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Questions

1. Draw the mechanism of carbonic anhydrase.


2. Write the mechanism of hydride transfer in liver alcohol dehydrogenase.
3. What are the importance of globin?
4. Define homeostasis and detoxification. How does metal concentration affect cell growth?
5. Show the mechanism of vanadium chloroperoxidase catalysed oxidation of chloride.
6. Draw the mechanism of dinuclear nickel hydrolase.
7. Describe the function of arginase.
8. Write down the structural and functional aspects of urease
9. Name the enzyme which neutralizes the excess acid formed in body. Draw the active site
and explain the mechanism.
10. Draw the structure of active site of arginase and write the equation of its hydrolysis
11. Zinc finger domain displays highest affinity for zinc and not for cobalt. Why?
12. Explain the structure of carboxypeptidase A with diagram
13. Explain with mechanism how alcohol is processed in the body.
14. Name the enzyme responsible for the conversion CO2 to HCO3- and explain the mechanism.
15. Draw the structure of liver alcohol dehydrogenase and explain its catalytic action
16. What is the role of Zn(II) present in liver alcohol dehydrogenase enzyme
17. Write the different types of hydrolytic enzymes and mention the metals present in their
active sites.
18. Write the mechanism of hydrolysis of CO2 by carbonic anhydrase.
19. Other than urea what kind of substrates can be hydrolyzed by Urease?
20. Explain the hydrolysis mechanism of urea by Urease enzyme?
21. What is the significance of zinc in zinc finger domain?
22. What are the factors that influence Ca(II) coordination in Calmodulin?

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