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1. Describe in detail the preparation and utilization of blood components.

2. Describe in detail the donor selection criteria
3. Discuss Hospital transfusion committee.
4. Discuss various measures that can be taken to minimize the use of allogeneic blood
transfusion for elective cardiac surgery.
5. Discuss the role of leukodepletion in blood banking and transfusion medicine practice.
6. Massive transfusion protocol
7. Discuss the reason for incorrect blood transfusion? What measures can be taken to minimize
such events?
8. Describe the new concepts of providing ideally matched Blood for multiply transfused
Thalassemics to prevent Alloimmunisation
9. Discuss about Accreditation of Blood Banks. List in brief logarithmic approach. What are the
Quality Control requirements for accreditation in respect of Blood and Blood components.
10. Design the setting of a Blood Bank for a 500 bedded multispeciality hospital.
11. What are the measures which should be undertaken to ensure a successful & sustained
Voluntary Blood Donor Programme in India. Techniques and strategies to enhance voluntary
blood donation.
12. What are the factors that contribute to pre-transfusion testing? What is electronic cross-
matching and how is it different from conventional crossmatch?
13. Describe various bacteria that can contaminate blood and its components. Discuss the
strategies for prevention of bacterial contamination in blood supply. Add a note on the rapid
platelet bacterial contamination detection technologies
14. The various aspects required to set up a good quality management system in a transfusion
service.
15. Discuss the appropriate investigations and suggested management in a 56 year old male, who
has undergone urgent coronary bypass graft surgery following a failed coronary arterial stent
procedure and has uncontrollable haemorrhage post bypass? He has received streptokinase and
the antiplatelet agents Abciximab (IIb IIIa inhibitor) and clopidogrel over the preceding 6 hours.
16. A 22 year old medical student has been donating blood once a year for the past 3 years. No
problems were encountered for the first two donations. However, on the third donation, the
donated unit was found to be anti-HIV reactive. a) As the person in charge of the Blood
Transfusion Center, how would you manage the situation? b) What actions can be taken to
prevent the re- occurrence of this situation

1. Passenger lymphocyte syndrome

2. Discuss the process to improve the efficiency and Quality assurance of component laboratories.
3. Critically analysed factors affecting quality of cryoprecipitate cryo-preservation of peripheral
blood stem cells.Cryoprecipitate preparation and its applicability.
4. Platelet concentrate preparation and applicability
5. Blood transfusion practices in Neonates , Discuss Transfusion support in a Neonate undergoing
corrective surgery for a congenital heart disease. . Exchange transfusion. Management of
neonatal alloimmune thrombocytopenic purpura.
6. Intrauterine transfusions. Diagnosis and management of a baby with Rh related Haemolytic
disease of the fetus and newborn Evidence based transfusion guidelines for platelets in neonatal
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and older children Most suitable blood component to be used in Preterm neonate, delivered at
32 week of gestation requiring top-up red cell transfusion.
7. Platelet refractoriness
8. Diagnosis of platelet function defects.
9. Computerization in Blood Banks
10. Hemovigilance
11. QC of irradiated components
12. Statergies of blood donor motivation
13. National plasma policy
14. Discuss guidelines for Stem Cell research in India.
15. Ethical issues in transfusion medicine
16. Audit in transfusion practice and its utility
17. Informed consent in Transfusion Medicine
18. National blood policy
19. Blood Donor Counselling.
20. Blood donor notification.
21. Discuss strategies for Blood Donor motivation.
22. “Directed Donation should be discouraged”. Comment on this statement with reasons.
23. Describe stealth RBC’s
24. Discuss the various Viral Inactivation methods used for Blood Products Role of Riboflavin and
Ultraviolet pathogen inactivation in platelets,pathogen reduction technique
25. GMP in blood component laboratory.
26. Transfusion support in ABO mismatched bone marrow transplantation
27. Discuss indications and quality control issues of irradiated blood products.
28. Appropriate uses of intravenous immunoglobulin.
29. Plasma concentration, biological half life and hemostasis levels of various coagulation
factors
30. Plasma products for management of hemophilia A
31. Coagulation derangement in chronic liver disease and its management
32. Thromboelastography
33. Acute normo-volemic hemodilution
34. Indicators of quality in a blood transfusion practice
35. Draw a process flow of your component laboratory and discuss
36. importance of process flow mapping
37. Blood Bank Information Systems
38. Use of washed cells in transfusion practice.
39. A patient has a road traffic accident and is transfused 13 units of blood within 7 hours. Discuss
the transfusion related problems you anticipate, their laboratory evaluation and management.
40. Merits and demerits of directed blood donations
41. Cold chain maintenance and its importance
42. Methods of HLA typing
43. Red cell salvage
44. Management of inadvertent D positive transfusion
45. Duffy group and its interaction with HIV and Malaria
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46. Leapfrog technique in autologous deposits.,autologous donation
47. “Uncrossmatched” red cell units.
48. Most suitable blood component to be used in 32-year old man with relapsed acute myeloid
leukemia on FLAG-IDA (fludarabine, cytosine arabinoside, G-CSF, idarubicin) chemotherapy
regime requiring platelet and red cell support.
49. Most suitable blood component to be used in 25-year old woman with thrombotic
thrombocytopenic purpura (TTP) requiring intensive therapeutic plasma exchange.
50. Advice a 35-year-old Bengali labourer who comes to donate blood? He could not fill in the
donation form and you are unable to counsel him because of language barrier.
51. Advice a 32-year-old regular blood donor has donated whole blood five weeks ago and wants to
donate platelets on this occasion.
52. Transfusion-related acute lung injury (TRALI). , Transfusion reactions of immune etiology.
53. Post transfusion purpura
54. Red cell additive solutions.
55. Therapeutic phlebotomy.
56. Liberal vs restrictive strategy in transfusion practice.
57. Use of filters in transfusion medicine.
58. Methods of NAT testing of blood donors
59. Solid phase adherence assay – applications in transfusion medicine.
60. Cohn process of plasma fractionation and the fractions that are source of various therapeutic
proteins
61. Estimation of survival of transfused radio labelled red cells
62. Extracorporeal Membrane Oxygenation (ECMO).
63. Photopheresis
64. Rare blood group registry.