electrophoresis 'B. Flotation. ©. Precipitation D, Utvacentiifugation 84 The macroglobulins helong lo what sedimeniition class.’ A Ass u/08 ot bo 19.08 35. As urine i heated, a prociilale appears al 60 C and disaproars al 100 G. The substance praesent i ‘A. Macroglobulin B. Cryagiobeiy C. Bence Jones prote D Protease 35. The prucess of separating albumin from globulins using sodium sulfate is know as: A. Floatation B, Protein precipitation C. Salting out D. Uitracentafugation ‘BY. The conversion of protein ritrogen contan. to protein content depends on the factor: A 625 B.6.54 C.663 Dia 88. Which of he folowing NOT tue of ihe blurt reaction? lar fet a roms GC. {5 selalively free from interference by Kpids and henniaglobut D. Is insensitive to the low protein levels of urine 39. In acute venal failure which nonprotein nitrogen rises the fastest? B. Blood urea nit © Creatinin« fo purge ths prorenrud i eatar for wane lye A. Wlends itself to mana! and automawed procedures Lest 8M never binds with alphe and bea globulins © ‘Lea bo cmployedt vail nepariniaed psi D._ These is less interterence trom pigment ‘41. Which reagent is empioyed in the serum protsin determination? A. Molyosenum blue B. Ferrferecyanite —C. Resorcinol-HCi_—_, Biurat 42 Homaty ct howl Not bo used for tote! protein beenuse: A. Hemugiolan is absorbed al the same wavelengin es protein af bluist reeqent 5 Ofe sated protein nmoumts in rad blood cells as compared to serum Hemopiobin reacts wits biuret reagent The vale wail bo taal lower 43 Turbidity fn seruny is associated with the presence of A Cholesterol 8, Chylomerans G Fee tally aads §——D. Total lips 496, Clycoproteins and mucoproteins are wsvally bound to A. Lactesa and sucrose ©. Galactose and mannose. B. Lactose and maltose 1B. Givcose and sucrc se 445, Ail of the following are glycoproteins, except: A. Ceruloplasmin B. Follice stimulating hormene C. Fibrinogen 0. Cryoglobulin D, Creatine ene PeesRO TRE Venininelre site fora routine puncture is commonly cleaned with: A. 904 alcohol G. 70% aleanol B. BETADINE (Purdue-Frederick) 1B. Quatomary amenenium compounds 2) The one precaution (a be followed with a s, ecimen for Lisrubin determination is to: A. Refrigerate . Protect from light B. Cap and refiger B, Freeze immediately 22, Which of these substances cannot be preserved by freezing? A. Blaod urea nitrogen Lactic denydranenase 1h Grnativs Rie eneeyins 1 Treat el peepee EHNA TN warty flys 1 YORE A. Diumtal variation €. Ellect of meuication A Chane af eonsumpion (Yvette patos: tebe wie ‘A. Albumin 8. Beta giouuins ——C. Gamma globulins -_D. Histones 25, The alphs-amino acids constitute the basic b: éding blocks of proteins. The amino acids are joined together to form a chainlike structure through: unten tion OF Hon ‘A. Disulfide bonding =. Hydfagen bonding C. Covalent bonding _D. Peptide bonding 25. Which cf the four elements in pvoteins differentiate this class of substances from carbohydrates and lipids? A. Carbon B. Hydrogen C. Nitrogen 1D, Oxyger 27. Which amine acid cannot rotate polarized ligt? A. Gysune 8. Glycine G. Histidine D. Thionine 28. Proteins may become denatured whan subjected to meuhanical agitation, heat, of exireme chemical treatment. ‘Denaturatian of proteins raters to an: ‘A. Alteration in primary structure Alteration in tertiary structure B. Alteration in secondary structure D. increase in sohubilty 29, The hernogkabin measurement technique employed for ood donors is A. Refractive index . Flotation technique of Philips &. Hemoglobin electrophoresis 1D. Falling drop technique 30, The ration oF velocities of ight in twa different media retars to the: A. Density gradient C. Rotation of powsnzed tant B. Refractive index . Uitaviolet absorption 31. The most anodic protein on electrophoresis at pH 8 6 is, A. Alpha; globulin B. Albumin ©. Beta globulin D. Gamma globulin 32. Proteins are dipolar or zwiltenon cempeunds containing bath positive and negative charges. When a p-otein is ut is isoalnetie paint. the peiein sill have A Ul este tune Mp tul 20 (Nel genitive cheno Dad mgeives stoi 3a, Svedberg {S) number refer 19 protein: A. Electrophoresis 'B. Flotation. ©. Precipitation D, Utvacentiifugation 84 The macroglobulins helong lo what sedimeniition class.’ A Ass u/08 ot bo 19.08 35. As urine i heated, a prociilale appears al 60 C and disaproars al 100 G. The substance praesent i ‘A. Macroglobulin B. Cryagiobeiy C. Bence Jones prote D Protease 35. The prucess of separating albumin from globulins using sodium sulfate is know as: A. Floatation B, Protein precipitation C. Salting out D. Uitracentafugation ‘BY. The conversion of protein ritrogen contan. to protein content depends on the factor: A 625 B.6.54 C.663 Dia 88. Which of he folowing NOT tue of ihe blurt reaction? lar fet a roms GC. {5 selalively free from interference by Kpids and henniaglobut D. Is insensitive to the low protein levels of urine 39. In acute venal failure which nonprotein nitrogen rises the fastest? B. Blood urea nit © Creatinin« fo purge ths prorenrud i eatar for wane lye A. Wlends itself to mana! and automawed procedures Lest 8M never binds with alphe and bea globulins © ‘Lea bo cmployedt vail nepariniaed psi D._ These is less interterence trom pigment ‘41. Which reagent is empioyed in the serum protsin determination? A. Molyosenum blue B. Ferrferecyanite —C. Resorcinol-HCi_—_, Biurat 42 Homaty ct howl Not bo used for tote! protein beenuse: A. Hemugiolan is absorbed al the same wavelengin es protein af bluist reeqent 5 Ofe sated protein nmoumts in rad blood cells as compared to serum Hemopiobin reacts wits biuret reagent The vale wail bo taal lower 43 Turbidity fn seruny is associated with the presence of A Cholesterol 8, Chylomerans G Fee tally aads §——D. Total lips 496, Clycoproteins and mucoproteins are wsvally bound to A. Lactesa and sucrose ©. Galactose and mannose. B. Lactose and maltose 1B. Givcose and sucrc se 445, Ail of the following are glycoproteins, except: A. Ceruloplasmin B. Follice stimulating hormene C. Fibrinogen 0. Cryoglobulin D, Creatine ene Pees— Tage torte + 10 1 12, 13, 16. 16. "7 18. 19. CLINICAL CHEMISTRY By Apollon et.al. CHAPTER 1 - Chemistry Questions Clinical Chemistry Questions A volumetric pipette has an aceuraey ot: A. 4:10 B. 1:100 6.42800 ©. 1:1000 ‘A pipette with a bulb Close fo the delivery tj is used for viscous fluids and is called a; 2 Mot pipette ©. Lewss-Oann piparte B. Volumatric pipette 2, Ostwald-Fatin pipette The etched rings on the top of a pipette means A. The pipette should be alowed fo drain anc the last drop should romain in the pipetie 8. The last drop ts to be blown oul after the pipattes drains C. The pipatte is color cones D. The pipette is a volumetric pipette ‘Standard solution trom which 99.95% of the che mical can be retrieved are referred to as: % Secondary standaras, G. Lyophilized standarss B. Primary standards D. Preset standards \When preparing solutions: és A percant solutien can bé prepared from volumetric solution EL A Volumlaric solution can be prepared trom a perceat solution ©. Atriple beam balance end cylindar ere necessary in ine preparation of any type of solution D._Only an analytical baianee.can be used in solution preparatian Solution in which the maleeules of salute in Solution ere: in equilibrium with excess undissolved molecules is referred to as: & Dilule B. Concentrated 2, Saturated D. Supersatursted Pure water has a pH of: A 68 5.7.0 o74 5.90 4 4x10°N solution of hdtookone ata (69 ea 1 pH of: & 4 Be c.8 D.12 ‘The statistical term (hal most spacifically dese”bge analytical precision ig the: A. Mode 5. Mean C Median D. Coeticient of vanation Quality control should be used with all proceciures to detemmine: A. Accuracy B. Reliataty C, Piscision —D. Coefficient wf variation DELETED A procesiure has @ 2 SD var ation from 2 mean value, Hav man}: vaiLos from a normal papultstion will the 2.SC include: A. 68.27% 8. 84.76% 6. 85.45% 2, 98.73% Material with physical and chemical properties closely resembling the test specimen and cantaining concentrations of the substances being moasurod is known as: Aa” Conteol 6, Standard . Calibrator D. Reference solution (Optical density, according to Beer's law, is: 4 Inversaly proportional to the concentration & Direct propartional to the concertration ‘G. Proportional to the square of the concentration ©, Proportional to the square root of the concentration ‘ The ditlorence between soruin and plasma is that serum aves not Contain: 4 Thrombin 8. Fibrin Fibrinogen ©. Calcium Two control sera are desirable for esc general chemistry procedure, Which of these combinations would be sppropriate? 4. Mean of normal range and abnormal (high) ©. Low nowmal range and abnormal (ow) 8. High normal range and abnormal (high) D. Abnormal flow) and ebnormal (high) . Sodium Flugride is used in specimen collection ta: A. Prevent glyectysis C.Chelate catium 8. Preven! conversion of prothrombin io thrombin ©. Bind calcium ‘Tre concentration of oxalate recommended to be used as an anticoagulant, in mgimi. blood, is: A 12 Po BL2d 0.46 0.68 Etiylenectamine \etraacetic acid (EDTA) works 28 anticoagulant by: A Chelating calcium 8. Preventing conversion of prothrombin to thrambin €, Forming an insoluble complex with calcium D. Binding magnesium