Vet Clin Pathol. 1984;13(1):13-7.

Fine needle aspiration cytology and histologic correlation in

canine tumors.
Griffiths GL1, Lumsden JH, Valli VE.
Author information
Abstract
Fine needle aspiration biopsy was performed on 147 skin tumors in 119 dogs over a 4-year
period. Both air-dried smears (Wright's stain) and wet-fixed smears (Papanicolaou's stain) were
prepared from the aspirates from each tumor and the cytological diagnosis was correlated with
histology. In 105 tumors, the cytological and histological interpretations agreed. Histologically,
there were 36 stromal tumors, including 19 fibrosarcomas and nine hemangiosarcomas.
Cytologically, 12 of the fibrosarcomas and five of the hemangiosarcomas were interpreted
correctly as malignant tumors. All 11 melanomas and all 37 mast cell tumors were identified
correctly cytologically, while nine of the 11 squamous cell carcinomas, 15 of 21 adenocarcinomas
and eight of 19 mammary carcinomas were interpreted as malignant using aspiration biopsy. The
fine-needle technique also identified 16 dogs with metastases to the regional lymph nodes before
surgical biopsies were undertaken. Benign tumors were incorrectly described as malignancies in
only three cases.
 CYTOLOGY AND HISTOLOGY OF CANINE NEOPLASMS
AND THEIR CORRELATION
Sudha Rani Chowdary. CH*, M. Raghunath, P.Vidya Sagar and P. Ravi Kumar
Department of Teaching Veterinary Clinical Complex,
NTR college of Veterinary Science, Gannavaram, Andhra Pradesh.

Fine needle aspiration / impression cytlogy was performed on 36 cases of canine

neoplasms during a period of one and half year. All the smears were stained with
Leishman’s stain and the cytological diagnosis was correlated with histology. Overall,
80.5% concordance was found between cytologic and histologic diagnosis. Correlation
was 100% for transmissible veneral tumors (16 cases), mastocytomas (2 cases), lipomas
(3 caes), fibroma (1 case) and mixed mammary gland adenoma (1 case). Correlation was
80% in cases of mammary gland adenocarcinomas (5 cases) and 67% in squamous cell
carcinomas (3 cases). Correlation was 0% in cases of ceruminous gland adenoma (1
case), mammary gland complex carcinoma(1 case), liposarcoma (1 case), hemangioma (1
case) and sertoli cell tumor (1 case). Hence, cytologic diagnosis can be employed for
diagnoses of most of the canine neoplasms which is less expensive, quick and less
invasive.