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MSDS VINCRISTINE - Lampiran Drs Masrial M PDF
MSDS VINCRISTINE - Lampiran Drs Masrial M PDF
Toxicological Data on Ingredients: Vincristine sulfate: ORAL (LD50): Acute: 5 mg/kg [Rat].
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Section 4: First Aid Measures
Eye Contact:
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,
keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
Skin Contact:
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin
with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.
Wash contaminated clothing before reusing.
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention.
Ingestion:
Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible
indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen
tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek immediate medical attention.
Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).
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Large Spill: Use a shovel to put the material into a convenient waste disposal container.
Storage:
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly
closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate
locked safety storage cabinet or room.
Personal Protection:
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
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Volatility: Not available.
Polymerization: No.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
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Toxicity of the Products of Biodegradation: The products of degradation are less toxic.
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada):
CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
CLASS D-2B: Material causing other toxic effects (TOXIC).
DSCL (EEC):
R28- Very toxic if swallowed.
R38- Irritating to skin.
R41- Risk of serious damage to eyes.
HMIS (U.S.A.):
Health Hazard: 4
Fire Hazard: 1
Reactivity: 0
Personal Protection: E
Health: 4
Flammability: 1
Reactivity: 0
Specific hazard:
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Protective Equipment:
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
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