ve edevrdar} Date: June 28", 2002 | 130 Agenda 3 1) Review Analysis Plan a. Update Power Calculations i. Birth Certificate Sample 1. Original Controls with Birth Certificate N=1049 2. Matched Controls with Birth Certifc ii, Subgroup Analyses T, Matched Analyses 2. Unmatched Analyses 2) Review Data Issues a Sample Selection ~ See Table b. Descriptive Data for Cases - Table 2 i, Subgroups ii, Dropped epilepsy from table 3) Preliminary Results a. Table 4 — Primary Analyses b. Table 5 — Unmatched Subgroup Analyses 4) Creation of Public Use Data Set a. Data privaey Issues i. NCHS Model t ii, OthérModel b. Code Book c. SAS ve )‘S9”000Y 002 Sample Selection for MMR/Autism Study Controls Cases Selection Criteria Yes No No% Yes No No% Available Sample 2143 706 Valid CASENUM 2113 30 1% 706 0 0% Confirmed Autism Case 2113 0 0% 660 46 7% Matched Cases and Controls 1912 201 10% 647 43 2% Original 3 Controls 1891 a 1% 647 0 0% Missing Age Data 1890 1 0% 647 ° 0% Missing MMR Vaccine Date (1,2) 1876 14 1% 629 18 3% 1) 11 controls were missing their entire vaccination record 2) 14 cases were missing their entire vaccination record6/28/2002 Table 1: Descriptive Statistics For Entire Sample * Variable Category comicts coe N___Porcent___N__Percent. ‘Age 1996 3-5yrs 635 34% 215 34% 6-8yrs, 973 52% 321 51% 9-10 yrs 268 14% 93 18% Total 1876 100% 628 100% Sex Male 1508 80% 505 80% Female 370 20% 124 20% Total 1876 100% 629 100% Race White 930 52% 336 55% Black 674 38% 232 -38% Other 175. 10% 40 1% Total 479. 100% 608 100% * All subjects reported in table had date of receipt of MMR vaccine * All cases are confirmed cases. (4000466