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Department of Pathology, End semester test. JIPMER KARAIKAL 17.06.19.

TIME- 9am to 10.30am Total marks - 40

Answer in Detail: (10marks)


A 54 yr Male presented with dragging sensation in the abdomen ,loss of appetite and loss of weight for
the past 6 months.O/E ,Pallor +,Spleen was moderately enlarged.His blood examination reveals,Hb-
8.5gm%,TC-1,65,000 cells/cu.mm,Platelets-1,02,000 cells/cu.mm.
1.Write the etiopathogenesis of this condition.
2.Mention the three phases of this condition.
3.Discuss the role of lab investigations in the prognosis of this disease.

Write short notes on: (4marks)

1. Laboratory workup of a 9 yr old boy with haemarthrosis.


2. Lab investigations of irondeficiency anemia.
3. Write about Leukemoid reaction and its types.
4. Write about Coombs test and its types with proper examples.
5. Role of cytogenetics in acute Leukemia.

Write Brief Answers: (2marks)

1. Write two differences between lymphoblast and myeloblast.


2. Write about the two types of crossmatching.
3. Write the characteristic peripheral smear finding and bonemarrow change in chronic
ITP.(Idiopathic thrombocytopenic purpure)
4. Mention the types of Hodgkins lymphoma.Draw a classic Reed-sternburg cell.
Two laboratory investigations for Sickle cell anemia.

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