Hyaluronic Acid (Hyaluronic Acid, Sodium Hyaluronate, HA) has many benefits and is one of the most

interesting ingredients in skin care, specifically. Naturally found in the body, hyaluronic acid secures
moisture and creates fullness—youthful skin naturally abounds with hyaluronic acid.

Hyaluronate sodium is used for: Treating knee pain in patients with osteoarthritis who have not received
relief from other treatments. Hyaluronate sodium is a hyaluronic acid derivative. It works by increasing
the effectiveness of the fluid within the knee joint to act as a lubricant and shock absorber.

Possible side effects of hyaluronate sodium:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your
doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; mild bruising, redness, or pain at the injection site; mild stiffness, swelling, warmth, or pain in
or around the injected knee; muscle or joint pain; temporary achy feeling.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the
mouth, face, lips, or tongue); severe or persistent headache or dizziness; severe, persistent, or painful
swelling of the injected joint.

This is not a complete list of all side effects that may occur. If you have questions about side effects,
contact your health care provider. Call your doctor for medical advice about side effects. To report side
effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.