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Week 4 Pharmacology
Week 4 Pharmacology
Lignocaine
Fleccanide
Beta blockers
Amiodarone
Verapamil
Diltiazem
Others:
Adenosine: Stops calcium current and causes inward Potassium current, hyperpolarising the cells
and suppressing action potentials.Works mainly on the AV node, a little on the SA node
Digoxin: Inhibits Na/K/ATPase, which decreases activity of the Na/Ca exchanger, resulting in net
increased calcium levels inside myocardial cells. Slowing HR and increasing contractility w/o
increasing cardiac work
Vasopressors:
Adrenaline: A and B agonist. Vasoconstrictor (A) and cardiac stimulant (B1) (Does act at B2 so causes
vasodilation to muscles, net drop in TPR