‘ovelhas na qual o gene humano para o fator
1X foi nserido como um promotor que
‘a expressio da transgénese na glandula
sa (Schnicke et al., 1997). Com este evento
© conceito de “biofirmacos" (producto de
‘valiosas na transgénese animal). O relato
foi precedido por outro do grupo de Rolin;
jcagao que surpreendeu ndo somente a
fe cientifica, mas todas as leis da socie
‘mundial: a noticia do nascimento da ovelha
Dolly (Wilmut etal, 1997). Dolly foi criada
we seu grupo por transferéncia de células
dda glandula mamaria de uma ovelha de
de idade em dvulos enucleados. Novamente,
dependeu do controle do ciclo celular,
doadoras nucleares da glandula maméria
‘mantidas em cultivo, 0 que suprimiu sua
mitotica, provocando um estado de senes-
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