Mohit Kumar, Shweta Jaiswal, Kushneet Kaur Sodhi, Pallee Shree, Dileep Kumar Singh,

Pawan Kumar Agrawal, Pratyoosh Shukla,

Antibiotics bioremediation: Perspectives on its ecotoxicity and resistance,
Environment International,
Volume 124,
2019,
Pages 448-461,
ISSN 0160-4120,
https://doi.org/10.1016/j.envint.2018.12.065.
(http://www.sciencedirect.com/science/article/pii/S016041201832381X)
Abstract: Antibiotic is one of the most significant discoveries and have brought a
revolution in the field of medicine for human therapy. In addition to the medical
uses, antibiotics have broad applications in agriculture and animal husbandry. In
developing nations, antibiotics use have helped to increase the life expectancy by
lowering the deaths due to bacterial infections, but the risks associated with
antibiotics pollution is largely affecting people. Since antibiotics are released
partially degraded and undegraded into environment creating antibiotic pollution,
and its bioremediation is a challenging task. In the present review, we have
discussed the primary antibiotic sources like hospitals, dairy, and agriculture
causing antibiotic pollution and their innovative detection methods. The strong
commitment towards the resistance prevention and participation, nations through
strict policies and their implementations now come to fight against the antibiotic
resistance under WHO. The review also deciphers the bacterial evolution based
strategies to overcome the effects of antibiotics, so the antibiotic degradation
and elimination from the environment and its health benefits. The present review
focuses on the environmental sources of antibiotics, it's possible degradation
mechanisms, health effects, and bacterial antibiotics resistance mechanisms.
Keywords: Antibiotics; Bioremediation; Biofilm; Microbial consortium; Degradation