OUR PATIENT AN a 29-Year old female, admitted (3/13/19), with Dx of ABW: 127 lbs. (57.7 kg) DAY 01 Ht: 62 in. (157.48 cm) Rectal CA 20 week IUP, s/p low anterior resection (LAR) with BMI: 23.32 (Normal) IBW: 110 lbs. Total mescorectal excision (TME). Weight Hx: Operative report 112 lbs. (3/13), admit wt. 127 lbs. (3/14), bed wt. 136 lbs. (3/15). FOOD NUTRITION HX Diet: CLLQ (3/14), FULQ (3/15), Reports being on a special diet for colitis prior to Sx procedure. PO intake: Per nurse <25% (3/14-3/15) GI: N/V Per Pt. PMHX Estimated needs: Based on Admit wt. GERD, H.Pylori, Colon Cancer, Rectal Bleeding, Chlamydia, Anemia, Calorie: 2,040 kcal/day (30 kcal/kg + 300 kcal for pregnancy) Ovarian Cyst, Alcohol Abuse, Tobacco Use, Substance Abuse. Protein: 112 gram/day (1.5 g/kg + 25 for pregnancy) HOSPITAL COURSE Fluid: 2,325ml/day (30 ml/kg + 600 ml for additional loss from colostomy) 3/4/19: Biopsy confirmed Colonic Adenocarcinoma 3/13/19: Partial colectomy end colostomy transferred to PACU 3/15/19: FULQ 3 bouts of emesis from ensure, Nausea 3/17-18/19: NPO Post op Ileus (3/17) 3/19-20/19: CLLQ, started TPN (3/19 @ 17:00) 3/21/19: TPN DC at 09:20, Soft diet-Regular. Some hard stool passed. OB consult for viability. Pt. Discharged on Regular diet. PROCEDURES RELATED TO ADMISSION DIAGNOSIS 3/13/19: Low anterior resection, w/ total mesorectal excision resection of paraaortic and paracaval nodes. 3/19/19: PICC placement SVC w/ Chest Xray- Expanded Lungs PATHOPHYSIOLOGY OF RECTAL CANCER Colonic Adenocarcinoma- the most common type of colon cancer starts in goblet cells that form glands producing mucus for lubrication of colon and rectum. Cancer of the colon most commonly begins with adenomatous polyps, which are noncancerous (benign) clumps of cells. Polyps are caused by mutations in certain genes causing continual division of cells. Hereditary conditions that cause colon polyps to form include Lynch syndrome, Familial adenomatous polyposis, Gardner’s syndrome, MYH-associated polyposis, Peutz-Jeghers syndrome, and Serrated polyposis syndrome. Signs and symptoms- include rectal bleeding, change in stool color and change in bowel habits, pain, and iron deficiency anemia. DIAGNOSIS PATHOPHYSIOLOGY OF TOTAL COLECTOMY W/ COLOSTOMY (3/15) Altered GI Function R/T Colon carcinoma AEB colostomy, vomiting, Total colectomy- is a surgical procedure to remove the large and no colostomy output. intestine from the distal ileum to the rectum. LAR is a surgery (3/19) Inadequate oral intake R/T limited food acceptance AEB vomiting done to treat cancer of the rectum. Part of the rectum is removed and nausea and intake less than 10% x 10 recordings. and the remaining part of the rectum is reconnected to the colon. (3/21) Excessive parenteral nutrition infusion R/T increased total volume This is called an anastomosis. TME strictly applies in the TPN w/ dextrose @ 15% still AEB carbohydrate consistently more than performance of a LAR for tumors of the middle and lower rectum. recommended intake. Colostomy- (ileostomy) is needed for a short time after LAR. A INTERVENTION colostomy keeps waste from passing through the colon and Recommendation: (3/15-3/19) Cont. FULQ diet with ensure TID and advance rectum allowing the anastomosis to heal. A part of the small as tolerated to Low residue bland diet. intestine is brought out through an opening made in the Discussed current FULQ diet and delivered handout for colostomy nutrition. abdomen called a stoma. A waterproof pouch (colostomy bag) is (3/19) TPN- @ 85 ml/hr D15% 110gAA 60Lipid to meet pt. nutrition needs. used to collect waste from the body. (3/21) TPN- @ 95 ml/hr D13% 110gAA 60gLipid to meet pt. nutrition needs. Nutrition therapy- Focus on decreasing risk of obstruction, (2047 kcal) Continue soft diet and monitor PO intake. maintain fluid and electrolyte balance, reduce excessive fecal MONITOR AND EVALUATION output and/or change consistency of output, and minimize gas. Monitor: (3/15) PO intake, Wt., Diet Tolerance PREGNANCY Goal: PO >75%, Stable Wt., Advance to solid foods. Normal weight gain for pregnancy is 25-35 lbs. if the patient is of Monitor: (3/19) Labs, wt., Blood glucose, GI Function, PO intake normal BMI. For the second and third term women need an extra Goal: PO >75%, Stable Wt., Advance to solid foods. 300-450 kcal/day to support fetal needs. Protein needs are Monitor: (3/21) Labs, wt., Blood glucose, GI Function, PO intake, PN-related estimated to be between 75-100 grams, an additional 25 grams is complications considered for lactation. This was applied to AN due to increased Goal: Stable wt., Stable labs, Continue with TPN until PO intake average is > 75% for needs from surgery and previous weight loss during pregnancy. a minimum 3 days, BM or colostomy output. Both total red blood cell mass and plasma volume increase, but NUTRITION RISK: SEVERE plasma volume increases to a greater extent resulting in hemodilution and anemia during pregnancy. Anemia during second trimester is defined by an Hgb <10.5 g/dL and an Hct <32%.. Serum total protein and albumin decrease by 30% during pregnancy. The RDA of micro nutrients increase, specifically vitamin A, and D, folate, niacin, riboflavin, thiamin, pyridoxine, cobalamin, vitamin C, iron, selenium, and zinc. RFERENCES
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942743/ Kominiarek M, Rajan P. (2016). Nutrition recommendations in Pregnancy and lactation. Med Clin North Am. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104202/ Nelms M, Sucher K, Lacey K. (2015). Nutrition Therapy and Pathophysiology. Boston, MA. Cengage learning. Dahling M, Gubo X, Cress R, Danielsen B, Smith L (2009). Pregnancy-associated colon and rectal cancer: perinatal and cancer outcomes. Journal of maternal-Fetal and Neonatal Medicine (23) 204-211. doi: 10.1080/14767050802559111 The Royal College of Obstetricians and Gynaecologists. https://www.rcog.org.uk/globalassets/documents/guidelines/green-top-guidelines/gtg69- hyperemesis.pdf. June 2016.
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