River Hitt HiGH SCHOOL TDIO1 Clarksville Pike» Claehsville, MD 21029 + 410313 !ARD COUNTY 106 + www hepss.ong/hhs (410-313 Gifted and Talented Program Product Abstract Each student in the Independent Research Program must carry out an authentic, advanced research project, which is capable of being evaluating its quality, authenticity, and novelty. The following information written by the student provides an overview of the product proposal as planned. ‘Student: Diana Oh Date: May 29, 2019 Research Title: Can I Eat That? Finding the Allergy Solution Purpose: To examine the ethics and efficacy of oral immunotherapy in immunoglobulin-E mediated allergies and to assess oral immunotherapy’s potential as a clinical treatment for allergies. Product/Outcomes: A research paper and a website were produced as a result of the research conducted. A display board was presented to increase awareness of oral immunotherapy and allergy treatment. A presentation was given. to the advanced placement biology class to share findings. Novelty of Product: Although food allergies have increased in incidence for the last twenty years, there are no approved clinical treatment, other than avoidance. An upcoming treatment for immunoglobulin-E mediated food allergies is oral immunotherapy; however, it comes with high risk. This research analyzes oral immunotherapy as @ potential clinical treatment for food allergies. ‘Audience: The intended audience of the product is allergy patients, families that need to gain awareness of the subject, and scholarly researchers of the subject. Process: 1. Intensively researched topics related to food allergy treatment, eventually decided on oral immunotherapy as my topi 2. Located an advisor: Ms. Kim Mudd, the Senior Research Nurse/Program Coordinator at Johns Hopkins University-Division of Pediatric Allergy. 3. Gathered and reviewed articles, scholarly journals, and clinical studies focused on the topic, and compiled over 25 annotations of scholarly articles. 4, Conducted interviews with Ms. Mudd and Dr. Glenn M. Silber M.D, an allergist at the Allergy & ‘Asthma Center of Central Maryland in order to gain more information and clarify any questions. 5. Synthesized all information into a paper. 6. Gathered data with a literature review of three studies observing the effect of oral immunotherapy on adolescents with immunoglobulin-E mediated peanut allergies. 7. Presented finding with a visual display board and website in regards to the topic. Composed an scholarly article outlining research and submitted to the Young Sci Presented finding to peers in an advanced placement biology class. snes fae tay ‘Student Signature 2019