Maternal and Perinatal Outcomes of Gestational Diabetes Mellitus in

Persahabatan General Hospital

Yuyun Lisnawati, Devi Marischa Malik, Kindy Agustin Wati, Nadia Nurfauziah

Department of Obstetrics and Gynecology

Persahabatan General Hospital

ABSTRACT

Background: The prevalence of gestational diabetes mellitus increases along with the high
prevalence of diabetes mellitus type 2 in the world. Early identification of gestational diabetes
mellitus is important for maternal morbidity and perinatal outcomes. The objectives of this
study is to determine the maternal and perinatal outcomes of gestational diabetes mellitus and
investigate association among GDM maternal fasting glucose test and HbA1c with
preeclampsia, preterm labor, and macrosomia in Persahabatan General Hospital.

Methods: This was a cohort-retrospective study with subject population were all patients who
had gestational diabetes mellitus and had treatments in Persahabatan General Hospital from
January 1, 2013 to December 31, 2016 . The study included 75 GDM patients who diagnosed
by fasting glucose test, oral glucose test, or hba1c. Exclusion criteria were patients who
dropped out of treatments and had labor in another hospital. The data was collected by using
medical records . The Chi-Square test was used to do bivariate analysis. The Fisher test used if
the criteria for Chi-Square test was not fulfilled. Statistical significancy data was analyzed by
using SPSS v.20.

Results: The incidence of GDM in the population studied was 3.26%. Pre-eclampsia
complicating pregnancy was noted in 6.7% patients, preterm labor in 4% patients,
macrosomia in 16%, and HbA1c >6.5 in 40.4% patients. The significant association
was showed by fasting glucose level of GDM patients and macrosomia in perinatal
outcome (p=0.001). HbaA1c level of GDM patients was also significantly associated
with macrosomia (p=0.05).

Conclusion:
GDM was significatly associated with macrosomia in perinatal outcome in terms of maternal
fasting glucose level and HbA1c during pregnancy.

Keywords : gestational, diabetes mellitus, maternal, perinatal, outcomes, .