“Qrostions 1-6 he soauonce of events during sonamtic tranaminsion at the mcrromuscillar jusetion can be summsrizcd Fhe depolarization produced by an action potential in Uke synaptic terminal opams voltagewdeperdent caleiusn gradients, inducing synaptic vesie'cs filled with acctsicholine CACH} lw fase wilh the plasma membrane Pacing fhemuscle coll. ‘The ACh tz thereby dumped inte the synaptic (eras te cleft #0) te with speatife feceptors on ACh-netivaiedl shanncke When Sodium and potassum som: to eras the membrane. This depolarines the ACh into acetate and chal 10d by the ensyme aevtyloholmesterass At "Saitheerbale of ther seen © Ghthemuncie sur DB in'hewnaptie This suamors that am increase in the amoust of teansin € thedirecean of the wenion pvtontial DD the speed at hicks nerve inpuses tnavat ln fo beleused at the wearomuscubar junction woul protester? Sn hyperpolariration inthe pasteynaptis membrane BA depolarization in the postaynapue membrane The development of am Inhibitory pastsynaptic patents CN ee i a na rere them applica to the mervs termina ty omepporesen Gon fg ymcropipetts ove th feminine pattie ohenind are shown ™ Fig wo ow io oo L—_—__+_—__—_——_(A: CONTROL, mvt EFFECT OF CURARE 7 (@) EFFECT OF ESERINE mv » serine 10° g/m! on © 5 1G 45 20 25 20 Tmecmeecy Ak Acconuing te Pig. L which of the fellowing conchisions was confirried by the experiment? AY Ror fransmiltcr release to Occur, Calciuin fons need only be present after the depolarization of the presynaptic mensbrano The presence of calcium ions is the only variable which affects transmitter releese at the synapse For transmitter release (0 occur, calcium fons "nust be present before and after depolarization of the presynaptic membrane. presynantie membrane cust, calcium ions must be present before cepolarization of the Acsonding to Fig: 3, om sre and eserine could act by. respectively: blocking ion channels and binding te the receptors on. ACh-activated chanmels om channels attd preventing the Iydiaiysis ut acetylcholinesterase. Tu ihic entry of calcium ions inte the synaptic knob and initiating the passage of a nerve impulse alemg the muscle cell. finding to ACh receptor sides on the postsynaptic membrane and preventing. the hydrolysis of acetylcholine a a © D 6. Inthe control of Fig. 2, the part of the curve between 44nd 5 msce represents: AL the absolute rtractory pentod. B. the relative refractory period, © the depolarization of the membrane. D__ saltatory conduction.