GIARDIASIS

ABSTRAK

Teknik untuk sub klasifikasi kelainan familial Giardia duodenalis trophozoites

sudah tercakup secara morfologis perbandingan mobilitas elektroforesis enzim dan

kromosom, dan sekuensing pengkodean gen b-giardin, isomerase triose fosfat, subunit kecil

RNA ribosom dan glutamat dehidrogenase. Saat ini. Giardia organisme duodenalis telah

dikelompokkan menjadi delapan kumpulan genetik (ditunjuk A-H). Genotip dari organisme

Giardia duodenalis yang diisolasi dari berbagai host telah menunjukkan bahwa kumpulan A

dan B menginfeksi rentang terbesar spesies inang, dan tampaknya merupakan kumpulan G.

duodenalis utama (atau mungkin hanya) yang tidak dapat disangkal menginfeksi manusia,

subjek setidaknya pada beberapa kasus infeksi A atau B pada mamalia liar, ada bukti sugestif

bahwa Infeksi akibat pencemaran lingkungan oleh kista Giardia duodenalis berasal dari

manusia.

Kata kunci: Assemblage, Genotype, Giardia, infeksi Giardia, Giardiasis

 GIARDIASIS

ABSTRAK

Techniques for sub-classifying morphologically identical Giardia duodenalis

trophozoites have included comparisons of the electrophoretic mobility of enzymes and of

chromosomes, and sequencing of genes encoding b-giardin, triose phosphate isomerase, the

small subunit of ribosomal RNA and glutamate dehydrogenase. To date, Giardia duodenalis

organisms have been sub-classified into eight genetic assemblages (designated A–H).

Genotyping of Giardia duodenalis organisms isolated from various hosts has shown that

assemblages A and B infect the largest range of host species, and appear to be the main (or

possibly only) G. duodenalis assemblages that undeniably infect human, subjects. In at least

some cases of assemblage A or B infection in wild mammals, there is suggestive evidence

that the infection had resulted from environmental contamination by G. duodenalis cysts of

human origin.

Key words: Assemblage, Genotype, Giardia, Giardia infections, Giardiasis.