Penguian Brasileira cm Odontopediatria © Clinica Integrade 4018, 18(1}et071 DOT heeps//ds dot ong/¥0.4094/PROCL 2018.403.78 ISSN 1510-0501 “ORIGINAL ARTICLE ‘Comparison Between Nickel and Chromium Levels in Serum and Urine in Patients Treated with Fixed Orthodontic Appliances: A Longitudinal Study ‘Susilowati Mudjar', Muhammad Haran Achm “Lecturer, Department of Orthodontics, Faculty of Dentistry, Hasunuddin University, Indonesia, Lecturer, Department of Podiatric Dentistry, Faculty of Dentistry, Hasanuddin University Indonesia. ‘Author to whom correspondence should be addressed: Muhammad Harun Achmad, Pediatric Dentistry Department, Faculty of Dentistry, Hasanuddin University, Makassar, South Sulawesi, Indonesi. Phone: +02 35242739400. F-mal: hrunachmader@igmail.com. ‘Academic Editors: Alessandro Leite Cavateanti and Wilton Wilney Nascimento Paditha Received 06 April 2018 / Accepted: 22 June 2015 / Published: 27 June 2018 Noaract Objective: To compare levels of nickel and chromium in serum and urine in orthodontic patients treated with fixed orthodontic applisnces, Material and Methods: Nickel and ‘chromium jon concentration were measured in scrum and urine of twenty patients (13 females and males, aged 17-28 years old) who had fixed orthodontic treatment using Coupled Plasma-Atomic Emission Spectroscopy, The samples were taken before ‘catment (Bascline) two months, and six months later during treatment. Data were analyzed using repeated ANOVA, Bonferroni post-hoc teat, and paired t-tests The level of significance was sct at 5%. Results: Average scram nickel level changed from 6.420 ppb to 6.855 ppb. Average serum chromium level changed from 5.05 ppb to 5.505 ppb in 6 months. Average urinary nickel level changed fiom 5.920 ppb to 3.610 ppb. Average urinary chromium level changed from 6.370 ppb to 6.520 ppb in 6 month. There was x statistically significant diferenee in serum (p<0.001) and urinary chromium (p=0.007) levels between observation times. Conclusion: Orthodontic ‘treatment might raise both urinary and serum nickel levele. but the dillerences were not statistically significant the alterations in chromiumlevels were not consistent; nickel [evels were higher in serum than in urine; chromium levels were higher in urine than in Keywords: Orthodontic Appliances; Serum; Orthodontic Brackets, | ae a