CHAPTER 44. Tetracyclines, Macrolides,Clindamyein, Chloramphenicol, Streptogramins, & Oxazolidinones 797
SUMMARY Tetracyclines, Macrolides, Clindamycin, Chloramphenicol,
eRe tects Ered
Erne
+ Teragtine reventsbacer poten | sacercstatcactny | Infecens eased by famed learanc hale 8) = dosed
‘sytessby binding tore| against sxcepible | mycoplasma chamydne, | every 6h -daent ators maior
“Sita subunit | bce ‘heft, seme sprocete- | absorption Tx Gastonia pet,
Imalia-Hpni-acne | Pepatotonicy, phototenstvty, postion mn
tne ond teeth
+ Dosjcyine Osan longer hale 18 ode ne dey; nena ehinaton: absorptions minal ected duce ation sed eat community
‘cquiedpoeumonia nd acerttanc al bondi
+ Miocyie Oa onger hal ie (16. so dosed ce daly equ couse reverb eet
| Teed Vana by common ety msstance mechani; wey bad petra fact against gampastive gmnetne and anerbi btn:
autea and venting are th primary ties
MACROUDES
+ Emtomycin Preventsbactael prota | Bactaostaicactivty | Communitpacauted Ora Wshapatc erence fall 15)+
yntedsty binding tone | again susceptible | preumona peruse | doredevery 6h -cjoehome PASO inhibar =
S0Srboiomalsubune | bacteria ‘onnebacteral and Tasty: Gastolestnal upset hepato,
ham ifetions (OF, prlengation
+ Centro Oa ange hal (6h so dosed ke daly addedactty aus M avium complex toplesa, and Meas
+ Aaoryei: Or vlog hal fe 68 halons once daly desing and dy couse of tharpyocommany-auedprewrni does etn yochome
Pasdenzymes
+ Teltramyc: Oat uae by elit medted stance os active versus many etromycn estan sas of prewnococc ae cass of fuminant hepa axe
LUNCOSAMIDE
+ linda Preventsbacedelprotin | aactestticactinty | Skinand wt sue Ora Ws patie cera ale?)
‘ptteastytinding tome | agains wicepible” | intent aerobic doses evry 6-8 hours Tow
‘S0Sribowmalsubunt | baer Infections Gastintetinal pet iele cls
STREPTOGRAMINS
+ Quinupsin- Provetsbacealprotin | Rapidbactaial | Infeconseausedby 1 hepatic cerance dosed every #-12h-