BOTPOCHI K FOCYJAPCTBEHHOMY BbIITYCKHOMY 9K3AMEHY no mmexusommem Gores (ENGLISH) 1. Acute dysentery. Clinical manifestations. Classification. Early diagnosis and differential diagnosis based on clinical and epidemiological data, Laboratory diagnosis. Organization of the examination and treatment of patients at home. . 2, Salmonellosis. Clinical manifestations. Classification, Symptoms of clinical variants of gastrointes- tinal form (gastritis, gastroenteritis, gastroenterocolitis). Symptoms of generalized (typhoid-like and septicopyemic forms). Prognosis. Laboratory diagnosis: bacteriological and_ serological. Treatment. Indications for hospitalization. Organization of the treatment of patients at home. Re- gime, diet. Rehydration therapy. Antibacterial treatment, 3, Cholera, Clinical manifestations depending on the degree of dehydration, complications, prognosis. Diagnostics. Technique of taking ‘material for bacteriological investigation. Differential diagnosis. WHO rehydration scheme, etiotropic treatment. 4. Foodbomne toxico-infection. Epidemiological, clinical and laboratory criteria for diagnosis. Deter- mination of the degree of dehydration. Indications for hospitalization. Organization of the exami- nation and treatment of patients at home. 5. The principles of acute intestinal infections treatment (invasive, secretory and osmotic types of diar- thea). Rehydration, antibiotic therapy. Prevention. 6. Viral hepatitis. Classification. Periods of the disease. Early diagnosis based on clinical, epidemio- logical and laboratory data. Criteria for severe course of viral hepatitis. Delta - infection. 7. Diagnosis of viral hepatitis. Clinical and laboratory syndromes: cytolytic, cholestatic, mesenchymal inflammatory, liver failure. Specific diagnosis. Principles of viral hepatitis treatment. 8. Leptospirosis. Clinical manifestations. Clinical classification. Icteric and anicteric variants of the disease. Complications. Prognosis. Diagno: Importance of epidemiological history. Bacterio- logical and serological diagnostic methods. Differential diagnosis. Etiotropic, pathogenetic and symptomatic therapy. 9. HERS. Clinical manifestations. Self-limited course of disease, Dynamics of the main symptoms. Haemorrhagic manifestations. Renal syndrome. Variants of the disease. Complications. Prognosis. Diagnostics. Clinical and epidemiological diagnosis. Laboratory diagnostic methods. Differential diagnosis, Treatment, Pathogenetic and symptomatic therapy. 10. Lyme borreliosis. Clinical manifestations. Stages of the disease. Skin, nervous system, heart and joints lesions. Laboratory diagnostics. Treatment. Etiottopic therapy according to the disease stag- ‘es. Post-exposure prophylaxis. 11. Erysipelas. Clinical manifestations. Classification. Symptoms of intoxication. Erythematous, ery- thematous-bullous, erythematous-hemorthagic, bullous-hemorthagic forms. Criteria of severity. Complications. Prognosis. Diagnostics. Treatment, Indications for hospitalization. Organization of ‘treatment at home. Etioptopic and pathogenetic treatment. Prophylaxis of relapses. 12, Plague. Clinical forms. Prognosis. Diagnosis: bacteriological, serological. Technique of taking ma- terial for bacteriological examination. Treatment: need for hospitalization, etiotropic and pathoge- netic therapy. Rules of discharge of the patients from hospital. Prevention. 13, Anthrax. Clinical manifestations. Classification of the clinical forms. Clinical characteristics of cu- taneous and septic forms. Complications. Prognosis. Laboratory diagnosis: bacterioscopy, bacterio- cy biological, serological, Treatment. Etiotropic, pathogenetic and symptomatic therapy. Pre- vention. 14, Rabies. Clinical manifestations. Characteristics of the disease stages. Atypical forms of rabies. Prognosis. Diagnostics. Value of clinical, epidemiological and laboratory data. Treatment. Nursing, and symptomatic therapy of the patients. Prevention: nonspecific and specific. 15, Lassa, Marburg, Ebola fevers. Etiology. Epidemic features. Clinical manifestations. Diagnostics. ‘Treatment. Prevention. 16, Malaria. Clinieal manifestations. Characteristics of P.vivax, P.ovale, P.malariae, P falciparum ma Jaria. Early and late relapses. Complications. Prognosis. Diagnosis: microscopy, methods of anti- gens detection, Treatment, Basic antimalarial chemotherapy, mechanisms of drugs action, Preven-ations of uncomplicated influenza, Criteria of Value of clinical and epidemiological data. La- 17. Influenza. Clinical classification. Clinical ma severity. Complications, Prognosis. Diagnosti boratory diagnosis: virological, serological. 18. The principles of acute respiratory viral infections treatment. Ind tropic treatment of influenza: neuraminidase inhibitors, rimantadine, ant munoglobu- lin, interferon. Principles of pathogenetic therapy. Indications for use of antipyretics, antibiotics. Prevention, Individual prevention. Specific prophylaxis of i 19. HIV infection. Etiology, properties of the virus: genetic variability, stability in the environment. Epidemiology. Sources of infection. Mechanism and routes of transmission. Risk groups. Patho- genesis. Mechanisms of immunological disorders development. Activation of opportunistic infec- tions and invasions pathogens, Pathomorphology. 20. HIV infection. Clinical manifestations. Stages of HIV infection, Primary infection. Classifications of HIV infection. Characteristics of main opportunistic infections. Diagnostics. Laboratory meth- ods: serological (ELISA, WB and others), virological, study of the cellular immunity status. Treatment, Etiotropic therapy. Treatment of opportunistic infections, invasions. Measures of per sonal and social prevention. 21. Differential diagnosis of tonsillitis (angina). Infectious diseases with oropharyngeal lesions: strep- tococcal sore throat, diphtheria, infectious mononucleosis, scarlet fever, gerpangina, tularemia. Clinical, epidemiological and bacteriological diagnostics. Oropharyngeal lesions in non-infectious diseases, systemic blood diseases. Prehospital examination of patients with oropharyngeal lesions. Indications for hospitalization, 22. Differential diagnosis of jaundice. Infectious diseases with jaundice syndrome: viral hepatitis, lep- tospirosis, infectious mononucleosis, Yersinia infection, parasitic liver diseases, malaria, Groups of non-infectious diseases: toxic hepatitis (including drug-induced), alcoholic liver disease, chronic inflammatory liver and biliary tract diseases, liver cirrhosis, hereditary pigment hepatoses. 23. Differential diagnosis of infectious diseases associated with exanthema: measles, scarlet fever, measles, epidemic typhus and Brill-Zinsser disease, Yersinia infection, meningococcemia, hemor- thagic fevers, typhoid, paratyphoid. Non-infectious exanthema: skin diseases, drug reactions, cuta- neous manifestations of connective tissue diseases, hemorrhagic diathesis. Pre-hospital examina- tion of the patient with exanthema. Indications for hospitalization, 24. Acute infectious disease with high and prolonged fever: typhoid fever and paratyphoid, brucellosis, epidemic typhus, malaria. Differential diagnosis with somatic diseases with high and prolonged fe- ver: purulent infections, sepsis, pulmonary and extrapulmonary TB, collagenoses, systemic blood diseases, tumors, syphilis, drug reactions. Prehospital examination of a patient with high and pro- longed fever and suspected infectious disease. Indications for hospitalization. 25. Infectious diseases of the CNS. Meningitis syndrome, meningoencephalitis and infectious- toxic encephalopathy. Bacterial and aseptic meningitis, diagnostics, medical approach. Differential diag- nosis of meningitis. 26. Diarrheal syndrome. Differential diagnosis of infectious and non-infectious diarrhea. Nosologic and syndromal diagnosis of infectious diarrhea. Invasive diarrhea, secretory, mixed (dysentery, cholera, salmonellosis, etc.), their pathogenetic mechanisms, syndromic and etiotropic treatment Prevention of infectious diarrhea. 27. Clinical manifestations, treatment principles of hypovolemic shock. Calculation of the fluid vol- ume, phases of correction. 28. Clinical manifestations, treatment principles of infectious-toxic (septic) shock. Pre-hospital thera- Py. 29. Clinical manifestations, treatment principles of brain edema. Protection of the cerebral cortex, de- hydration. 30. Meningococcal infection. Clinical manifestations. Classification of meningococcal infection forms. Clinical manifestations of menincococcal nasopharyngitis, meningococcal meningitis, meningoen- cephalitis, meningococcemia, Complications. Outcomes. Diagnosis: bacterioscopy, bacteriological, serological. Etiotropic and pathogenetic therapy. Principles and tactics of antibiotic therapy. Pre- vention. Post-exposure prophylaxis of disease, detection and treatment of meningococcal carriers.