CREATININE (ENZYMATIC) Package nso instrucions mus be costly tole, Reb of assay rsuls cannot be gusrartod thos ae ay deviations Hom the Instucters mths package rer ead Hahlted Chonaes; Revised Mich 2017, INTENDED USE ‘The MULTIGENT Crextnine (Eraynate) asay is intended fr he ‘uantatve determination of sreatnine human serum plasma, and thin using the ARCHITECT cSyzoms. ‘SUMMARY AND EXPLANATION OF TEST Creatine i lmnated rom boos By omens fivaon. Recueod ‘ena ureten eeu in an inseased sen crosinine concen, Massuremor of serum crstne is sed fo diagnose ars monsor note and chore renal seas, ema gomeuar iraton rate (GF), 0° {Seeoee tho dats cf orl dalyis patents sno reat anaes Is used to cacuae creatine deze, confirm completes of 2esnour easton, env ae aceon quay fr ster anaes, uch et in ealelton of te aburinjcroainno ata" PRINCIPLES OF PROCEDURE Grainne inne sence tyes by cease to caine: {retin stra ye by erat to soni 2 ra Sacoona nm th wanton ned by sacar oar to ahyohe ‘nd lomgleny, wh te enaaet ston of Sysone roms Tho open pode reas wth «aminarpyne ad EGSha ine posonn of porocante told a qunonortine dy. “hares change in abserbanos st 5 nm proportorl oo cece cancataaion nthe seme. Ths enact i Sess and spots or ese anid no fern Oy endogenous Subsarse such an eau cophaspotna on nha Pak ‘etow ath the ate neo ESPIT = Neth sory ohicina ‘Beet crete REAGENTS Reagent Kit MALTICENT Creatine (Enamrate pled 25 abu ead. ‘ownage woh eons Baas excam. ante aL Esra os port 70" Ban {] 10x90m. fe bxsem. simatd ices por Kt 4.820" * Caleta is Exsed on te isimar reagent il vue por kt Faacie rears Careers TA] Good's stor 7) 25 mol, Creatinase 212 kuL Strossine xis eK Catalase = 200 KUL SPT. 0.47 mmol “Ba Good's Sater wT 00 roi Creatininase 500 KYL Peroridase 220 KUL scamncantoyrne 205 mmol, roast Ingroires: [i coniins detergrt (<1) and presente [Bel corns etergont (= O58) and sesum azie (<0). REAGENT HANDLING AND STORAGE Reagent Handling [Ba] oasy tor uso. + Tl Ready tor use + Bemove i bubties poser inthe reegant carnage win @ new sppleator etek. Aternably alow ie reagent stot he _2propiate storage ianpuau to alow te bblest espa “oimnimaze vaume dplen, do nol ube Yarstar ppt To rmnove the bubbies ‘CAUTION: Feaget bubble may nteriere with proper detecion of feagurt level inno eaispa, causing moult agent sepraton ‘hat cau mpact veut & en (CREATININE (ENZYMATIC) }8L24-31 and 8124-41 G10667/RO8 B8L240 ARCHITECT Reagent Storage * Unopened regents ae stable ut the exaton date when sort R208. + agent Sabiy i 80 dye # he reagontie uncapped ane onboard Indications of Deterioration ‘The regent must be clos eabily er doerirtien shou be i theo aro wll sigs of fakage, tural mera growth fri ealbaion exes nt moot he apropate package Isat anal [ARCHITECT Syetom Operations Manal teria. NOTE: sign ytow coloration wl ot tle reapee pavermanoa WARNINGS AND PRECAUTIONS Precautions for Users + For Vso Diagestic Use + De not uso components boyoné tho oxation de + Bo net ma area Creme x ruber + CAUTION: Te product rqures ie hencng 9 human specimens, W's resonmendes that al furan soured rte be conscered potest locious and handles in aczardanoa mh the OSHA Standard on Sodborre Pathogens“ Basalety Love! 2° oF ober sppoprat iat pasion’ shoul bo used for materia tha orn o ate suspected of conaring inectous agents “Te fofowng warring and proautone apply 2} Conisne sain 222, oe EUHOS2 Contact wit ais borates very tx so? Depa af eomriseomsnr i secodance wt al po nn ee nn - ESR lees eg te ct cn pc ‘SPECIMEN COLLECTION AND HANDLING ‘Suitable Specimens * Serum: Use serum coated by standard venipuncture tecmniques ino labo tubes wih or witcat gel baer, Enaur corte ot ormation has taken lace porto cnttgation. Conte {ccordrg to ube manulacurer's nsructons to ensue pepe” Seperaton of serum trom bse cas Glas tubes were not tests. ‘Sem specinens, especial tooo om patos recokrg srtccagurt or ‘erapy may take ergo o completo ‘hake cating procosees Pinte nay seen Som ne + Plasma: Use plasma collected by andar veipuncure‘ecbiques| ‘no paste tubes, Te aboostadleartcoaguars are hum hapa {jo winour gol Bern and Sodium hath, EDTA ena ‘ecormonded. An trl st) showed deroasod este ERG ‘entfugation is adequsto to romove pte. Corauge aooorcing to lube manutecturr'sfaractone fo ensure proper separation of ‘Siam from boos col Glass tes wero not ee, + Wine: Colect untied specimens or specimens timed ovr intra ‘horer han 24 hers wih no pesoraive + 2éHour Urine: May be oaootos wih preservative. The prefered ‘resonates oe bore aot and hycrochiorc aed.*Relernce ranges ‘re promod fo 24-hour sxreton. NTE: Urine epecinons mus bo inepeta fr parfouts. I proce, Cenrfag the spectron to romovopariculaes prt testing For ttl ease vue raguvorent, oe othe ASSAY PERAMETERS ‘soot ofthis package eer and Secon 5 of the ARCHITECT System ‘Operations Manual