Professional Documents
Culture Documents
Now cheaper
One-use-only products
Easy to dye
Applications
Plastics
Medical implants
Drug delivery carriers
Printing and photographic materials
Nutritional supplements.
Effective microbial production of PHA
depends on several factors:
The final cell density.
Bacterial growth rate.
Percentage of PHA in cell dry weight.
Time taken to reach high final cell density
Substrate to product transformation efficiency
Price of substrates
Method to extract and purify the PHA
Ralstonia eutropha + E. Coli
Can grow to over 100 g/l containing over 75% PHA after 100 h of fermentation in a one
cubic metre fermentor vessel
Genetic manipulation, fast growth, high final cell density and
ability to utilize inexpensive carbon sources.
Sources:
E. Bugnicourt, P. Cinelli, A. Lazzeri, V. Alvarez. Polyhydroxyalkanoate (PHA): Review of
synthesis,characteristics, processing and potential applications inpackaging.(2014).
Taken from http://www.iris-eng.com/wp-content/uploads/2016/03/EPL-0005219_article.pdf
Guo-Qiang Chen. A microbial polyhydroxyalkanoates (PHA) based bio- and materials industry
(2009). Taken from https://www.ncbi.nlm.nih.gov/pubmed/19623359