Characterizations of bacteria isolated from uroliths

and urine in canines attending

Khon Kaen animal hospital

Rationale
An urolith may be defined as the aggregation of crystalline
and matrix materials that form in one or more locations within
the urinary tract when urine becomes oversaturated with
crystallogenic substances, and may be composed of one or
more mineral types. Uroliths that form in cats, dogs and
humans can be grouped into four main mineral types, namely
urate (including ammonium urate, sodium urate and uric acid),
cystine, calcium ( calcium oxalate and calcium phosphate) and
magnesium ammonium phosphate (struvite stone).
Urolithiasis is a recurrent clinical problem in dogs
throughout the world. The prevalence of urolithiasis in dogs
was reported to be between approximately 0. 25 and 0. 5% in
Sweden and Norway, 3% in Ukraine, 0.5% in North American
veterinary colleges and in European countries such as Germany
with an estimated incidence of 0.5–1%.
Specific types of uroliths have been associated with
bacterial urinary tract infections (UTIs), particularly struvite
stone, in which the most common microbe found is urea
splitting bacterium. Uroliths can also act as a nidus for infection
and can be found in dogs with recurrent UTI. It has been
reported that bacteria isolated from the urine may differ from
what is found in the urolith; therefore, cultures of uroliths are
warranted. In human beings, positive urolith cultures are better
predictors of potential urosepsis compared to urine collected
from the bladder. However, our observation indicated that it
might not be the case of uroliths in Thailand. We therefore
extensively characterized microorganisms isolated from uroliths
and urine of canines attending Animal Hospital Faculty of
Veterinary Medicine Khon Kaen University.

Objective
To characterize of bacteria isolated from uroliths and urine
in canines attending Animal Hospital Faculty of Veterinary
Medicine Khon Kaen University.