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19
Veterinary Clinical Medicine, Ethics and describes renal damage due to primary
jurisprudence cardiovascular diseases and their management.
Although the prevalence of CvRDH is
4(a). Name of the major advisor (Guide)
unknown in dogs, there is strong evidence of
Dr. N. Madhavan Unny
worsening renal function due to progression of
4(b). Designation cardiovascular diseases and their management.
Assistant Professor,
Department of Veterinary Clinical
Medicine, Ethics and Jurisprudence,
College of Veterinary and Animal Sciences,
Mannuthy, Thrissur- 680 651
Mechanisms involved in CvRDH are CvRDH for better survival outcomes.
decreased kidney perfusion secondary to
decreased cardiac output, activation of 7. Important publications on which the
study is based
neurohormonal systems and generation of
reactive oxygen species. Cardiovascular renal MacDonald et al. (1987) reported that
disorder subtype H is further divided into angiotensin converting enzyme inhibitors
animals with stable and unstable diseases. (ACEI) were nephrotoxic at very high dosages
Acute decompensation of cardiovascular and were associated with volume contraction
system leads to acute worsening of renal and worsening of kidney function.
function (unstable). Chronic cardiovascular
dysfunction and its management may lead to Nicolle et al. (2007) found that fifty
chronic kidney dysfunction (stable). Early percent of one hundred and twenty four dogs
detection of renal dysfunction due to with chronic valvular heart disease were
According to Orvalho and Cowgill estimate serum creatinine and blood urea
leading to acute worsening of renal function haemoparasites will be ruled out by peripheral
(unstable) and chronic cardiorenal syndrome blood smear, buffy coat examination and PCR.
with chronic cardiovascular dysfunction and its Leptopsira will be ruled out using MAT.
Eatroff, A.E., Langston, C.E., Chalhoub, S., Van Israel, N. 2015. Cardiovascular-renal axis
Poeppel, K. and Mitelberg, E. 2012. Long term disorders in the domestic dog and cat: a
outcome of cats and dogs with acute kidney veterinary consensus statement. J. Small Anim.
135 cases (1997-2010). J. Am. Vet. Med. Assoc. Santos, F., Bandt, C. and Bolfer, L.
241:1471-1478. 2015.Extracorporeal blood ultrafiltration in
decompensated congestive heart failure and
International renal interest society,
cardiorenal syndrome. Anclivepa. 2:6-17.
2016.Available:http://www.iriskidney.com/guid
elines/grading.html.
APPENDIX-II
Semester -1 Semester – 5
1. Collection of literature 1. Recruitment of patients
2. Review of literature
2. Categorising into stable and unstable
3. Preparation of project proposal groups
3. Sample collection and analysis
Semester-2
4. Monitoring cases
1. Collection of literature
Semester – 6
2. Review of literature
1. Compilation of data
Semester -3 2. Interpretation of results
1. Recruitment of patients 3. Thesis writing
2. Categorising into stable and unstable 4. Submission of thesis
groups
3. Sample collection and analysis
4. Monitoring cases
Semester -4
1. Recruitment of patients
2. Categorising into stable and unstable
groups
3. Sample collection and analysis
4. Monitoring cases
CERTIFICATE
Certified that the research project has been formulated observing the stipulations laid down under the
Prevention of Cruelty to Animal (Amendment) Act, 1998.