Tatalaksana Perdarahan

Tatalaksana Perdarahan pada Infeksi dengue:

• Pencegahan
• Deteksi Dini
• Pemberian Tranfusi
Mengapa terjadi perdarahan ???
 Dengue Virus Infection

Bleeding (hemorrhage)
• Petechie, purpura, ekhimosis
• Epithaxis , massive bleeding
• DIC
A: hemorrhage of the great
epiploon and hemorrhage in the
serous of the INTESTINAL
TRACT

B: LIVER –hepatic congestion

(arrow) on the liver surface
covered by sharp exudate as a
result of perforation into
duodenal ulceration (arrow).

C and D: HEART. hemorrhagic

(arrow) fibrin pericarditis.

E: LUNG – hemorrhagic (arrow)

sulphution
of the visceral pleura.

F: SPLEEN – splenic congestion

and hemorrhagic (arrows)
capsular focus.
Lei/Yeh/Liu/Lin/Chen/LiuJ Biomed Sci 2001;8:377–388
Platelet disorder Dengue Virus Infection
-Thrombocytopenia
- Platelet Aggregation
Liver disfunction

Hemostatic abnormality
Disturb Vascular Integrity
(coagulation vs fibrinolysis)

Bleeding (hemorrhage)
• Petechie, purpura, ekhimosis
• Epithaxis , massive bleeding
• DIC
Tranfusi trombosit
Apa yang menjadi penyebab terjadinya perdarahan ???

Duration of Shock were risk factors of severe hemorrhage

OR, 2.11, 95%CI, 1,13 to 3,92. P = 0.19
Platelet disorder Dengue Virus Infection
-Thrombocytopenia HIPOPERFUSI
- Platelet Aggregation
Liver disfunction
HIPOKSIA

Hemostatic abnormality
Disturb Vascular Integrity
(coagulation vs fibrinolysis)

Bleeding (hemorrhage)
• Petechie, purpura, ekhimosis
• Epithaxis , massive bleeding
• DIC
Cegah hipoperfusi = cegah perdarahan
Tranfusi darah segar
Tranfusi darah segar
PENTING…..!!!!
TIDAK ADA TRANFUSI PROFILAKSIS