You are on page 1of 5

During the first 4 to 5 days of the first week, the zygote undergoes rapid mitotic

division (cleavage) in the oviduct to form a blastula, consisting of increasingly


smaller blastomeres. This becomes the morula (32-cell stage).
A blastocyst forms as fluid develops in the morula. The blastocyst consists of an
inner cell mass known as the embryoblast, and the outer cell mass known as the
trophoblast, which becomes the placenta.
At the end of the first week, the trophoblast differentiates into the cytotrophoblast
and syncytiotrophoblast and then implantation begins (see below).

Implantation
The zona pellucida must degenerate for implantation to occur.
The blastocyst usually implants within the posterior wall of the uterus.
The embryonic pole of blastocyst implants first.
The blastocyst implants within the functional layer of the endometrium during
the progestational phase of the menstrual cycle.

l The embryoblast differentiates into the epiblast and hypoblast, forming


a bilaminar embryonic disk.
l The epiblast forms the amniotic cavity and hypoblast cells migrate to form

the primary yolk sac.


l The prechordal plate, formed from fusion of epiblast and hypoblast

cells, is the site of the future mouth.

You might also like