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Emergency Medicine Notes, Cont
Emergency Medicine Notes, Cont
What to do for pulseless VTach After each step, do 5 cycles of CPR followed by pulse and rhythm check before
going on to next step.
1. Defibrillate
2. Defibrillate again
3. Epinephrine
4. Defibrillate
5. Amiodarone
6. Defibrillate
7. Epinephrine
What to do for VFib After each step, do 5 cycles of CPR followed by pulse and rhythm check before
going on to next step.
1. Defibrillate
2. Defibrillate again
3. Epinephrine
4. Defibrillate
5. Amiodarone
6. Defibrillate
7. Epinephrine
What to do for stable SVT Control rate with vagal maneuvers. If they don’t work, do adenosine followed by
other AV node blocking agents
What to do for stable a-fib Control rate (diltiazem or BB) and anticoagulate if it’s been > 48 hours. Can do
elective cardioversion right away if it’s been < 48 hours. Otherwise must first do a
TEE or anticoagulate
What to do for bradycardia Atropine. If it doesn’t work, then give transcutaneous pacing, dopamine, or
epinephrine
Abdomen pain: Parietal pain vs. Parietal: sharp, focal, guarding. Often don’t want to move.
visceral pain Abdomen: Midline or diffuse, crampy, achy. Often unable to lie still.
How to dx appendicitis Clinical. Look at WBC for labs, but no imaging is needed unless dx is uncertain
(e.g., patient has an appetite). If imaging is going to be done, do CT with oral and
IV contrast. Can also do ultrasound.
Parkland formula for fluids in Applies to 2nd and 3rd degree. Give 4 mL per kg x % BSA. Give ½ in first 8 hours
burns and ½ in the next 16. Adjust to maintain UOP of at least 1 mL/kg/hr
Burn prophy abx? Topical silver sulfadiazine when epidermis is not intact. Orals don’t really help.
When to transfer to a burn - 10-50 years: > 20% BSA. If younger or older, > 10% BSA
center? - Any 2nd-3rd degree burns involving face, hands feet, genitals, perineum,
major joints.
- Any circumferential burns
- Chemical, electrical, lighting
- Inhalation injury
Issue to be aware of with O2 sat can read normal if the pulse ox doesn’t distinguish carboxyhemoglobin
carbon monoxide poisoning and
pulse ox
Rodent bite Local wound care. They don’t carry rabies and they have a low risk of infection
Rabies prophy in a vaccinated Give 2 more doses of vaccine (don’t need IvIG or 4 course vaccine)
person
Tetanus - clean: give tetanus toxoid vaccine if < 3 lifetime vaccinations and last one >
- Clean wound 10 years ago
- Major/dirty wound - dirty wound: give tetanus toxoid if last one > 5 years ago. Give IVIG if had
< 3 tetanus vaccines ever
Central cord syndrome burning pain and paralysis of upper extremities, lower extremities are okay.
Commonly seen in the elderly with forced hyperextension of the neck
Respiratory quotient Ratio of O2 consumed to CO2 produced as fuel is burned. carbs have a ratio close
- what is it? to 1, protein 0.8, fat 0.7. Normal RQ is 0.8 due to a mix of dietary intake.
- What is the ratio for
proteins, fats, carbs?
Biggest danger with median nerve and/or brachial artery entrapment
supracondylar fracture of the
humerus
Approach to massive 1. Urgent brochoscopy for dx and tx (e.g., cautery, balloon tamponade)
hemoptysis 2. Pulmonary arteriography for embolization
3. thorocotomy
Management of duodenal Conservative - NG suction and parenteral nutrition. Should resolve in 1-2 weeks. If
hematoma not, consider surgery.
Management of meniscal injury Persistent mechanical symptoms → MRI. PRobably need surgery (not true for MCL
tears)
Appendicitis management lap appy if obvious. If not classic, imaging with CT or ultrasound
What dose of prednisone and > 20 mg for > 3 weeks. No risk if < 5 mg. Intermediate risk 5-20.
time frame of use raise concern
for adrenal suppression?
Mnemonic for brachial plexus Rugby Teams Drink Cold Beer - roots, trunks, divisions, cords, branches
roots, cords, etc
When to avoid oro-tracheal Significant facial injuries. It’s okay with cervical spine injuries. If OT intubation isn’t
intubation an option, the next step is cricothyroidotomy.
Severe acute back pain, Ruptured AAA - the bleed can go into the retroperitoneum, lead to increased
hypotension, hematuria pressure that causes venous congestion in retroperitoneal structures like the
bladder. Can cause gross hematuria!!
Biostatistics:
Disease No disease
Exposure/positive test a b
No exposure/negative test c d
Likelihood ratio: positive and negative Likelihood ratios are the odds of disease if a test is positive or
negative. Diseased people like to go on top for both equations
Positive Likelihood ratio = (a/b) = true positives/false positives =
diseased people with positive result/nondiseased people with a positive
result
What happens to PPV and NPV when PPV and prevalence decrease together and NPV and prevalence are
prevalence decreases opposite.
Odds ratio Odds that a diseased person was exposed/odds that a non-diseased
person was exposed (= a/c divided by b/d = ad/bc)
Attributable risk and the absolute risk Absolute difference in risk between exposed and not exposed
reduction Absolute difference in risk between treated and not treated.
What does validity mean? Accuracy. It is the percentage of all true positives and true negatives
among all the test results
When are relative risk and odds ratios When the incidence of a disease is low, aka when the outcome is
similar? uncommon
4 types of observational bias - Recall - participants with negative outcomes are more likely to
remember exposures
- Observer - observers misclassify the data based on individual
differences in interpretation or preconceived expectations about
the study
- Reporting: Over or under report exposure history because of
stigma
- Surveillance/detection: Risk factor itself causes increased
monitoring in the exposed group → increased chance of
identifying the disease
- Measurement bias: E.g., Hawthorne effect - groups who know
that they’re being monitored act differently than groups who don’t -
remedy is to use placebo
- Procedure bias: Subjects in the two groups aren’t treated the
same
Bias involved in lots of study Selection bias. The control and experimental drop outs may leave for
participants being lost to follow up different reasons (eg. members of one group may be more likely to drop
out because of health problems vs. inconvenience of participating in a
study)
Relationship between PPV and NPV - PPV increases with both prevalence and pretest probability
and - NPV decreases with both prevalence and pretest probability
- prevalence
- pretest probability
Random error and systematic error - Random error reduces precision/reliability, systematic error reduces
which reduces accuracy/validity and accuracy/validity
which reduces precision/reliability?
Crossover study Subjects act as their own controls. E.g., everyone receives a sequence of
different treatments or exposures, all subjects receive the same number of
treatments and participate in the same number of periods.
Standard error of the mean How much variation is there between the sample mean and the true
population mean. SEM = SD/square root of # study participants
Confidence interval Mean +/- (Z * SEM), where Z = 1.96 for 95% CI and 2.58 for 99% CI
Positive skew, negative skew Asymmetry with longer tail on the right, longer tail on the left
ENT
Weber test - different results for the normal, sensineural Normal - no difference
loss, and conductive loss Sensineural - louder in normal ear
Conductive - louder in abnormal ear because this ear
doesn’t hear background noise!
Treatment for abnormal uterine bleeding 1. NSAIDs if ovulatory bleeding. OCPs, mirena
- not heavy 2. Anovulatory → progestins, OCPs, mirena
Endometriosis symptoms cyclical pelvic and/or rectal pain and dyspareunia.OCPs are first line,
also GnRH analogs, danazol, NSAIDs, progestins
Adenomyosis symptoms and treatment noncyclical pain, menorrhagia, and enlarged uterus. NSAIDs are first
line, also OCP or progestins
Features of Noonan syndrome AD. Short, webbed neck, triangle face, delayed puberty, learning
problems
Work up for delayed puberty 1. Start with TSH, bone scan, prolactin
2. Then move to FSH
Age for early puberty - 7 and younger. Most often idiopathic central.
- most common cause - Hypothyroid: bone age is delayed, not advanced
- Sign that it’s hypothyroidism - McCune Albright - period comes first, before hair or breasts
- Sign that it’s McCune Albright
Who gets tested for G&C Anyone < 25 sexually active. Then it’s just risk factors.
Treatment for salpingitis If fever, admit and give IV clindamycin and gentamycin - treat before
cultures returnd
Urinary symptoms with a negative Suspect urethritis - gonorrhea, chlamydia, trichomonas
culture
Who is depo good for? Sickle cell and epilepsy - get fewer episodes
PMS risk factors (vitamins) B6, Ca, Mg deficiency. Treat with vitamins A,B6, E
When to excise breast mass If any red flags on triple assessment: Imaging, biopsy, and physical
exam. A reassuring result on 1 or 2 can’t negate a red flag!
Treatment for endometrial hyperplasia - If no atypia: progesterone - whether oral or UID. Repeat bx in 3-
6 months
- If atypia: generally hysterectomy, but can do progresterone if
want to maintain fertility
Differences between type 1 and type 2 - Type 1: estrogen dependent. Typical endometriod cell, during
endometrial cancer menopause or soon after
- Type 2: papillary serous or clear cell. Estrogen independent.
Atypical patients - late menopause, thin, regular periods
Treatment for endometrial cancer Hysterectomy is first line, but can do progesterone and monitorying for
grade 1 if want to become pregnant
How to manage endometrial polyp Remove if > 1.5 cm because might be malignant
Types of epithelial tumors Serous, mucinous, endometroid, clear cell. Often present late, can have
early GI symptoms.
Miggs syndrome Ovarian fibroadenoma (stromal tumor), associated with ascites and
pleural effusions
Derm conditions - what does the rash - LSC: chronic itching → purple leathery skin
look like? - lichen sclerosis: white. Risk of cancer
- Lichen simplex chronicus - LP: lacy reticulated mucocutaneous rash, usually involves the
- Lichen sclerosis vagina, can obliterate it
- Lichen planus
Granuloma inguinale Small painless nodules in areas of sexual contact → extensive beefy
red ulcers that totally destroys the tissue. Caused by klebsiella
granulomatis.
Causes of bleeding in between periods Endometrial/cervical cancer, uterine polyp, endometrial hyperplasia
- How do progestin containing Both progestin and anti-progestin (ulipristal) delay ovulation.
emergency birth control pills
prevent pregnancy Progestin: 3 days. Ulipristal, more effective, up to 5 days
(levonorgestrel, OCP)?
- How does ulipristal work?
- What is the time frame for use?
Management of endometriosis if strong 1. NSAIDs and OCPs, unless that’s not an option (e.g., desire
suspicion pregnancy) or it doesn’t wor
2. Diagnostic laparoscopy
Obstetrics
Pregnancy milestones - visible sac: 5 weeks
- visible gestational sac - fetal pole: 6 weeks
- visible fetal pole - fetal heart on ultrasound: 6-7 weeks
- fetal heart on ultrasound - earliest hearbeat by doppler: 10-12 weeks
- earliest heartbeat by doppler - fetal movement: 17-18 weeks
- fetal movement
Timing and tests for First trimester screen 9-14 weeks: PAPP-A, beta HCG, nuchal transparency +/- CVS (10-
and Second trimester screen 12 weeks)
15-22 weeks: AFP, beta HCG, estriol, inhibin A, +/- amniocentesis
(15-20 weeks)
- AFP: increased with body wall defects, multiples, placenta
abnormalities. Decreased with trisomy 21 and 18
Duration of labor stages for first time and - First stage is < 4 cm dilation: 6-11 hours vs. 4-8 hrs
multiparous - Second stage is from full dilation: 4-6 hours at 1.2 cm/hr vs.
- First stage - latent labor and active 2-3 hours at 1.5 cm/hr
labor - Third stage: 30 minutes for everyone
- Second stage
- Third stage
Definition of adequate contractions Every 2-3 mins for 40-60 seconds. Or 200 montevideo units in 10
minutes
How often to review fetal heart tracings in - first stage (latent and active): every 30 minutes if no
first stage and second stage for women with complications, every 15 if complications.
complications and no complications - second stage (pushing) 15 minutes if no complications,
every 5 if complications
Definition of early, late, and variable decels - Early: mirror contractions, with onset to nadir > 30 seconds
(gradual)
- Late: onset, nadir, and recovery begin after contraction
onset, peak, and recovery, respectively. Onset to nadir is >
30 seconds (Gradual)
- Variable: Fast drops (< 30 seconds to nadir) that last at least
15 seconds
Nonstress test - reactive and nonreactive - Reactive is > 2 accels of at least 15 bpm (or 10 bpm if < 32
weeks) for at least 15 seconds
- If non-reactive, follow with biophysical profile
Contraction stress test - positive and Positive: late decels after > 50% of contractions in 10 minutes
negative
- Biophysical profile - what does it - BPP - get 2 points for each, 8-10 is normal, 4 or less means
measure? deliver
- What does the modified BPP - Fetal tone (at least one episode of flexion or
measure? extension),
- Breathing - at least one stretch for 30 seconds
- Movement - at least 3
- Amniotic fluid - deepest vertical pocket more than 2
cm or AFI > 5 cm
- non-stress test - reactive
- NST and AFI
What is a normal AFI? > 5 cm → otherwise oligohydromanios and needs further work up.
When to check for gestational diabetes and 50 g BG test: 24-28 weeks, > 140.
what is an abnormal 50 gm response? What Goal fasting BG < 90, 1 hour > 140, 2 hours after meals < 120
is goal fasting and post prandial BG?
HTN in pregnancy - drugs to avoid ACE and diuretics. Both can cause uterus ischemia
Threshhold for HTN in pregnancy and for 140/90, 160/110. Goal is < 160/110 (DBP at least 90-110 to maintain
severe preeclampsia. Goal BP for treatment fetal blood flow)
of severe preeclampsia.
When to give rhogham 28 weeks, after delivery, any exposure to fetal blood
When to give baby steroids? < 34 weeks for steroids. Help with lungs, reduce risk of IV
When to give baby Mg sulfate for brain? hemorrhage, and reduce risk of necrotizing enterocolitis
< 32 weeks for Mg sulfate
Definition of preterm labor and late term 20-37 weeks with contractions and cervical change (> 2 cm and at
labor least 80% effaced), late term is 41-42 weeks, post term is 42+ weeks
Definition of premature rupture of Premature < 1 hr before labor, prolonged > 18 hours
membranes and prolonged rupture
When to use tocolysis Delivery < 34 weeks if no chorioamniotis. It does increase the risk of
chorioamnionitis, so generally done short term
Who gets GBS prophy during labor? Don’t bother testing for GBS (usually done at 35-37 weeks) - just
treat
- GBS positive in that pregnancy, even if treated
- Prior baby with GBS sepsis
Signs of septic thrombophlebitis Picket fence fevers (high spikes then normal) and back/abdominal
pain
When to do elective C section for HIV mom viral load > 1000
Affect of pregnancy on total t4 and t3, free Total hormones increase a lot, because HCG stimulates thyroid
T4 and T3, and TSH hormone production! But at the same time, estrogen increases TBG,
so free T4 and T3 only increase a little. This causes TSH to
decrease
Chorioamnionitis management Give antibiotics, induce labor. Baby will have tachycardia, but that
should come down with antipyretics for mom. Only do a c-section if
the baby has late or variable decels, not based on the tachycardia
alone.
STD screening at first prenatal visit - who to Screen everyone for syphillis, hep B, HIV
screen for G, C, syphilis, HIV, Hep B, Hep G&C: Screen women < 25 and women at increased risk
C? Hep C: increased risk
Time frame for external cephalic version 37 weeks to labor. Make sure the provider is equipped to do an
emergency c section in case something goes wrong
Causes of hyperandrogenism in pregnancy. - Luteoma = yellow SOLID tumors, high risk of virilizing
Features of: female infant. Treatment is just to watch them, they regress
- luteoma after delivery. 50% are bilateral
- krukenberg tumor - Theca lutean cyst = bilateral CYSTS, associated with molar
- theca-lutein cyst pregnancy and multiple gestation. Regress after delivery
- Krukenberg tumor - bilateral ovarian mets from primary GI
cancer
28 weeks pregnant, mom says no fetal Ultrasound! That is the way to confirm an intrauterine fetal demise.
movement. Doppler shows no heart tones. More accurate than doppler. Look for movement and cardiac activity.
Next step?
Abnormal NST - what next? BPP or contraction stress test. If normal, then repeat in 1 week.
Testing for PE in pregnancy Note - d-dimer is always elevated in pregnancy! not useful
Pyelonephritis treatment in pregnancy E coli is most common bug. Treat with IV cephalosporin or amp and
gent
Weird aspects of molar pregnancy Do not biopsy choriocarcinoma - bleeds too much! Diagnose with
beta HCG. Wait 6 months after HCG goes to zero before trying for
pregnancy again.
Criteria for using methotrexate with an not ruptured, < 3.5 cm, beta < 5000, in the tube (not elsewhere), no
ectopic fetal HR, mom will follow up, mom doesn’t have liver problems, etc.
When to place cerclage? Incompetent cervix → 14 weeks (2 weeks into 2nd trimester)
When to do a c section for placenta previa? 34 weeks - once lungs are mature
Risk of isoimmunization if Rh negative mom delivery - 20%. SAB - 2%. Elective 5%.
delivers without rhogham? What about SAB
or elective termination?
Herpes gestationis Very itchy erythematous blisters that begin on the arms and legs and
move to the abdomen. Do immunoflourescent staining of bx -
caused by IgG to basement membrane. Increased risk of still birth
and low growth. Treat with oral steroids.
Management of vasa previa Avoid digital exams, plan for c-section between 35 and 36 weeks to
avoid going into labor at term (contrast previa, which will have a c
section at 34 weeks)
CI for tocolytics - Rotadrine and terubutaline are beta 2 agonists, don’t use
- rotadrine and terbutaline with cardiac arrhythmias or diabetes
- nifedipine - Nifedipine - don’t use in cardiac disease or mix with Mg (risk
- indomethacin of pulmonary edema)
- Indomethacin - avoid > 33 weeks
Management of late term (41 weeks) and 41 weeks: induce with misoprostol if cervix is favorable
post term (42 weeks) pregnancy 42 weeks: induce
Why avoid needle aspiration of ovarian Not curative for benign masses, and risk of spilling cancer cells if
mass malignant
When to deliver in HELLP or preeclampsia > 34 weeks or at any stage if baby or mom is tanking
APGAR Scores A - activity/color - 0 for blue, 1 for pink body but acrocyanosis, 2
for all pink
P - pulse - 0 for none, 1 for below 100, 2 for above 100
G- grimace - 0 for none, 1 for grimace, 2 for sneeze or cough
A for activity - 0 for none, 1 for some flexion, 2 for active
R for respiration - 0 if none, 1 if slow or irregular, 2 if good effort
and crying
What to do for irregular respiration? HR < First two - PPV by bag mask. IF HR < 60, then chest compressions
100? HR < 60?
Okay to ligate these pelvic arteries for Ascending branch of the uterine artery, hypogastric artery = internal
uterine hemorrhage iliac
Management of uterine inversion Place 2 large bore IVs - they are going to bleed (can’t contract). Give
tocolytics (magnesium, terbutaline). Use halothane anesthetic if
really difficult to get back in
Bleeding 10-14 days after delivery subinvolution of the placental site - eschar falls off. Just give
methergine, misoprostol, or prostaglandin F2 to help the uterus
contract
Septic thrombophlebitis Suspect if mom has fevers but otherwise seems fine - eating,
walking, etc. Sometimes see with CT. Treat with short term
anticoagulation and abx
Signs that baby is getting enough milk 3-4 stools in 24 hours, 6 wet diapers per day