Stratifikasi Antibiotik Perawatan Nonintensif RS tipe B

Spesimen Darah
Gram negatif Klebsiella pneumonia Suseptibilitas AB (%)
E. coli
Lini 1 Amoxicillin 0/31,2
Ampicillin 0/35,3
Ampicillin-Sulbactam 17,1/41,2

Lini 2 Cefotaxime
Ciprofloxacin
Ceftazidime
Aztreonam
Cefepime
Ceftriaxone
Gentamicin
Piperacillin-tazobactam
Trimethoprim-sulfametoxazole

Lini 3 Amikacin 97,1/100

Ertapenem 48,6/100
Meropenem 48,6/100
Tigecycline 94,3/100
 Spesimen Darah
Gram positif Staphylococcus epidermidis Suseptibilitas AB (%)
Staphylococcus hominis
Staphylococcus haemolyticus
Lini 1 Amoxicillin-clavulanic acid
Ampicillin-Sulbactam
Cefepime
Cefoperazone
Cefotaxime
Ceftazidime
Ceftriaxone
Clindamycin
Erythromycin
Oxacillin
Penicillin
Ticarcillin- clavulanic acid
Piperacillin-tazobactam

Lini 2 Gentamicin
Ciprofloxacin
Levofloxacin
Moxifloxacin?
Trimethoprim-sulfametoxazole
Tetracycline

Imipenem 20/0/33,3
Lini 3 Linezolid 100/100/100
Tigecycline 100/100/100
Vancomycin 88,9/100/100
Rifampin 75/69,2/80

Doripenem 20/0/33,3
Meropenem 20/0/33,3
 Spesimen Sputum
Gram negative Klebsiella pneumonia Suseptibilitas AB (%)
Pseudomonas aeruginosa
Acinetobacter baumannii
E. coli
Lini 1 Ampicillin
CZO

Lini 2 Ampicillin-Sulbactam
Aztreonam
Cefepime
Cefotaxime
Ceftazidime
Ceftriaxone
Ciprofloxacin
Gentamicin
Piperacillin-tazobactam

Lini 3 Amikacin 97,5/75,7/63,5/100

Ertapenem 95,8/-/-/92,3
Meropenem 95/56,8/52,4/92,3
Tigecycline 93,3/0/63,5/100
 Spesimen Sputum
Gram positif Staphylococcus aureus Suseptibilitas AB (%)
Streptococcus pneumoniae
Staphylococcus epidermidis
Lini 1 Ampicillin

Lini 2 Amoxicillin-clavulanic acid

Ampicillin-Sulbactam
Cefepime
Cefoperazone
Cefotaxime
Ceftazidime
Ceftriaxone
Cefuroxime oral
Ciprofloxacin
Clarithromycin
Clindamycin
Doxycycline
Erythromycin
Levofloxacin
Moxifloxacin
Piperacillin-tazobactam
Ticarcillin-clavulanic acid
Oxacillin
Penicillin

Lini 3 Amikacin 100/-/-

Gentamicin 88,9/-/92,3
Imipenem 91,4/-/25
Linezolid 97,1/100/100
Rifampin 97,1/-/69,2
Tigecycline 100/-/100
Trimethoprim-sulfametoxazole 97,1/100/69,2
Vancomycin 97,2/100/100
Doripenem 91,4/-/25
Meropenem 91,7/-/25
 Spesimen Urine
Gram negative E. coli Suseptibilitas AB (%)
Klebsiella pneumonia
Lini 1 Amoxicillin
Ampicillin

Lini 2 Ampicillin-Sulbactam
Aztreonam
Cefepime
Ceftazidime
Ceftriaxone
Ciprofloxacin
Gentamicin
Trimethoprim-sulfametoxazole

Lini 3 Amikacin 100/100

Ertapenem 100/90
Meropenem 97/90
Nitazoxanide 97/40
Piperacillin-tazobactam 90,9/50
Tigecycline 100/90

Spesimen Pus
Gram negative E. coli Suseptibilitas AB (%)
Klebsiella pneumonia
Lini 1 Ampicillin

Lini 2 Ampicillin-sulbactam
Aztreonam
Cefepime
Ceftazidime
Ceftriaxone
Ciprofloxacin
Gentamicin
Piperacillin-tazobactam
Trimethoprim-sulfametoxazole

Lini 3 Amikacin 100/100

Meropenem 100/86,7
Ertapenem 100/83,3
Tigecycline 100/69,2
 Spesimen Pus
Gram positif Staphylococcus aureus Suseptibilitas AB (%)
Lini 1 Tetracycline

Lini 2 Ciprofloxacin
Clindamycin
Gentamicin
Levofloxacin
Moxifloxacin
Oxacillin
Trimethoprim-sulfametoxazole

Lini 3 Linezolid 100

Tigecycline 100
Rifampin 90
Vancomycin 95
Erythromycin 95
Stratifikasi Antibiotik Perawatan Intensif RS tipe B

Spesimen Darah
Gram negative Klebsiella pneumonia Suseptibilitas AB (%)
Lini 1 Ampicillin-Sulbactam
Piperacillin-tazobactam
Trimethoprim-sulfametoxazole

Lini 2 Gentamicin

Lini 3 Amikacin 100

Ertapenem 92,3
Meropenem 92,3
Tigecycline 92,3

Spesimen Darah
Gram positif Staphylococcus hominis Suseptibilitas AB (%)
Staphylococcus haemolyticus
Lini 1 Cefotaxime
Clindamycin
Erythromycin
Penicillin

Lini 2 Gentamicin 93,3/60

Ciprofloxacin
Levofloxacin
Moxifloxacin
Tetracycline
Trimethoprim-sulfametoxazole

Lini 3 Linezolid 93,3/80

Tigecycline 100/100
Vancomycin 86,7/80
Rifampin 86,7/60
 Spesimen Sputum
Gram negative Pseudomonas aeruginosa Suseptibilitas AB (%)
Acinetobacter baumannii
Klebsiella pneumonia
Lini 1 Ampicilin sulbactam
CZO
Ceftriaxone
Lini 2 Cefepime
Cefotaxime
Ceftazidime
Ciprofloxacin
Gentamycin
Trimethoprim-sulfametoxazole
Lini 3 Ertapenem -/-/91,8
Amikacin 57,9/56,8/93,9
Meropenem 43,9/29,5/91,8
Tigecycline 0/37,2/91,8

Spesimen Sputum
Gram positif Staphylococcus epidermidis Suseptibilitas AB (%)
Streptococcus pneumoniae
Staphylococcus aureus
Lini 1 Penicilin

Lini 2 Amoxicilin-Clavulanic Acid 89,5/-

Ampicillin-Sulbactam 89,5/-
Cefoperazone 89,5/-
Ceftazidime 89,5/-
Cefuroxime 89,5/-
Ciprofloxacin
Clindamycin
Erythromycin
Levofloxacin
Moxifloxacin
Oxacillin

Lini 3 Cefepime 89,5/-

Gentamicin 90,5/-
Imipenem 89,5/-
Trimethoprim-sulfametoxazole 90,5/-
Ticarcillin-Clavulanic Acid 89,5/-
Ceftriaxone 89,9/100
Cefotaxime 85/100
Linezolid 100/100
Doripenem 89,5/-
Vancomycin 100/100
Tigecycline 100/-
Imipenem 89,5/-
Rifampin 95,2/-
Piperacillin-tazobactam 89,5/-
Meropenem 89,5/-