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CHAPTER 44. Tetracyclines, Macrolides,Clindamyein, Chloramphenicol, Streptogramins, & Oxazolidinones 797 SUMMARY Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, eRe tects Ered Erne + Teragtine reventsbacer poten | sacercstatcactny | Infecens eased by famed learanc hale 8) = dosed ‘sytessby binding tore| against sxcepible | mycoplasma chamydne, | every 6h -daent ators maior “Sita subunit | bce ‘heft, seme sprocete- | absorption Tx Gastonia pet, Imalia-Hpni-acne | Pepatotonicy, phototenstvty, postion mn tne ond teeth + Dosjcyine Osan longer hale 18 ode ne dey; nena ehinaton: absorptions minal ected duce ation sed eat community ‘cquiedpoeumonia nd acerttanc al bondi + Miocyie Oa onger hal ie (16. so dosed ce daly equ couse reverb eet | Teed Vana by common ety msstance mechani; wey bad petra fact against gampastive gmnetne and anerbi btn: autea and venting are th primary ties MACROUDES + Emtomycin Preventsbactael prota | Bactaostaicactivty | Communitpacauted Ora Wshapatc erence fall 15)+ yntedsty binding tone | again susceptible | preumona peruse | doredevery 6h -cjoehome PASO inhibar = S0Srboiomalsubune | bacteria ‘onnebacteral and Tasty: Gastolestnal upset hepato, ham ifetions (OF, prlengation + Centro Oa ange hal (6h so dosed ke daly addedactty aus M avium complex toplesa, and Meas + Aaoryei: Or vlog hal fe 68 halons once daly desing and dy couse of tharpyocommany-auedprewrni does etn yochome Pasdenzymes + Teltramyc: Oat uae by elit medted stance os active versus many etromycn estan sas of prewnococc ae cass of fuminant hepa axe LUNCOSAMIDE + linda Preventsbacedelprotin | aactestticactinty | Skinand wt sue Ora Ws patie cera ale?) ‘ptteastytinding tome | agains wicepible” | intent aerobic doses evry 6-8 hours Tow ‘S0Sribowmalsubunt | baer Infections Gastintetinal pet iele cls STREPTOGRAMINS + Quinupsin- Provetsbacealprotin | Rapidbactaial | Infeconseausedby 1 hepatic cerance dosed every #-12h-

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