1. Which of the following amino acids has a polar side chain?

A. A
B. S
C. I
D. P
E. V

2. Which of the following amino acids has a side chain that contains a sulfur atom?

A. Leucine.
B. Alanine.
C. Phenylalanine.
D. Cysteine.
E. Valine.

3. Choose the peptide that is, overall, the most non-polar (i.e. all of the amino acids are classified as being
nonpolar).

A. PALIV
B. ALIVE
C. KEDIR
D. LIVMD
E. PHILK
4. Using the single letter designation for amino acids, which of the following is the correct single letter
designation name from N- to C- termini for the polypeptide shown above at neutral pH?

A. IASK.
B. IASR.
C. LASR.
D. LASK.
E. IATR.

5. A competitive enzyme inhibitor has which following effect?

A. decreases Vmax and increases KM.

B. decreases Vmax and has no effect on KM.
C. has no effect on either Vmax or KM.
D. decreases KM but has no effect on Vmax.
E. increases KM but has no effect of Vmax.
6. Which of the following statements defines correctly a concept related to pH?

A. The pI of histidine is calculated on the basis of 2 pKa values.

B. In water, an acidic solution has a pH < 7.0.
C. The value pH = [H+]
D. The pH ranges between 7.2 and 7.5 in every compartment of the human body.
E. In general, carboxyl groups are protonated at neutral pH.

7. The initial addition of the core oligosaccharide to a glycoprotein occurs ….

A. After the protein has been released from the ribosome to the cytoplasm.
B. Occurs in multiple steps, with one sugar added at a time.
C. Through transfer from dolichol phosphate
D. In the Golgi complex
E. After all O-linked sugars are added
8. What is the composition of the most common form of adult hemoglobin?

A. delta2beta2.
B. alpha2epsilon2.
C. alpha2delta2.
D. delta2gamma2.
E. alpha2beta2.

9 Which of the following characteristics accurately describes a feature of mammalian globin proteins?

A. Mb has a higher affinity for O2 that Hb.

B. The Hill coefficient for adult Hb is 1.0
C. Decreasing pH correlates with increased affinity of Hb for pO2.
D. The molar stoichiometry of binding oxygen to Hb is 1:1.
E. The [2,3-BPG] in RBCs is lower for a person living at an altitude of 8,000 feet vs. someone at sea level.
1. B

2. D

3. A

4. D

5. E

6. A

7. C

8. E

9. A