ILIESCU OCTAVIAN ANDREI CRISTIAN (OCT)

Male
DOB 17.05.2008, born at term
Weight 14 kg
Personal pathological history - none so far
Immunization: last one at 1 year of age
No current treatment
Parents: Iliescu Maria Magdalena, Iliescu Vasile Viorel
Parents’ pathology: mother has compound myopic astigmatism

Day 0: 15.01.2010
- informed consent was signed and parents have received a copy
- mild mucopurulent discharge in RE, severe mucopurulent discharge in LE for 3 days
Slit lamp exam:
RE palpebral edema (0), mucopurulent discharge (+), conjunctival hyperemia +
LE palpebral edema (0) mucopurulent discharge (2+), conjunctival hyperemia 2+
Fluorescein test negative

Day 3: 18.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia +
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 23.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 0
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative

Feedback from mother: satisfactory

Overall treatment satisfaction (mother) satisfied, the baby didn’t complain about the
drops, no pain or burning sensation, easy to apply

Brought back treatment

VOINEA MARIA ELISABETA (MAR)
Female
DOB: 17.07.2003
Weight at birth: approximately 3,800 kg, born at 37 weeks
Personal pathological history: none
No current treatment
Did all immunizations so far
Parents: Voinea Ciprian Crinel, Voinea Alina Alexandrina
Parent’s history: no ocular pathology so far
Weight: 21 kg

18.01.2010
- informed consent was signed and parents have received a copy

Day 0: 19.01.2010
RE: mucopurulent discharge ++, conjunctival hyperemia ++, foreign body sensation +
LE: mucopurulent discharge +, conjunctival hyperemia ++, foreign body sensation +
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Ocular motility + for directions
Informed consent signed by the parents
Recoltation RE, LE – send to the lab

Day 3: 22.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia +
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 25.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 0
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative

Brought back the treatment vials/SDU

BRATU ERICA MARIA (ERI)

Female
DOB: 16.01.2010
Weight at birth 4,100 kg, born at 41 weeks
Personal pathological history: none
No current treatment
Parents: Bratu Cezar Leonard, Bratu Valerica
Parent’s history: no ocular pathology so far
Weight: 3.9 kg

Day 0: 19.01.2010
- informed consent was signed and parents have received a copy
RE: mucopurulent discharge +++, conjunctival hyperemia ++, tearing +, folliculo-
papillary reaction ++, palpebral erythema +
LE: mucopurulent discharge +, conjunctival hyperemia +, tearing 0, folliculo-papillary
reaction +, palpebral erythema 0

Palpebral edema 0, palpebral eritema 0 for BE

Fluorescein test negative
Ocular motility + for directions

Recoltation RE, LE – send to the lab

Day 3: 22.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia +
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 28.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 0
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative

Overall treatment satisfaction (mother) satisfied, the baby didn’t seem to complain about
the drops, no pain or burning sensation, easy to apply

Brought back treatment

GRIGORE BIANCA ALEXANDRA (BIA)

Female
DOB: 18.01.2010
Weight at birth 3,500 kg, born at 40 weeks
Personal pathological history: none
No current treatment
Parents: Grigore Gigi Robert, Grigore Sanda Simona
Parent’s history: no ocular pathology so far
Weight: 3.3 kg

Day 0: 20.01.2010
- informed consent was signed and parents have received a copy
RE: mucopurulent discharge ++, conjunctival hyperemia ++, folliculo-papillary reaction
+
LE: mucopurulent discharge 0, conjunctival hyperemia +, folliculo-papillary reaction 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Ocular motility + for directions
Informed consent signed by the parents
Recoltation RE, LE – send to the lab

Day 3: 23.01.2010
RE: mucopurulent discharge ++, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 27.01.2010
RE: mucopurulent discharge +, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative

Will return for the optional 15 days visit on 04.02.2010

IORDACHE ALEXIA MARIA (ALE)
Female
DOB: 18.01.2010
Weight at birth 3,400 kg, born at 40 weeks
Personal pathological history: none
No current treatment
Parents: Iordache Adrian, Iordache Florentina
Parent’s history: no ocular pathology so far
Weight: 3.2 kg

Day 0: 20.01.2010
- informed consent was signed and parents have received a copy
RE: mucopurulent discharge +, conjunctival hyperemia +
LE: mucopurulent discharge +/-, conjunctival hyperemia +
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Ocular motility + for directions
Recoltation RE. LE – send to the lab

Day 3: 23.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 28.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 0
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative

Forgot to bring back the treatment SDU/vials

DELIU STEFAN BOGDAN (STE)

Male
DOB: 28.07.1993
Personal pathological history: none
No current treatment
Parents: Deliu Marius, Deliu Alina
Parent’s history: no ocular pathology so far
Weight: 63 kg

Day 0: 25.01.2010
- informed consent was signed and parents have received a copy
RE: mucopurulent discharge +, conjunctival hyperemia +, itching +, tearing +
LE: mucopurulent discharge +, conjunctival hyperemia +, itching +, tearing +
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Ocular motility + for directions
Informed consent signed by the parents
Recoltation RE. LE – send to the lab

Day 3: 28.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia +
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 01.02.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 1
LE: mucopurulent discharge 0, conjunctival hyperemia 0
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Brought back treatment

Overall efficiency: very satisfactory

Overall acceptability: satisfactory
KARINA IOANA RADU

female
DOB: 24.09.2009
Weight at birth 3,200 kg, born at 38 weeks
Personal pathological history: none
Immunization: 1st month and 3rd months
No current treatment
Parent’s history: no ocular pathology so far
Weight: 7 kg

Day 0: 28.01.2010 with severe mucopurulent discharge, palpebral oedema for 2 days
- informed consent was signed and parents have received a copy
RE palpebral oedema (0), mucopurulent discharge (1+), conjunctival hyperemia 2+
LE palpebral oedema (2+), mucopurulent discharge (3+), conjunctival hyperemia 3+,
Fluorescein test negative

Day 3: 31.01.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 1, palpebral oedema (0)
LE: mucopurulent discharge 1, conjunctival hyperemia 2, palpebral oedema (1)
Palpebral edema 0, palpebral eritema 0 for BE

Day 7: 03.02.2010
RE: mucopurulent discharge 0, conjunctival hyperemia 0, palpebral oedema (0)
LE: mucopurulent discharge 0, conjunctival hyperemia 1, palpebral oedema (0)
Palpebral edema 0, palpebral eritema 0 for BE
Fluorescein test negative
Brought back treatment

Overall efficiency: very satisfactory

Overall acceptability: satisfactory
CRAP EMA ANISIA

female
DOB: 26.11.2009
Weight at birth 3,100 kg, born at 39 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 6 kg

Day 0: 05.02.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (1+),
conjunctival hyperemia 1+, follicular reaction 1
LE - tearing 2, photophobia 2
- palpebral oedema (2+), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 3+, follicular reaction 3
Fluorescein test negative

Day 3: 08.02.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 1+, follicular reaction 1
LE - tearing 2, photophobia 1
- palpebral oedema (1+), palpebral erithema 1, mucopurulent discharge (2+),
conjunctival hyperemia 2+, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: not very satisfactory

Day 7: 12.02.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (1+),
conjunctival hyperemia 1+, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: not very satisfactory
DRAGUT MIHAI

male
DOB: 19.12.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 12.02.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 15.02.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory

Day 7: 18.02.2010
RE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (1),
conjunctival hyperemia 1, follicular reaction 0
Overall efficiency: satisfactory
Overall acceptability: satisfactory

Day 15: 26.02.2010

BE - mucopurulent discharge (0), conjunctival hyperemia 0, follicular reaction 0
DUMITRESCU EDUARD ALEXANDRU

male
DOB: 15.08.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 15.02.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 18.02.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory

Day 7: 23.02.2010
RE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (1),
conjunctival hyperemia 1, follicular reaction 0
Overall efficiency: satisfactory
Overall acceptability: satisfactory
RADU RAZVAN

male
DOB: 20.10.1995
Personal pathological history: none
Immunization: all
No current treatment
Parent’s history: no ocular pathology so far
Weight: 45 kg

Day 0: 19.02.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 22.02.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory

Day 7: 26.02.2010
RE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (1),
conjunctival hyperemia 1, follicular reaction 0
Overall efficiency: satisfactory
Overall acceptability: satisfactory
CIUSCOI ROXANA
Female
DOB: 01.05.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 24.02.2010 with both eyes mucopurulent discharge

- informed consent was signed and parents have received a copy
RE - tearing 1, photophobia 1
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2+),
conjunctival hyperemia 2, follicular reaction 2
LE - tearing 1, photophobia 1
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 27.02.2010
RE - tearing 1, photophobia 1
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (1+),
conjunctival hyperemia 1, follicular reaction 1
LE - tearing 0, photophobia 1
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (1+),
conjunctival hyperemia 2, follicular reaction 1
Overall efficiency: satisfactory
Overall acceptability: satisfactory

Day 7: 03.03.2010
RE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 1, follicular reaction 0
LE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
Overall efficiency: very satisfactory
Overall acceptability: satisfactory
MIH

male
DOB: 19.12.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 24.02.2010 with right eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 3, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 2
LE - tearing 1, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (2+),
conjunctival hyperemia 2, follicular reaction 0
Fluorescein test negative

Day 3: 27.02.2010
RE - tearing 1, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 1, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
Overall efficiency: very satisfactory
Overall acceptability: very satisfactory

Day 7: 03.03.2010
RE - palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (1),
conjunctival hyperemia 0, follicular reaction 0
Overall efficiency: very satisfactory
Overall acceptability: very satisfactory
MANESCU ANDREI TEODOR

male
DOB: 11.02.2010
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 4.5 kg

Day 0: 03.03.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 06.03.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory
GHITA ERIKA MARIA

female
DOB: 18.01.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 04.03.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 07.03.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory
TAN

male
DOB: 19.12.2009
Weight at birth 3,600 kg, born at 40 weeks
Personal pathological history: none
Immunization: 1st month
No current treatment
Parent’s history: no ocular pathology so far
Weight: 5 kg

Day 0: 05.03.2010 with left eye severe mucopurulent discharge, palpebral oedema for 2
days
- informed consent was signed and parents have received a copy
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 2, mucopurulent discharge (3+),
conjunctival hyperemia 2, follicular reaction 1
Fluorescein test negative

Day 3: 08.03.2010
RE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 0, mucopurulent discharge (0),
conjunctival hyperemia 0, follicular reaction 0
LE - tearing 0, photophobia 0
- palpebral oedema (0), palpebral erithema 1, mucopurulent discharge (2),
conjunctival hyperemia 1, follicular reaction 1
Overall efficiency: not very satisfactory
Overall acceptability: satisfactory